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1. Tsang WP, Shu Y, Kwok PL, Zhang F, Lee KKH, Tang MK, Li G, Chan KM,
Chan WY, Wan C. CD146+ human umbilical cord perivascular cells maintain
stemness under hypoxia and as a cell source for skeletal regeneration. PLoS
One. 2013；8(10):e76153.
2. Liu W, Li X, Zhao Y, Meng XM, Wan C, Yang B, Lan HY, Lin HY, Xia Y.
Dragon (RGMb) inhibits E-Cadherin expression and induces apoptosis in
renal tubular epithelial cells. J Biol Chem. 2013; 288(44):31528-39.
3. Meng F, Rui Y, Xu L, Wan C, Jiang X, Li G. Aqp1 enhances migration of
bone marrow mesenchymal stem cells through regulation of FAK and
β-catenin. Stem Cells Dev. 2013 Sep 27. [Epub ahead of print]
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4. Yao D, Xie XH, Wang XL, Wan C, Lee YW, Chen SH, Pei DQ, Wang YX, Li
G, Qin L. Icaritin, an exogenous phytomolecule, enhances osteogenesis but not
angiogenesis-an in vitro efficacy study. PLoS One. 2012; 7(8):e41264.
5. Zhu XM, Wang YX, Leung KC, Lee SF, Zhao F, Wang DW, Lai JM, Wan C,
Cheng CH, Ahuja AT. Enhanced cellular uptake of aminosilane-coated
superparamagnetic iron oxide nanoparticles in mammalian cell lines. Int J
Nanomedicine. 2012,7:953-64.
6. Zhang W, Shen X, Wan C, Zhao Q, Zhang L, Zhou Q, Deng L. Effects of
insulin and insulin-like growth factor 1 on osteoblast proliferation and
differentiation: differential signalling via Akt and ERK. Cell Biochem Funct.
2012, 30(4):297-302.
7. Lu L, Cheng Q, Chen J, Yang G, Wan C, Zhang Y, Li Q. The influence of
dietary sodium on bone development in growing rats. Arch Anim Nutr. 2011,
65(6):486-496.
8. Bian Q, Liang QQ, Wan C, Hou W, Li CG, Zhao YJ, Lu S, Shi Q, Wang YJ.
Prolonged upright posture induces calcified hypertrophy in the cartilage
end-plate in rat lumbar spine. Spine (Phila Pa 1976). 2011, 36(24):2011-2020.
9. Bian Q, Liang QQ, Hou W, Wan C, Li CG, Zhao YJ, Lu S, Shi Q, Wang YJ.
Prolonged and repeated upright posture promotes bone formation in rat lumbar
vertebrae. Spine (Phila Pa 1976). 2011, 36(6):E380-7.
10. Fulzele K, Riddle RC, Digirolamo DJ, Cao X, Wan C, Chen D, Faugere MC,
Aja S, Hussain MA, Brüning JC, Clemens TL. Insulin receptor signaling in
osteoblasts regulates postnatal bone acquisition and body composition. Cell.
2010, 142(2):309-319.
11. Wan C, Shao J, Gilbert SR, Riddle RC, Long F, Johnson RS, Schipani E,
Clemens TL. Role of HIF-1α in skeletal development. Ann N Y Acad Sci.
2010, 1192(1):322-326.
12. Kumar S, Wan C, Ramaswamy G, Clemens TL, Ponnazhagan S.
Mesenchymal stem cells expressing osteogenic and angiogenic factors
synergistically enhance bone formation in a mouse model of segmental bone
defect. Mol Ther. 2010, 18(5):1026-1034.
13. Weinstein RS, Wan C, Liu QL, Wang Y, Almeida M, O’Brien CA, Thostenson
J, Roberson PK, Boskey AL, Clemens TL,
Manolagas SC.
Endogenous
glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and
strength in aged mice. Aging Cell. 2010, 9(2):147-161.
14. Shomento SH, Wan C, Cao X, Faugere MC, Bouxsein ML, Clemens TL,
Riddle RC. Hypoxia-inducible factors 1alpha and 2alpha exert both distinct
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and overlapping functions in long bone development. J Cell Biochem. 2010,
109(1):196-204.
15. Shen X, Wan C, Ramaswamy G, Mavalli M, Wang Y, Duvall CL, Deng LF,
Guldberg RE, Eberhart A, Clemens TL, Gilbert SR. Prolyl hydroxylase
inhibitors increase neoangiogenesis and callus formation following femur
fracture in mice. J Orthop Res. 2009, 27(10):1298-1305.
