韩世清 - 南京工业大学 - 生物与制药工程学院

个人简介

教育背景 1982-1986，南京师范大学，理学学士 1986-1989，中国科学院大连化学物理研究所，理学硕士 1996-1999，中国科学院上海有机化学研究所，理学博士 1999-2000，美国Texas A&M University大学，博士后 2000-2002，美国 University of North Carolina at Chapel Hill大学，博士后工作经历 1989-1996，中国科学院大连化学物理研究所，助理研究员； 2002-2002，上海药明康德PharmaTech新药研发公司，高级研究员Senior Scientist II，项目负责人Project Manager, 科研组长Group Header 2002-2003，瑞士罗氏Roche制药(巴塞里亚Basilea药物)中国研发中心，科研处长Division Header 2003-2005，美国礼来Eli Lilly制药公司上海（开拓者化学)研发中心，总监Director 2005起，南京工业大学生物与制药工程学院，研究员(Professor)

研究领域

生物工程专业英语、高等有机化学、科技英语论文写作、生物有机化学、环境工程概论、药物合成反应

近期论文

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Xin Wang, Xiaotong Li, Renhe Hua, Zhao Yang, Ren Gu, Sai Ding, Pengyi Li, Shiqing Han(通讯作者), Elemental Sulfur-Mediated Decarboxylative Redox Cyclization Reaction: Copper-Catalyzed Synthesis of 2-Substituted Benzothiazoles, Synlett, 2018, 29, 219-224. Xin Wang, Dazhuang Miao, Xiaotong Li, Renhe Hua, Zhao Yang, Ren Gu, Shiqing Han(通讯作者), Elemental Sulfur Mediated Cyclization via Redox Strategy: Synthesis of Benzothiazoles from o-Chloronitrobenzenes and Benzyl chlorides, Tetrahedron, 2017, 73, 5194-5199. Zhao Yang, Renhe Hu, Xiaotong Li, Xin Wang, Ren Gu, Shiqing Han(通讯作者), One-pot Copper-Catalyzed Synthesis of 2-Substituted Benzothiazoles from 2-Iodoanilines, Benzyl Chlorides and Elemental Sulfur, Tetrahedron Letters, 2017, 58, 2366～2369. Haifeng Gan, Dazhuang Miao, Qiang Pan, Renhe Hu, Xiaotong Li, and Shiqing Han(通讯作者), S8-Mediated Cyclization of 2-Amino Phenols/Thiophenols with Arylmethyl Chloride: Approach to Benzoxazoles and Benzothiaz, Chemistry – An Asian Journal, 2016, 11, 1770-1774. Xiaotong Li, Qiang Pan, Renhe Hu, Xin Wang, Zhao Yang, and Shiqing Han(通讯作者), S8-Mediated One-Pot Synthesis of Thioamides from Benzyl Chlorides and Amines, Asian Journal of Organic Chemistry, 2016, 5, 1353-1358. Xiaotong Li, Renhe Hu, Yao Tong, Qiang Pan, Dazhuang Miao, Shiqing Han(通讯作者), An Efficient Route for the Synthesis of Benzimidazoles via a Hydrogen-Transfer Strategy between o-nitroanilines and Alcohols, Tetrahedron Letters, 2016, 57, 4645-4649. Renhe Hu, Xiaotong Li, Yao Tong, Dazhuang Miao, Qiang Pan, Zengqiang Jiang, Haifeng Gan, Shiqing Han(通讯作者), Catalyst-Free Synthesis of 2-Arylbenzothiazoles in an Air/DMSO Oxidant System, Synlett, 2016, 27, 1387-1390. Qiang Pan, Chun-Yang He, Shiqing Han(通讯作者), Xingang Zhang, Palladium-Catalyzed Direct Thienylation of Monobromide-Substituted Difluorinated Benzothiadiazoles for Organic Photovoltaics, Synlett, 2015, 26, 2175-2179. Zeng-qiang Jiang, Da-zhuang Miao, Yao Tong, Qiang Pan, Xiao-tong Li, Ren-he Hu, Shiqing Han(通讯作者), One-Pot Base-Mediated Synthesis of Functionalized Aza-Fused Polycyclic Quinoline Derivatives, Synthesis, 2015, 47, 1913-1921. Dazhuang Miao, Xuesong Shi, Guozhen He, Yao Tong, Zengqiang Jiang, Shiqing Han(通讯作者), One-pot synthesis of 2-arylbenzoxazole derivatives via Cu(I) catalyzed