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1. Yu S, YaoY, Xiao H, Li J, Liu Q, Yang Y , Adah D, Lu J, Zhao S, Qin L, Chen X. Simultaneously knockout of CXCR4 and CCR5 genes in CD4+ T cells via CRISPR/Cas9 confers resistance to both X4- and R5-tropic HIV-1 infection. Human Gene Therapy. 2017.
2. Qin L, Chen C, Chen L, Xue R, Ou-Yang M, Zhou C, Zhao S, He Z, Xia Y, He J, Liu P, Zhong N, Chen X. Worldwide malaria incidence and cancer mortality are inversely associated. Infect Agent Cancer. 2017, 12:14.
3. Liu Q, Yang Y, Tan X, Tao Z, Adah D, Yu S, Lu J, Zhao S, Qin L, Qin L, Chen X. Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector. Oncotarget. 2017, 8(15):24785-24796.
4.Yang Y, Liu Q, Lu J, Adah D, Yu S, Zhao S, Yao Y, Qin L, Qin L-M, Chen X.Exosomes from Plasmodium-infected hosts inhibit tumor angiogenesis in a murine Lewis lung cancer model. Oncogenesis, 2017, 6 (6):e351.
5.Lu J, Tong Y, Pan J, Yang Y, Liu Q, Tan X, Zhao S, Qin L, Chen X. A redesigned CRISPR/Cas9 system for marker-free genome editing in Plasmodium falciparum. Parasit Vectors. 2016; 11; 9(1):198.
6.Adaha D, Hussain M, Qin L-M, Qin L, Zhang J, Chen X. Implications of MDSCs-targeting in lung cancer chemo-immunotherapeutics. Pharmaceutical Research. 2016.05.00.
7.Qin LM, Yang Y, Liu Q, Xu W, Zhao S, Qin L, Chen X. Down-regulated lncRNA F630028O10Rik contributes to suppress lung cancer in mice through inhibiting miR-223-3p and VEGF signaling pathway (Abstract). Chest. 2016; 150: 261.
8.Li Z, Liu G, Tong Y, Zhang M, Xu Y, Qin L, Wang Z, Chen X, He J. Comprehensive analysis of the T-cell receptor beta chain gene in rhesus monkey by high throughput sequencing. Scientific Reports. 2015, 11;5: 10092.
9. Song H, Hu W, Naowarojna N, Her AS, Wang S, Desai R, Qin L, Chen X, Liu P. Mechanistic studies of a novel C-S lyase in ergothioneine biosyntheses: the involvement of a sulfenic acid intermediate. Scientific Reports. 2015, 7; 5: 11870.
10.Meyers MJ, Anderson EJ, McNitt SA, Krenning TM, Singh M, Xu J, Zeng W, Qin L, Xu W, Zhao S, Qin L, Eickhoff CS, Oliva J, Campbell MA, Arnett SD, Prinsen MJ, Griggs DW, Ruminski PG, Goldberg DE, Ding K, Liu X, Tu Z, Tortorella MD3, Sverdrup FM, Chen X. Evaluation of spiropiperidine hydantoins as a novel class of antimalarial agents. Bioorg Med Chem. 2015, 15; 23 (16): 5144-50.
11.Qin L, Qin L, Xu W, Zhao S, Chen X. Ritonavir-boosted indinavir but not lopinavir inhibits erythrocytic stage Plasmodium knowlesi malaria in rhesus macaques. Bioorg Med Chem Lett. 2015, 1; 25 (7): 1538-40.
12.Zhan XY, Wang N, Liu G, Qin L, Xu W, Zhao S, Qin L, Chen X. Plasmodium infection reduces the volume of the viral reservoir in SIV-infected rhesus macaques receiving antiretroviral therapy. Retrovirology. 2014, 9; 11 (1): 112.
13.Hu W, Song H, Sae Her A, Bak DW, Naowarojna N, Elliott SJ, Qin L, Chen X, Liu P. Bioinformatic and biochemical characterizations of C-S bond formation and cleavage enzymes in the fungus Neurospora crassa ergothioneine biosynthetic pathway. Org Lett. 2014, 17; 16 (20): 5382-5
14.Meyers MJ, Tortorella MD, Xu J, Qin L, He Z, Lang X, Zeng W, Xu W, Qin L, Prinsen MJ, Sverdrup FM, Eickhoff CS, Griggs DW, Oliva J, Ruminski PG, Jacobsen EJ, Campbell MA, Wood DC, Goldberg DE, Liu X, Lu Y, Lu X, Tu Z, Lu X, Ding K, Chen X. Evaluation of aminohydantoins as a novel class of antimalarial agents. ACS Med Chem Lett. 2013, 6; 5 (1): 89-93.
