赵丽娜 - 中国科学院纳米生物效应与安全性重点实验室 -

个人简介

2000年获得北京理工大学应用物理学士学位，2005年获得北京理工大学凝聚态物理博士学位。2005年进入北京大学人工微结构和介观物理国家重点实验室从事博士后研究（合作导师：俞大鹏院士），2006年加入新加坡南洋理工大学Atomistix科学计算中心担任算法科学家。2008年作为“海外优秀人才引进”加入中国科学院高能物理研究所纳米生物效应与安全性重点实验室，聘为副研究员。2020年晋升研究员。在Nature BME、PNAS、ACSNano、Small、JPCL等权威期刊发表SCI文章60余篇，近五年被引1700余次，合著著作1部（Wiley-VCH出版社）。主持国家自然科学基金4项、国家重点研发计划子课题1项、国家重大科研仪器项目子课题1项。获得ACS Nano青年科学家奖

研究领域

（1）纳米生物效应分子机制的多尺度模拟计算研究（2）纳米新材料、药物新结构预测的大数据挖掘研究（3）生物医学图像、同步谱学数据分析的深度学习应用研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

[1] Yanyan Cui, Yaling Wang*, Lina Zhao*, “Cysteine-Ag Cluster Hydrogel Confirmed by Experimental and Numerical Studies”, Small, 11, 5118-5125, 2015. [2] Qingming Deng, Lina Zhao*, Xingfa Gao, Meng Zhang, Youhua Luo, Yuliang Zhao*, “Single Layer of Polymeric Co-Phthalocyanine: Promising Low-Cost and High Activity Nanocatalysts for CO Oxidation”, Small, 9, 3506-3513, 2013. [3] Xudong Feng, Xiaoyan Wang, Beijia Han, Changling Zou, Yuhui Hou, Lina Zhao*, Chun Li*, “Design of Glyco-Linkers at Multiple Structural Levels to Modulate Protein Stability”, J. Phys. Chem. Lett., 9, 4638-4645, 2018. [4] Hui Wang, Xu Li, Liang Gao, Jiao Zhai, Ru Liu, Xueyun Gao, Dongqi Wang, Lina Zhao*, “Atomic structure of a peptide coated gold nanocluster identified using theoretical and experimental studies”, Nanoscale, 8, 11454-11460, 2016. [5] Lina Zhao, Jiao Zhai, Xuejie Zhang, Xueyun Gao*, Xiaohong Fang, Jingyuan Li*, “Computational design of peptide-Au cluster probe for sensitive detection of aIIbb3 integrin”, Nanoscale, 8, 4203-4208, 2016. [6] Xiaohui Yin, Lina Zhao(共同第一作者), Seung-gu Kang, Jun Pan, Yan Song, Mingyi Zhang, Gengmei Xing, Fei Wang, Jingyuan Li*, Ruhong Zhou*, Yuliang Zhao*, “Impacts of fullerene derivatives on regulating the structure and assembly of collagen molecules”, Nanoscale, 5, 7341-7348, 2013. [7] Qingming Deng, Lina Zhao*, Youhua Luo, Meng Zhang, Lixia Zhao, Yuliang Zhao*, “Carbon-Tuned Bonding Method Significantly Enhanced the Hydrogen Storage of BN–Li Complexes”, Nanoscale, 3, 4824-4829, 2011. [8] Qingming Deng, Lina Zhao*, Youhua Luo*, Meng Zhang, Long Jing, Yuliang Zhao*, “Ferromagnetism/ Antiferromagnetism Transition between Semihydrogenated and Fully-Aminated Single-Wall Carbon Nanotubes”, Nanoscale, 3, 3743-3746, 2011. [9] Shibo Xia, Juan Li, Mian Zu, Jinxia Li, Jinke Liu, Xue Bai, Yanan Chang, Kui Chen, Weihong Gu, Li Zeng, Lina Zhao*, Gengyan Xing*, Gengmei Xing*, “Small size fullerenol nanoparticles inhibit thrombosis and blood coagulation through inhibiting activities of thrombin and FXa”, Nanomedicine: NBM, 14, 929-939, 2018. [10] Junjiang Jin, Ying Dong, Ying Wang, Lin Xia, Weihong Gu, Xue Bai, Yanan Chang, Mingyi Zhang, Kui Chen, Juan Li*, Lina Zhao*, Gengmei Xing*, “Fullerenol Nanoparticles with Structural Activity Induce Variable Intracellular Actin Filament Morphologies”, J. Biomed. Nanotechnol., 12, 1234-1244, 2016. [11] Meiqing Liu, Liang Gao, Lina Zhao*, Jian