Wennemers, Helma - Eidgenössische Technische Hochschule Zürich - Department of Chemistry and Applied Biosciences

个人简介

Professional appointments since 10/2011 Professor of Organic Chemistry at the ETH Zürich 2003 - 2011 Associate Professor at the University of Basel 1999 - 2003 Assistant Professor at the University of Basel Education 1996 - 1998 Postdoc with Prof. Hisashi Yamamoto, Nagoya University 1993 - 1996 PhD thesis with Prof. W. Clark Still, Columbia University, NY 1992 - 1993 Diplom thesis with Prof. Gerhard Quinkert, Frankfurt 1988 - 1992 Studies of chemistry at Frankfurt University

研究领域

Asymmetric Catalysis Chemical Biology Synthetic Materials Metal Nanoparticles The Wennemers group uses organic synthesis to tackle challenges in asymmetric catalysis, chemical biology, new synthetic materials and metal nanoparticles.

近期论文

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J. Egli, C. Siebler, M. Köhler, R. Zenobi, H. Wennemers "Hydrophobic Moieties Bestow Fast-Folding and Hyperstability on Collagen Triple Helices", J. Am. Chem. Soc., 2019, in press. Abstract R. J. B. Schäfer, M. R. Aronoff, H. Wennemers "Recent Advances in Bioorthogonal Reactions" Chimia 2019, in press. T. Schnitzer, H. Wennemers "Effect of β3-Amino Acids on the Performance of the Peptidic Catalyst H-dPro-Pro-Glu-NH2", Helv. Chim. Acta, 2019, asap. Abstract C. Foletti, N. Trapp, S. Loosli, B. Lewandowski, H. Wennemers “4-Naphthylmethyl Proline Forms a Channel Structure”Helv. Chim. Acta 2019, asap. Abstract S. Loosli,* C. Foletti,* M. Papmeyer, H. Wennemers “Synthesis of 4-(Arylmethyl)proline Derivatives” Synlett 2019, 30, 508–510. Abstract Highlight in Synform E. Cosimi, N. Trapp, M.-O. Ebert, H. Wennemers "Combined Experimental and Theoretical Study of Long-Range H-F Interactions in α-Fluoro Amides”Chem. Commun. 2019, 55, 2253–2256. Abstract M. R. Aronoff,* J. Egli,* M. Menichelli, H. Wennemers "γ-Azaproline Confers pH-Responsiveness and Functionalizability on Collagen Triple Helices”Angew. Chem. Int. Ed. 2019, 58, 3143–3146. Abstract A. Ritler, M. S. Shoshan, X. Deupi, P. Wilhelm, R. Schibli, H. Wennemers, M. Béhé "Elucidating the Structure−Activity Relationship of the Pentaglutamic Acid Sequence of Minigastrin with Cholecystokinin Receptor Subtype 2" Bioconjugate Chem. 2019, 30, 657−666. Abstract M. S. Shoshan, T. Vonderach, B. Hattendorf, H. Wennemers "Peptide‐coated Platinum Nanoparticles with Selective Toxicity against Liver Cancer Cells”Angew. Chem. Int. Ed. 2019, 58, 4901-4905. Abstract Highlight at ETH Highlight at AerzteZeitung C. Rigling, J. K. Kisunzu, J. Duschmalé, D. Häussinger, M. Wiesner, M. O. Ebert, H. Wennemers "Conformational Properties of a Peptidic Catalyst: Insights from NMR Spectroscopic Studies"J. Am. Chem. Soc., 2018, 140, 10829-10838. Abstract T. Schnitzer, H. Wennemers "Effect of γ-Substituted Proline Derivatives on the Performance of the Peptidic Catalyst H-DPro-Pro-Glu-NH2"Synthesis 2018, 22, 4377-4382. Abstract U. Lewandowska,* S. Corra,* W. Zajaczkowski,* N. A. K. Ochs,* M. S. Shoshan, J. Tanabe, S. Stappert, C. Li, E. Yashima, W. Pisula, K. Müllen, and H. Wennemers "Positional Isomers of Chromophore-Peptide Conjugates Self-Assemble Into Different Morphologies"Chem. Eur. J. 2018, 24, 12623-12629. Abstract C. Foletti, R. A. Kramer, H. Mauser, U. Jenal, K. H. Bleicher, H. Wennemers "Functionalized Proline-Rich Peptides Bind the Bacterial Second Messenger c-di-GMP”Angew. Chem, Int. Ed. 2018, 57, 7729-7733. Abstract Highlight in ChemViews T. Schnitzer, H. Wennemers "Influence of the trans/cis Conformer Ratio on the Stereoselectivity of Peptidic Catalysts”J. Am. Chem. Soc., 2017, 139, 15356-15362. Abstract J. Egli, R. S. Erdmann, P. J. Schmidt, H. Wennemers, „Effect of N- and C-terminal functional groups on the stability of collagen triple helices”Chem. Commun. 2017, 53, 11036-11039. Abstract O. D. Engl, J. Saadi, E. Cosimi, H. Wennemers "Synthesis of Monothiomalonates (MTMs) – Versatile Thioester Enolate Equivalents for C–C Bond Formations”Helv. Chim. Acta, 2017, 100, e1700196. Abstract N. B. Hentzen, L. E. J. Smeenk, J. Witek, S. Riniker, H. Wennemers "Cross-Linked Collagen Triple Helices by Oxime Ligation”J. Am. Chem. Soc., 2017, 139, 12815–12820. Abstract S. Dobitz, M. R. Aronoff, H. Wennemers, "Oligoprolines as Molecular Entities for Controlling Distance in Biological and Material Sciences”Acc. Chem. Res., 2017, 50, 2420–2428. Abstract S. Corra, M. S. Shoshan, H. Wennemers, "Peptide mediated formation of noble metal nanoparticles – Controlling size and spatial arrangement"Curr. Opin., Chem. Biol., 2017, 40, 138–144. U. Lewandowska, W. Zajaczkowski,* S. Corra,* J. Tanabe, R. Borrmann, E. M. Benetti, S. Stappert, K. Watanabe, N. A. K. Ochs, R. Schaeublin, C. Li, E. Yashima, W. Pisula, K. Müllen, H. Wennemers "A Triaxial Supramolecular Weave"Nat. Chem., 2017, 9, 1068–1072. Abstract Cover page Highlight in C&EN Highlight at ETH Highlight in Nature Chem.