个人简介
学术兼职
江苏省高校医药教育研究会副理事长
中国药学会应用药理学会常务理事
江苏省药理学会常务理事
药学核心期刊《中国临床药理学与治疗学》、《中华男科学杂志》编委
江苏省食品药品监督管理局新药审评与现场核查专家
教育简历
美国纽约州立大学布法罗分校（State University of New York at Buffalo）博士后；
中国药科大学药理学博士
研究领域
药理学、药物动力学、代谢组学。
在基础研究领域着重于各类新药的临床前与临床的药物动力学、药效学筛选、药理学机制靶点、药效-药动学模型研究，以及骨质疏松症、高脂血症等重大疾病的代谢组学研究
近期论文
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Diketopyrrolopyrrole–Triphenylamine Organic Nanoparticles as Multifunctional Reagents for Photoacoustic Imaging-Guided Photodynamic/Photothermal Synergistic Tumor Therapy [J]. ACS Nano, 2017, 11 (1): 1054–1063
Small-molecule diketopyrrolopyrrole-based therapeutic nanoparticles for photoacoustic imaging-guided photothermal therapy [J]. Nano Research, 2017, 10 (3): 794-801
Aza-Bodipy Photosensitizer for Photoacoustic and Photothermal Imaging Guided Dual Modal Cancer Phototherapy [J]. Journal of Materials Chemistry B, 2017, 5(8):1566-1573.
Synthesis and preclinical pharmacokinetic study of DHA-10, a novel potential antifungal pogostone analogue [J]. Journal of Pharmacy and Pharmacology, 2017, 69 (9): 1084-1090
Metabonomic analysis of fatty acids in seminal plasma between healthy and asthenozoospermic men based on gas chromatography mass spectrometry [J]. Andrologia, 2017, 49 (9): e12744.
Tumor-targeting, enzyme-activated nanoparticles for simultaneous cancer diagnosis and photodynamic therapy [J]. Journal of Materials Chemistry B, 2016, 4(1): 113-120.
Bromo-substituted diketopyrrolopyrrole derivative with specific targeting and high efficiency for photodynamic therapy [J]. ACS applied materials & interfaces, 2016, 8(17): 10737-10742.
Association between the metabolome and bone mineral density in pre-and post-menopausal Chinese women using GC-MS [J]. Molecular BioSystems, 2016, 12(7): 2265-2275
A Thienyl‐Substituted Diketopyrrolopyrrole Derivative with Efficient Reactive Oxygen Species Generation for Photodynamic Therapy [J]. ChemPlusChem, 2016, 81(6): 515-520.
Diketopyrrolopyrrole Derivatives Grafting Hyaluronic Acid for Targeted Photodynamic Therapy [J]. ChemistrySelect, 2016, 1(12): 3071-3074.
Wnt/β-catenin signaling plays an important role in the protective effects of FDP-Sr against oxidative stress induced apoptosis in MC3T3-E1 cell [J]. Bioorganic & Medicinal Chemistry Letters, 2016, 26(19): 4720-4723.
Triptolide disrupts fatty acids and peroxisome proliferator-activated receptor (PPAR) levels in male mice testes followed by testicular injury: a GC–MS based metabolomics study [J]. Toxicology, 2015, 336: 84-95.
Strontium fructose 1, 6‐diphosphate alleviate cyclophosphamide‐induced oligozoospermia by improving antioxidant and inhibiting testicular apoptosis via FAS/FASL pathway [J]. Andrologia, 2015, 47(9): 995-1003.
Pharmacokinetics and tissue distribution of Aucubin, Ajugol and Catalpol in rats using a validated simultaneous LC-ESI-MS/MS assay.[J]. Journal of Chromatography B, 2015, 1002:245-253.
A pre-clinical pharmacokinetic study in rats of three naturally occurring iridoid glycosides, Picroside-I, II and III, using a validated simultaneous HPLC–MS/MS assay[J]. Journal of Chromatography B, 2015, 993: 47-59.
Quantitative analysis of tenuifolin concentrations in rat plasma and tissue using LC-MS/MS: Application to pharmacokinetic and tissue distribution study [J]. Journal of pharmaceutical and biomedical analysis, 2014, 88: 191-200.
Simultaneous determination of osthole, bergapten and isopimpinellin in rat plasma and tissues by liquid chromatography–tandem mass spectrometry [J]. Journal of Chromatography B, 2014, 970: 77-85.
Metabolomic analysis of simvastatin and fenofibrate intervention in high-lipid diet-induced hyperlipidemia rats [J]. Acta Pharmacologica Sinica, 2014, 35(10): 1265-1273.
Comparative pharmacokinetics with single substances and Semen Cuscutae extract after oral administration and intravenous administration Semen Cuscutae extract and single hyperoside and astragalin to rats [J]. Analytical Methods, 2014, 6(18): 7250-7259.
Metabolomic profiles delineate signature metabolic shifts during estrogen deficiency-induced bone loss in rat by GC-TOF/MS [J]. PLoS One, 2013, 8(2): e54965.
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