个人简介

2013 Kavli Foundation Emerging Leader in Chemistry Lecture 2012 Pittsburgh Conference Achievement Award 2011 Joseph Black Award from the Royal Society of Chemistry 2010 Chemical Society Division of Analytical Chemistry 2010 Alfred P. Sloan Fellow 2009 Camille and Henry Dreyfus Teacher-Scholar 2009 Society for Electroanalytical Chemisty Young Investigator 2008 NIH New Innovator 2007-2009 University of Minnesota McKnight Land-Grant Assistant Professor 2007 Delegate for Japan-U.S. Young Researchers Exchange on Nanotechnology 2006 National Science Foundation CAREER Award 2006 Kinship Foundation Searle Scholar 2006 3M Nontenured Faculty Award 2005 Nobel Laureate Signature Award for Graduate Education in Chemistry from the American Chemical Society 2005 Victor K. LaMer Award from the American Chemical Society Division of Colloid and Surface Science 2004 Ruth L. Kirschstein National Research Service Award Postdoctoral Fellowship from the National Institutes of Health 2003 Award for Excellence in Graduate Research from Northwestern University 2002 Presidential Fellowship from Northwestern University

研究领域

Nanoscience & Materials Chemistry/Analytical & Bioanalytical Chemistry/Chemical Biology/Inorganic & Organometallic Chemistry/Environmental & Green Chemistry/Chemical Physics

The Haynes group focuses on applications of analytical chemistry in the fields of immunology and toxicology, with much expertise in the area of single cell analysis. One major area of interest is nanotoxicology - an emerging field investigating the biological and ecological impacts of engineered nanomaterials. Another major focus in the group is on studying fundamental properties of cells involved in inflammation. In fact, the Haynes group has performed the first ever real-time single blood platelet measurements, examining the chemical messenger molecules that platelets secrete upon stimulation. While most of the Haynes lab research employs electrochemical and spectroscopic techniques, the group is always exploring new and exciting technologies to answer pressing bioanalytical questions.

近期论文

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Imaging Cytoskeleton Dynamics in Drug-treated Platelets, Finkenstaedt-Quinn, S.A., Ge, S., and Haynes, C.L. Anal. Bioanal. Chem., accepted. Analytical Characterization of the Role of Phospholipids in Platelet Adhesion and Secretion, Koseoglu, S., Meyer, A.F., Kim, D., Meyer, B.M., Wang, Y., Dalluge, J., Haynes, C.L. Anal. Chem., 87(1) 413-421 (2015). Enhancing Graduate Student Communication to General Audiences through Blogging about Nanotechnology and Sustainability, Bishop, L., Tillman, A., Geiger, F., Haynes, C.L., Klaper, R., Murphy, C.J., Orr, G., Pedersen, J., DeStefano, L., Hamers, R. J. Chem. Ed., 91(10) 1600-1605 (2014). Accounting for Biological Aggregation in Heating and Imaging of Magnetic Nanoparticles, Etheridge, M.L., Hurley, K.R., Zhang, J., Jeon, S., Ring, H.L., Hogan, C., Haynes, C.L., Garwood, M., and Bischof, J.C. Technology, 2(3) 1-15 (2014). Exploring Inflammatory Disease Drug Effects on Neutrophil Function, Wu, X., Kim, D., Young, A.T., and Haynes, C.L. Analyst, 139(16) 4056 - 4063 (2014). Facile Method to Stain the Bacterial Cell Surface for Super-Resolution Fluorescence Microscopy, Gunsolus, I.L., Hu, D., Mihai, C., Lohse, S.E., Lee, C.-S., