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研究领域

(1) 室温荧光纳米材料的制备及其生化传感应用: 发展纳米材料与纳米结构的制备新方法,探索纳米生物学效应,系统建立纳米尺度生化分析的新原理与方法 (2) 基于核酸适配体的靶向成像和治疗: 以核酸适配体特异性识别,构建细胞与活体水平的纳米示踪、检测、载药的共性方法与技术 (3) 针对神经性疾病相关标志物的荧光比色检测:主要是帕金森病和阿尔茨海默病

近期论文

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Fenghua Geng, Changpeng Zou, Jinhua Liu,* Xueying Guo, Yunchang Fan,* Haidong Yu, Sheng Yang, Zhipeng Liu,* Lin Li, Development of luminescent nanoswitch for sensing of alkaline phosphatase in human serum based on Al3+-PPi interaction and Cu NCs with AIE properties, Analytica Chimica Acta, 2019,1076, 131-137. Can Chen, Fenghua Geng, Yongxiang Wang,* Haidong Yu, Lin Li, Sheng Yang, Jinhua Liu,* Wei Huang, Design of a nanoswitch for sequentially multi-species assay based on competitive interaction between DNA-templated fluorescent copper nanoparticles, Cr3+ and pyrophosphate and ALP, Talanta, 2019, 205, 120132. Chengxi an Zhu, Lei Gao, Yaojie Han, QiRan OuYang , Lijun Zong, Lin Li, Chengwu Zhang, Jinhua Liu, Hai-Dong Yu*, Wei Huang, Using magnetic levitation for density-based detection of cooking oils, RSC Adv., 2019, 9,18285-18291. Xueying Guo, Lijun Zong,Yucui Jiao,Yufeng Han, Xiaopan Zhang, Jia Xu, Lin Li, Cheng-wu Zhang, Zhipeng Liu, Qiang Ju, Jinhua Liu,* Zhihui Xu,* Hai-Dong Yu,* Wei Huang*, Signal-Enhanced Detection of Multiplexed Cardiac Biomarkers by a Paper-Based Fluorogenic Immunodevice Integrated with Zinc Oxide Nanowires, Anal. Chem. 2019, 91,9300-9307. Lei Gao, Chengxian Zhu, Lin Li, Chengwu Zhang, Jinhua Liu,* Hai-Dong Yu,* Wei Huang*, All paper-based flexible and wearable piezoresistive pressure sensor, ACS Appl. Mater. Interfaces, 2019, 11,25034-25042. Can Chen, Shiyu Zhang, Chengwu Zhang, Lin Li, Jixin Zhu, Jinhua Liu*, TMB-assembly as nanosubstrate construction colorimetric kit for highly sensitive and selective detection of H2O2 and monoamine oxidase-A based on Fenton reaction, Microchemical Journal, 2019, 150,104177. Xiaofei Qin, Can Chen, Shiyu Zhang, Jixin Zhu, Yongxiang Wang, Jinhua Liu*, Near-infrared emission TMB dots as colorimetric and fluorescent nanoswitch for reversible recognition of iron ion and cysteine and its logic gate application, Analytical Methods, 2019, DOI: 10.1039/C9AY01749F. Lijun Zong, Yucui Jiao, Xueying Guo, Chengxian Zhu, Lei Gao, Yufeng Han, Lin Li, Chengwu Zhang, Zhipeng Liu, Jinhua Liu, Qiang Ju, Hai-Dong Yu,* Wei Huang, Paper-based fluorescent immunoassay for highly sensitive and selective detection of norfloxacin in milk at picogram level, Talanta, 2019,195, 333-338. Yi Liu, Lei Bai, Yihao Li, Yun Ni, Chenqi Xin, Chengwu Zhang, Jinhua Liu, Zhipeng Liu, * Lin Li, * Wei Huang, Visualizing hydrogen peroxide in Parkinson’ s disease models via a ratiometric NIR fluorogenic probe, Sensor Actuat B: Chem.,2019, 279, 38-43. qiaoqiao Ci, Jinhua Liu, * Xiaofei Qin, Linqi Han, Hai Li, Hai-Dong Yu, Kah-Leong Lim, Cheng-wu Zhang, * Lin Li,* Wei Huang, Polydopamine