王博 - 海南大学 - 材料与化工学院

研究领域

生物催化, 工业生物技术，药物化学，（生物）有机合成，绿色化学

近期论文

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(1) Wang Bo, Land Henrik, and Berglund Per*, Efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase, Chemical Communications, 2013, 49, 161-163.(2) Wang Bo*, Liu Yanfeng, Zhang Dela, Feng Yuhong and Li Jiacheng, Efficient kinetic resolution of amino acid catalyzed by lipase AS „Amano‟ via cleavage of amide bond, Tetrahedron: Asymmetry, 2012, 23, 1338-1342.(3) Wang Bo ,Jiang Ling, Wang Jue, Wang Dan, Liu Min and Yu Hongwei*, A tandem and fully enzymatic procedure for green resolution of chiral alcohol: acylation and deacylation in non-aqueous media, Tetrahedron: Asymmetry, 2011, 22, 980-985. (4) Wang Bo ,Tang Xiaoling, Ren Gangfeng, Liu Ji, and Yu Hongwei*, Escherichia coli BioH: an esterase with high activity and enantioselectivity for kinetic resolution of secondary alcohols in organic solvents. Tetrahedron Letters，2010, 51, 6360-6364.(5) Wang Bo ,Liu Ji, Tang Xiaoling, Cheng Cheng, Gu Jiali, Dai Liyan*, Yu Hongwei*, Enzymatic synthesis of (S)-glutaric acid monoesters aided by molecular docking，Tetrahedron Letters，2010，51，309-312. (6) Wang Bo ,Tang Xiaoling, Ren Gangfeng, Liu Ji, Yu Hongwei*, A new high-throughput screening method for determining active and enantioselective hydrolases, Biochemical Engineering Journal, 2009, 46, 345-349. (7) Wang Bo*, Yu Chuan Ming, Chen Zhi Wei, Su Wei Ke, An efficient method for the synthesis of dialkyl chlorophosphates from trialkyl phosphites using bis(trichloromethyl) carbonate, Chinese Chemical Letters, 2008, 19, 904-906.(8) Hongyin Yang, Wenjian Hu, Shengjue Deng, Tiantian Wu, Haiman Cen, Yiping Chen,Dela ZhangandBo Wang*Catalyst-free amidation of aldehyde with amine under mild conditions，New Journal of Chemistry，2015, 39，5912-5915.(9) Jiang Ling, Wang Bo, Li Rongrong, Shen Sa, Yu Hongwei, Ye Lidan, Catalytic promiscuity ofEscherichia coliBioH esterase: Application in the synthesis of 3,4-dihydropyran derivatives, Process Biochemistry, 2014, 49, 1135–1138.(10) Jiang Ling, Wang Bo, Li Rongrong, Shen Sa, Yu Hongwei, Ye Lidan, “Amano” lipase DF-catalyzed efficient synthesis of 2,2′-arylmethylene dicyclohexane-1,3-dione derivatives in anhydrous media, Chinese Chemical Letters, 2014, 25，1190-1192. (11) Tang Xiaoling, Liu Ji, Wang Bo，Yu Hongwei*, Cloning, screening and characterization of enantioselective ester hydrolases from Escherichia coli K-12, World Journal of Microbiology and Biotechnology, 2011, 27, 129-136. (12) Liu Ji, Tang Xiaoling, Wang Bo,Yu Hongwei*, Min Hang, Cloning, screening and characterization of ester hydrolases with enantioselectivity in typical bacteria, Process Biochemistry, 2010, 45, 475-480.(13) Wang Jue, Wang Dan, Wang Bo,Liu Ji, Mei Zhuohang and Yu Hongwei*, Enhanced activity of Rhizomucor miehei Lipase by directed evolution with simultaneous evolution of the propeptide. Applied Microbiology and Biotechnology, 2012, 96, 443 -450.(14) Wang Dan, Wang Jue, Wang Boand Yu Hongwei*, A New and Efficient Colorimetric High-throughput Screening Method for Triacylglycerol Lipase Directed Evolution, Journal of Molecular Catalysis B: Enzymatic, 2012, 82, 18-23. (15) Yu Chuan-Ming*, Wang Bo, Chen Zhi-Wei, A Novel Synthesis of Alkylamino Substituted Methylenediphosphonates Using Bis(trichloromethyl) Carbonate and RCONR1R2, Chinese Journal of Chemistry, 2008, 26, 1899-1901.