15.Ru R, Yao Y , Yu S, Yin B, Xu W, Zhao S, Qin L and Chen X. Targeted genome engineering in human induced pluripotent stem cells by penetrating TALENs. Cell Regeneration. 2013, 2:5 doi:10.1186/2045-9769-2-5
16.Yao Y, Nashun B, Zhou T, Qin L, Qin L, Zhao S, Xu J, Esteban M, Chen X. Generation of CD34+ Cells from CCR5-disrupted Human Embryonic and Induced Pluripotent Stem Cells. Human Gene Therapy. 2012, 23: 238-242.
17.Li Q, Ruan Z, Zhang H, Peng N, Zhao S, Qin L, Chen X. Characterization of peripheral blood T lymphocyte subsets in Chinese rhesus macaques with repeated or long-term infection with Plasmodium cynomolgi. Parasitol Res. 2012, 110 (2): 961-9.
18.Chen L, He Z, Qin L, Li Q, Shi X, Zhao S,Chen L, Zhong N, Chen X. Antitumor effect of malaria parasite infection in a murine Lewis lung cancer model through induction of innate and adaptive immunity. PLoS ONE. 2011, 6 (9): e24407.
19.Li X, He Z, Chen L, Li Y, Li Q, Zhao S, Tao Z, Hu W, Qin L, Chen X. Synergy of the antiretroviral protease inhibitor indinavir and chloroquine against malaria parasites in vitro and in vivo. Parasitol Res. 2011; 109: 1519-1524.
20.Wang B, Li Q, Qin L, Zhao S, Wang J, Chen X. Transition of tumor-associated macrophages from MHC class IIhi to MHC class IIlow mediates tumor progression in mice. BMC Immunol. 2011; 12: 43.
21.Li Y, Qin L, Peng N, Liu G, Zhao S, He Z, Chen X. The Antimalarial effect of human immunodeficiency virus protease inhibitors in rhesus macaques. Antimicrob Agents Chemother. 2011, 55: 3039-42.
22.Jiang B, Qin L, Du Y, Peng N, Chen L, Chen Z, Chen X. Transgenic Plasmodium that expresses HIV-1 Gag elicits immunity and protects mice against vaccinia virus-gag and malarial parasites. Vaccine. 2010, 28: 7915-7922
23.You J, He Z, Chen L, Deng G, Liu W, Qin L, Qiu F and Chen X. CH05-10, a novel indinavir analog, is a broad spectrum antitumor agent that induces cell cycle arrest, apoptosis, endoplasmic reticulum stress and autophagy. Cancer Science. 2010; 101:2644-51.
24.Xu L, He Z, Xue J, Chen X, Wei X. Beta-Resorcylic acid lactones from a Paecilomyces fungus. J Nat Prod. 2010; 73:885-9.
25.You J, Dai H, Chen Z, Liu G, He Z, Song F, Yang X, Fu H, Zhang L, Chen X. Trichoderone, a novel cytotoxic cyclopentenone and cholesta-7,22-diene-3b, 5a, 6b-triol, with new activities from the marine-derived fungus Trichoderma sp. J Ind Microbiol Biotechnol. 2010; 37:245-52.
26.He Z, Chen L, You J, Li Y, Zhao S, Qin L and Chen X. In vitro interaction between antiretroviral protease inhibitors and artemisinin endoperoxides against Plasmodium falciparum. International Journal of Antimicrobial Agents. 2010; 35:191-193.
27.He Z, Chen L, You J, Qin L, Chen X. Antiretroviral protease inhibitors potentiate chloroquine antimalarial activity in malaria parasites by regulating intracellular glutathione metabolism. Experimental Parasitology, 2009; 123:122-127.
28.Shi X, Qin L, Liu G, Zhao S, Peng N, Chen X. Dynamic balance of pSTAT1 and pSTAT3 in C57BL/6 mice infected with lethal or non-lethal Plasmodium yoelii. Cell Mol Immunol, 2008; 5:341-348.
29.He Z, Qin L, Chen L, Peng N, You J and Chen X. Synergy of human immunodeficiency virus protease inhibitors with chloroquine against Plasmodium falciparum in vitro and Plasmodium chabaudi in vivo. Antimicro Agents Chemother. 2008; 52: 2653-56.
30.Zhang L, Yan K, Zhang Y, Huang R, Bian J, Zheng C, Sun H, Chen Z, Sun N, An R, Min F, Zhao W, Zhuo Y, You J, Song Y, Yu Z, Liu Z, Yang K, Gao H, Dai H, Zhang X, Wang J, Fu C, Pei G, Liu J, Zhang S, Goodfellow M, Jiang Y, Kuai J, Zhou G and Chen X. High-throughput synergy screening identifies beauvericin as a novel combination agent for the treatment of fungal infections. Proc Natl Acad Sci USA. 2007; 104:4606-4611.
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