dots-based fluorescent nanoswitch assay for reversible recognition of glutamic acid and Al3+ in human serum and living cell, ACS Appl. Mater. Interfaces, 2018, DOI: 10.1021/acsami.8b12087 Shiyu Zhang, #Can Chen, # Xiaofei Qin, Qianchen Zhang, Jinhua Liu,* Jixin Zhu, Yongqian Gao, Lin Li, Wei Huang, Ultrasensitive detection of trypsin activity and inhibitor screening based on the electron transfer between phosphorescence copper nanocluster and cytochrome c, Talanta, 2018, 189, 92-99. Qianchen Zhang, # Shiyu Zhang, # Jinhua Liu,* Jixin Zhu, Chengwu Zhang, Yun Ni, Yongqian Gao, Haidong Yu, Lin Li, * Wei Huang, Surface oxidation -controlled synthesis of blue fluorescence wavelength-tunable mini-size carbon nitride nanosheet and its application, ChemistrySelect, 2018, 3,2229-2234. Qianchen Zhang, Duoduo Zhao, Chengwu Zhang, Jinhua Liu,* Zhongfu An, Xiaofei Qin, Yongqian Gao,* Shiyu Zhang, Lin Li,* Wei Huang. An effective signal amplifying strategy for copper (II) sensing by using in situ fluorescent proteins as energy donor of FRET. Sensor Actuat B: Chem., 2018, 259, 633-641. Desheng Li, Dongya Wang, Kun Rui, Zhongyuan Ma, Ling Xie, Jinhua Liu, Yu Zhang,∗ Runfeng Chen, Yan Yan, Huijuan Lin, Xiaoji Xie,∗, Jixin Zhu,∗ Wei Huang. Flexible phosphorus doped carbon nanosheets/nanofibers: Electrospun preparation and enhanced Li-storage properties as free-standing anodes for lithium ion batteries. Journal of Power Sources. 2018, 384, 27-33 Linqi Han,#Riri Shi, # Chenqi Xin, Qiaoqiao Ci, Jingyan Ge, * Jinhua Liu, Qiong Wu, Chengwu Zhang,* Lin Li,* and Wei Huang. Mitochondrial specific H2Sn fluorogenic probe for live cell imaging by rational utilization of a dual-functional-photocage group. ACS sens. 2018, 3, 1622-1626. Hanlu Yan, Qiuwen Chen, * Jinhua Liu, Yong Feng, Kaimin Shih. Phosphorus recovery through adsorption by layered double hydroxide nano-compo sites and transfer into a struvite-like fertilizer. Water Research. 2018,145, 721-730. Jinhua Liu,* Duoduo Zhao, Lin Li, Minrui Weng, Chengwu Zhang,* Shiyu Zhang, Jixin Zhu,* Yong Feng, Kaimin Shih, Wei Huang. Mini-sized carbon nitride nanosheets with double excitation- and pH-dependent fluorescence behaviors for two-photon cell imaging. Chem. Asian J. 2017, 12,835-840. Jiang X, Geng F, Wang Y*, Liu JH, Qu P, Xu M*;Fluorescence turn-on and colorimetric dual readout assay of glutathione over cysteine based on the fluorescence inner-filter effect of oxidized TMB on TMPyP; Biosensors and Bioelectronics; 81; 268-273;2016. Feng Y, Liu JH, Wang D, Zhou Z, Deng Y, Zhang T, Shih K *; Efficient degradation of sulfamethazine with CuCo2O4 spinel nanocatalysts for peroxymonosulfate activation; Chemical Engineering Journal; 280;514-524; 2015. Liu JH *, Yu J, Chen J, Shih K; "Noncovalent assembly of carbon nanoparticles and aptamer for sensitive detection of ATP"; RSC advance;4; 38199-38205; 2014.

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