个人简介
教育工作经历:
2012/10 至今 福州大学,助理研究员
2007/09-2012/07 南开大学,高分子化学与物理,博士
2003/09-2007/07 辽宁大学,应用化学,学士
教学简介:
药物传递系统,功能高分子材料,药物生物技术,生物医学工程综合实验
科研简介:
主要从事生物医用材料研究领域的工作,研究涉及抗菌材料、纳米材料、高分子水凝胶、药物控/缓释载体系统等。目前主持国家自然科学基金青年项目1项,天津大学-福州大学自主创新基金1项,福建省自然科学基金面上项目1项。在ACS Applied Materials & Interfaces,Journal of Controlled Release,International Journal of Biological Macromolecules和Journal of Materials Chemistry B等期刊上发表SCI收录的论文多篇。以第一发明人获得国家知识产权局授权发明专利3项。
科研项目:
1.天津大学-福州大学自主创新基金,细菌微环境响应性自愈合水凝胶的制备及其促进糖尿病足创面修复机制研究,主持。
2.国家自然科学基金青年项目,构筑细菌微环境响应性自愈合水凝胶多重促进糖尿病足创面修复研究,主持。
3.福建省自然科学基金面上项目,多糖基原位凝胶的绿色制备及其用于顺铂控释给药系统的研究,主持。
授权专利:
1. 程翠, 张秀丽, 游力军, 王家斌, 张其清, 一种双重载药的自愈合水凝胶体系及其制备方法, 2020.05.08, 中国, ZL 201710205888.6
2. 程翠, 张秀丽, 孟亚彬, 章志鸿, 陈景帝, 张其清, 一种基于昆布多糖的纳米凝胶及其制备方法, 2019.01.22, 中国, ZL201611121295.3
3. 程翠, 夏丹丹, 张秀丽, 陈立, 张其清, 一种负载铂类药物的水凝胶体系及其制备方法, 2017.8.25, 中国, ZL201510034796.7
获奖情况:
2018年获得厦航奖教金。
近期论文
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代表性论文:
1. Shengcan Guan#, Ya Li#, Cui Cheng*, Xiaoran Gao, Xiaofeng Gu, Xiao Han*, Hanhui Ye*. Manufacture of pH- and HAase- responsive hydrogels with on-demand and continuous antibacterial activity for full-thickness wound healing. International Journal of Biological Macromolecules, 2020, 164, 2418-2431.
2. Li Chen, Wang, Siyuan Wang, Qinying Liu*, Zhihong Zhang, Shaofeng Lin, Qiuhong Zheng, Miaomiao Cheng, Yuying Li, Cui Cheng*. Reduction sensitive nanocarriers mPEG-g-γ-PGA/SSBPEI@siRNA for effective targeted delivery of survivin siRNA against NSCLC. Colloids and surfaces B: Biointerfaces, 2020, 193:111105. (if=4.389)
3. Ya Li#, Cui Cheng#*, Xiaoran Gao, Siyuan Wang, Hanhui Ye,* Xiao Han*. Aminoglycoside hydrogels based on dynamic covalent bonds with pH sensitivity, biocompatibility, self-healing, and antibacterial ability. Journal of Applied Polymer Science, 2020, 137 (41): e49250.
4. CuiCheng, Zhihong Zhang, Siyuan Wang, Li Chen*, Qinying Liu*. Reduction sensitive CC9-PEG-SSBPEI/miR-148b nanoparticles: synthesis, characterization, targeting delivery and application for anti-metastasis. Colloids and Surfaces B: Biointerfaces, 2019: 110412.
5. Cui Cheng#*, Yabin Meng#, Zhihong Zhang, Ya Li, Qiqing Zhang*. Tumoral acidic pH-responsive cis-diaminodichloroplatinum-incorporated Cy5.5-PEG-g-A-HA nanoparticles for targeting delivery of CDDP against cervical cancer. ACS applied materials & interfaces, 2018, 10 (32), 26882-26892.
6. Cui Cheng#*, Yabin Meng#, Zhihong Zhang, Ya Li, Chun Liu, Qiqing Zhang*, pH responsible and fluorescent Cy5.5-PEG-g-A-HA/CDDP complex nanoparticles: synthesis, characterization, and application for targeted drug delivery, Journal of Materials Science: Materials in Medicine: 2019, 30 (6): 58.
7. Cui Cheng#*, Xiuli Zhang#, Yabin Meng, Li Chen, Qiqing Zhang*. Development of a dual drug-loaded hydrogel delivery system for enhanced cancer therapy: in situ formation, degradation and synergistic antitumor efficiency. Journal of Materials Chemistry B, 2017, 5, 8487-8497.
8. Cui Cheng#*, Xiuli Zhang#, Yabin Meng, Zhihong Zhang, Jingdi Chen, Qiqing Zhang* Multiresponsive and biocompatible self-healing hydrogel: its facile synthesis in water, characterization and properties. Soft Matter, 2017, 13, 3003-3012.
9. Cui Cheng, Xiuli Zhang, Yabin Meng, Qiqing Zhang*, In situ forming polysaccharide based self-healing hydrogels for controlled release of cisplatin, Journal of Controlled Release, 2017, 259, e21-e22
10. Cui Cheng#*, Dandan Xia#, Xiuli Zhang, Li Chen, Qiqing Zhang*. Biocompatible poly (N-isopropylacrylamide)-g-carboxymethyl chitosan hydrogels as carriers for sustained release of cisplatin, Journal of Materials Science, 2015, 50(14): 4914-4925.