16. Tang Y, Wu X, Lei W, Pang L, Wan C, Shi Z, Zhao L, Nagy TR, Peng X, Hu
J, Feng X, Van Hul W, Wan M, Cao X. TGF-beta1-induced migration of bone
mesenchymal stem cells couples bone resorption with formation. Nat Med.
2009, 15(7):757-765.
17. Zhang F, Shi W, Qiu T, Wu X, Wan C, Wang Y, Wan M, Clemens TL, Cao X.
Sustained BMP signaling in osteoblasts stimulates bone formation by
promoting angiogenesis and osteoblast differentiation. J Bone Miner Res.
2009, 24(7):1224-1233.
18. Wan C, Gilbert SR, Wang Y, Cao XM, Shen X, Ramaswamy G, Jacobsen KA,
Alaql ZS, Gerstenfeld LC, Einhorn TA, Eberhardt AW, Deng L, Guldberg RE,
Clemens TL. Role of hypoxia inducible factor-1alpha pathway in bone
regeneration. J Musculoskelet Neuronal Interact. 2008, 8(4):323-324.
19. Zylstra CR, Wan C, Vankoevering KK, Sanders AK, Lindvall C, Clemens TL,
Williams BO. Gene targeting approaches in mice: Assessing the roles of LRP5
and LRP6 in osteoblasts. J Musculoskelet Neuronal Interact. 2008,
8(4):291-293.
20. Wang Y, Wan C, Szoke G, Ryaby JT, Li G. Local injection of thrombin-related
peptide (TP508) in PPF/PLGA microparticles-enhanced bone formation
during distraction osteogenesis. J Orthop Res. 2008, 26(4):539-46.
21. Mak KK, Bi Y, Wan C, Chuang P-T, Clemens T, Young M, Yang Y. Hedgehog
signaling in mature osteoblasts regulates bone formation and resorption by
controlling PTHrP and RANKL expression. Dev Cell. 2008, 14(5):674-688.
22. Jacobsen KA, Alaql ZS, Wan C, Jennifer L, Fitch BS, Mason ZD, Cole RM,
Gilbert SR, Clemens TL, Morgan EF, Einhorn TA, Gerstenfeld LC. Bone
formation during distraction osteogenesis is dependent on both VEGFR1 and
VEGFR2 signaling. J Bone Miner Res. 2008, 23(5):596-609.
23. Wan C, Gilbert SR, Wang Y, Cao XM, Shen X, Ramaswamy G, Jacobsen KA,
Alaql ZS, Gerstenfeld LC, Einhorn TA, Guldberg RE, Deng L, Clemens TL.
Activation of the hypoxia inducible factor pathway accelerates bone
regeneration. Proc Natl Acad Sci USA. 2008, (105): 686-691.
24. Wang Y, Wan C, Gilbert SR, Clemens TL. Oxygen sensing and osteogenesis.
Ann N Y Acad Sci. 2007, 1117:1-11.
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25. Wang Y, Wan C, Deng L, Liu X, Cao X, Gilbert SR, Bouxsein ML, Faugere
M-C, Guldberg RE, Gerstenfeld LC, Haase VH, Johnson RS, Schipani E,
Clemens TL. The hypoxia inducible factor pathway couples angiogenesis to
osteogenesis during skeletal development. J Clin Invest. 2007, 117 (6):
1616-1626.
26. Liu X, Bruxvoort K, Zylstra CR, Liu J, Cichowski R, Faugere M-C, Bouxsein
ML, Wan C, Williams BO, Clemens TL. Lifelong accumulation of bone in
mice lacking PTEN in osteoblasts. Proc Natl Acad Sci USA. 2007, 104(7):
2259-2264.
27. He Q, Wan C, Li G. Multi-potent mesenchymal stromal cells in blood. Stem
Cells. 2007, 25(1):69-77.
28. Chen X, Xu H, Wan C, McCaigue M, Li G. Bioreactor expansion of human
adult bone marrow-derived mesenchymal stem cells (MSCs). Stem Cells. 2006,
24(9):2052-2059.
29. Wan C, He Q, Li G. Allogenic peripheral blood derived mesenchymal stem
cells (MSCs) enhance bone regeneration in rabbit ulna critical-sized bone
defect model. J Orthop Res. 2006, 24(4):610-618.
30. Wan C, He Q, McCaige M, Marsh D, Li G.. Nonadherent cell population of
human marrow culture is a complementary source of mesenchymal stem cells
(MSCs). J Orthop Res. 2006, 24(1):21-28.
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