个人简介
招生专业
070703-海洋生物学
086000-生物与医药
招生方向
鱼类免疫及病害防治
教育背景
2012-09--2015-07 中国科学院大学海洋研究所 博士学位
2009-09--2012-03 宁波大学 硕士学位
2005-09--2009-07 天津师范大学 学士学位
工作简历
2018-11~2019-06,University of Maryland, Visiting scholar
2018-01~现在, 中国科学院海洋研究所, 副研究员
2017-07~2017-12,中国科学院海洋研究所, 助理研究员
2015-07~2017-07,中国科学院海洋研究所, 博士后
2012-09~2015-07,中国科学院大学海洋研究所, 博士学位
2009-09~2012-03,宁波大学, 硕士学位
2005-09~2009-07,天津师范大学, 学士学位
奖励信息
(1) 第六届中国科学院沈阳分院优秀青年科技人才奖, 一等奖, 院级, 2018
(2) 中国科学院青年创新促进会, 特等奖, 院级, 2017
(3) 中国科学院海洋研究所汇泉青年学者, 特等奖, 研究所(学校), 2017
(4) 中国科学院优秀博士学位论文, 特等奖, 院级, 2016
(5) 国家海洋局海洋科学技术奖, 一等奖, 部委级, 2016
(6) 中国科学院院长优秀奖, 一等奖, 院级, 2015
(7) 博士研究生国家奖学金, 特等奖, 国家级, 2013
专利成果
( 1 ) 一种C-反应蛋白及其制备和应用, 2014, 第 2 作者, 专利号: CN 103012576 B
( 2 ) 一种鱼类肿瘤坏死因子家族蛋白的重组蛋白及其应用, 2015, 第 1 作者, 专利号: 105175529A
( 3 ) 迟缓爱德华氏菌重组蛋白疫苗及其制备和应用, 2014, 第 2 作者, 专利号: CN 102614503 B
( 4 ) 一种海豚链球菌细菌素及其应用, 2015, 第 2 作者, 专利号: CN 103804475 A
( 5 ) 一种二型肽聚糖识别蛋白及其制备和应用, 2013, 第 2 作者, 专利号: 103131686 A
( 6 ) 大菱鲆CD83分子作为疫苗佐剂的应用, 2015, 第 2 作者, 专利号: 104689313A
( 7 ) 半滑舌鳎补体成分C5a的重组蛋白及其应用, 2019, 第 1 作者, 专利号: CN201610100997
( 8 ) 一种鱼类MBL相关丝氨酸蛋白酶的重组蛋白及其应用, 2019, 第 1 作者, 专利号: CN201610305025
( 9 ) 一种补体丝氨酸蛋白酶的应用, 2020, 第 1 作者, 专利号: 110787289A
科研项目
( 1 ) 中国科学院青年创新促进会基金, 主持, 部委级, 2017-01--2020-12
( 2 ) 中国科学院海洋研究所汇泉青年学者, 主持, 市地级, 2018-01--2020-12
( 3 ) 海水病原的毒力特征研究, 主持, 国家级, 2018-12--2022-12
( 4 ) 迟缓爱德华氏菌与补体分子C3的相互作用及其对补体激活的影响, 主持, 国家级, 2020-01--2023-12
参与会议
(1)The teleost complement factors involved in the regulation of complement activation and immune cell activity 第一届亚洲发育与比较免疫学大会回执 2019-11-01
近期论文
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(1) The trypsin-like serine protease domain of Paralichthys olivaceus complementfactor I regulates complement activation and inhibits bacterial growth, Fish and Shellfish Immunology, 2020, 第 3 作者
(2) Edwardsiella tarda Sip2: A serum-induced protein that is essential to serum survival, acid resistance, intracellular replication, and host infection., Frontiers in Microbiology, 2018, 第 1 作者
(3) Characterization of a teleost membrane-associated protein that is involved in the regulation of complement activation and bacterial infection, Developmental and Comparative Immunology, 2018, 第 1 作者
(4) A teleost CD46 is involved in the regulation of complement activation and pathogen infection, Scientific Reports, 2017, 第 1 作者
(5) CsMAP34, a teleost MAP with dual role: A promoter of MASP-assisted complement activation and a regulator of immune cell activity, Scientific Reports, 2016, 第 1 作者
(6) C5a of Cynoglossus semilaevis has anaphylatoxin-like properties and promotes antibacterial and antiviral defense, Developmental and Comparative Immunology, 2016, 第 1 作者
(7) CsTNF1, a teleost tumor necrosis factor that promotes antibacterial and antiviral immune defense in a manner that depends on the conserved receptor binding site, Developmental and Comparative Immunology, 2016, 第 1 作者
(8) CD83 is required for the induction of protective immunity by a DNA vaccine in a teleost model, Developmental and Comparative Immunology, 2015, 第 1 作者
(9) Edwardsiella tarda evades serum killing by preventing complement activation via the alternative pathway, Fish & Shellfish Immunology, 2015, 第 1 作者
(10) Edwardsiella tarda MliC, a lysozyme inhibitor that participates in pathogenesis in a manner that parallels ivy, Infection and Immunity, 2015, 第 1 作者
(11) Molecular characterization and expression analysis of nine CC chemokines in half-smooth tongue sole, Cynoglossus semilaevis, Fish & Shellfish Immunology, 2015, 通讯作者
(12) ORF75 of megalocytivirus RBIV-C1: A global transcription regulator and an effective vaccine candidate, Fish & Shellfish Immunology, 2015, 通讯作者
(13) A CCL21 chemokine of tongue sole (Cynoglossus semilaevis) promotes host resistance against bacterial infection, Fish & Shellfish Immunology, 2015, 通讯作者
(14) Sil: A Streptococcus iniae bacteriocin with dual role as an antimicrobial and an immunomodulator that inhibits innate immune response and promotes S. iniae infection, PloS One, 2014, 第 1 作者
(15) NKLP27: A teleost NK-lysin peptide that modulates immune response, induces degradation of bacterial DNA, and inhibits bacterial and viral infection, PloS One, 2014, 第 1 作者
(16) The C-reactive protein of tongue sole Cynoglossus semilaevis is an acute phase protein that interacts with bacterial pathogens and stimulates the antibacterial activity of peripheral blood leukocytes, Fish & Shellfish Immunology, 2013, 第 1 作者
(17) First characterization of a teleost Epstein-Barr virus-induced gene 3(EBI3) reveals a regulatory effect of EBI3 on the innate immune response of peripheral blood leukocytes, Developmental and Comparative Immunology, 2013, 第 1 作者
(18) CsTrx80, a truncated form of thioredoxin, possesses chemokine-like property and enhances the immune defense of Cynoglossus semilaevis against bacterial infection, Fish & Shellfish Immunology, 2013, 第 1 作者
(19) Inv1: An Edwardsiella tarda invasin and a protective immunogen that is required for host infection, Fish & Shellfish Immunology, 2012, 第 1 作者
(20) A peptidoglycan recognition protein from Sciaenops ocellatus is a zinc amidase and a bactericide with a substrate range limited to Gram-positive bacteria, Fish & Shellfish Immunology, 2012, 第 1 作者
(21) A pathogenic Vibrio harveyi lineage causes recurrent disease outbreaks in cultured Japanese flounder (Paralichthys olivaceus) and induces apoptosis in host cells, Aquaculture, 2011, 第 1 作者