C-N/C-O coupling of N-(2-chloro-phenyl)-2-halobenzamides and primary amines, Tetrahedron, 2015, 71, 431-435. Yao Tong, Qiang Pan, Zengqiang Jiang, Dazhuang Miao, Xuesong Shi, Shiqing Han(通讯作者), A simple approach to benzothiazoles from 2-chloronitrobenzene, elemental sulfur, and aliphatic amine under solvent-free and catalyst-free conditions, Tetrahedron Letters, 2014, 55, 5499-5503. Zengqiang Jiang, Jie Zhang, Yao Tong, Xuesong Shi, Dazhuang Miao, Shiqing Han(通讯作者), One-Pot Synthesis of Pyrrolo[1,2-a]quinoxaline Derivatives through Copper-Catalyzed Cascade Reactions, Chin. J. Org. Chem. 2014, 34, 1845-1850. Guozhen He, Yuan Huang, Yao Tong, Jie Zhang, Dan Zhao, Shuangli Zhou, Shiqing Han(通讯作者),Substrate-Promoted Ligand-Free CuI Catalyzed S-Arylation of 2-Mercapto- benzothiazoles with Aryl Iodides in Water, Tetrahedron Letters, 2013, 54, 5318–5321. Ming Jin, Dan Zhao, Guozhen He, Yao Tong, Shiqing Han(通讯作者), Substrate-promoted copper-catalyzed N-arylation of amino alcohols with aryl iodides in water, Chinese Journal of Catalysis, 2013, 34 (9), 1651-1655. Yuan Huang, Wei Chen, Dan Zhao, Chen Chen, Huiqing Yin, Likang Zheng, Ming Jin, Shiqing Han(通讯作者), Copper(I)-Catalyzed Intramolecular Direct C-Arylation of Azoles with Aryl Bromides, Chinese Journal of Chemistry, 2013, 31, 1007-1010. Jie Zhang, Zengqiang Jiang, Dan Zhao, Guozhen He, Shuangli Zhou, Shiqing Han(通讯作者),Transition-Metal-Free TEMPO Catalyzed Aerobic Oxidation of Alcohols to Carbonyls Using an Efficient Br2 Equivalent under Mild Conditions, Chinese Journal of Chemistry, 2013, 31, 794-798. Huiqing Yin, Ming Jin, Wei Chen, Chen Chen, Likang Zheng, Ping Wei and Shiqing Han(通讯作者), Solvent-free Copper-catalyzed N-Arylation of Amino Alcohols and Diamines with Aryl Halides, Tetrahedron Lett. 2012, 53(10), 1265-1270. Jingxian Zhang, Huiqing Yin, Shiqing Han(通讯作者), Copper-Catalyzed N-Arylations of Nitrogen-Containing Heterocycles in Water, Chin. J. Org. Chem., 2012, 32(8), 1429-1433. Jingxian Zhang, Rui Zhang, Bin Tao, Shiqing Han(通讯作者), George Li, Preparation of novel pyridazine-4-boronic acid pinacol esters and imidazole-4-boronic acid pinacol esters through palladium-catalyzed cross-coupling reactions, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244, 625-ORGN. Xinyu Li, Cheng Li, Wenjing Zhang, Xiang Lu, Shiqing Han, and Ran Hong﹡, Highly Stereoselective 7-Endo-Trig/Ring Contraction Cascade To Construct Pyrrolo[1,2-a] quinoline Derivatives, Org. Lett. 2010, 12(8), 1696-1699. Yi Hu, Ping Wei, He Huang, Shi-Qing Han and Ping-Kai Ouyang, Microwave-Assisted Gewald Synthesis of 2-Aminothiophenes using Functional Ionic Liquid as Soluble Support. Heterocycles, 2006, 68(2), 375-380. Yi Hu, Ping Wei, He Huang, Shi-Qing Han and Ping-Kai Ouyang, Synthesis of 2-aminothiophenes on ionic liquid phase support using the gewald reaction, Synthetic Communications, 2006, 36 (11), 1543-1548.