He, Qing Yuan, Peng Zhang, Yawei Zhao, Xueyun Gao*, “Peptide-Au Clusters Induced Tumor Cells Apoptosis via Targeting Glutathione Peroxidase-1: The Molecular Dynamics Assisted Experimental Studies”, Sci. Rep., 7, 131-140, 2017. [12] Kaiyi Wang, Wenyong Su, Fuping Gao, Xueyun Gao, Wenchao Niu, Haodong Yao, Xiaofeng Wang, Lina Zhao*, “Glutathione-Coated Au29(SG)27: Structural Determination Based on Different Combination Styles Confirmed by Experiments”, J. Phys. Chem. C, 123, 13951-13957, 2019. [13] Lina Zhao, Yuliang Zhao*, Ruhong Zhou*, “Novel Design of a Nanoflowmeter Based on Carbon Nanotubes”, J. Phys. Chem. C, 116, 13429-13434, 2012. [14] Qingming Deng, Jun Pan, Xiaohui Yin, Xiaofeng Wang, Lina Zhao*, Seunggu Kang, Camilo A. Jimenez Cruz, Ruhong Zhou, Jingyuan Li*, “Towards High Conductivity, Selectivity and Controllability of Water Desalination with FePc Nanopores”, Phys. Chem. Chem. Phys., 18, 8140-8147, 2016. [15] Liang Yan, Yanan Chang, Wenyan Yin, Xiaodong Liu, Debao Xiao, Gengmei Xing, Lina Zhao*, Zhanjun Gu*, Yuliang Zhao*, “Biocompatible and flexible graphene oxide/ upconversion nanoparticle hybrid film for optical pH sensing”，Phys. Chem. Chem. Phys., 16, 1576-1582, 2014. [16] Qiumei Pu, Yinghao Li, Hong Zhang, Haodong Yao, Bo Zhang, Bingji Hou, Lin Li, Yuliang Zhao, Lina Zhao*, “Screen efficiency comparisons of decision tree and neural network algorithms in machine learning assisted drug design”, Sci. China Chem., 62, 506–514, 2019. [17] Yawei Zhao, Changling Zou, Hongkang Zhao, Lina Zhao*, “Nanoprobes in Biomedical Detection”, Sci. China. Chem., 59, 255-263, 2016. [18] Peng Zhang, Jiao Zhai, Xueyun Gao, Hongkang Zhao, Wenyong Su, Lina Zhao*, “Targeted peptide-Au cluster binds to epidermal growth factor receptor (EGFR) in both active and inactive states: a clue for cancer inhibition through dual pathways”, Sci. Bull., 63, 349-355, 2018. [19] Xu Li, Nan Li, Lina Zhao*, “The Reactive Activities of Natural Amino Acids: Key Principles of Peptide-Templated Au Cluster Synthesis”, Sci. Bull., 61, 1732-1738, 2016. [20] Lili Zhao, Qiao Chen, Yamin Zhang, Lina Zhao*, “Current Induced Heat Generation in Ferromagnet-Quantum Dot-Ferromagnet System”, Materials, 8, 3854-3863, 2015. [21] Yinghao Li, Qiumei Pu, Shuheng Li, Hong Zhang, Xiaofeng Wang, Haodong Yao, Lina Zhao*, “Machine learning methods for research highlight prediction in biomedical effects of nanomaterial application”, Pattern Recogn. Lett. 117, 111-118, 2019. [22] Dan Xie, Yanan Chang, Gengmei Xing, Lina Zhao*, Min Li*, Yuliang Zhao, “Exploring the Interaction of Fullerenol with Key Digestive Proteases Using Raman-Based Frequency-Shift Sensing and Molecular Simulation Analysis”, ACS Appl. Bio Mater., 2, 2946-2954, 2019. [23] Lina Zhao, “Chapter14 Molecular Simulation Methods for Bio-effects of Nanomaterials”, Toxicology of Nanomaterials, 2016. (Wiley-VCH出版)

个人简介

研究领域

近期论文

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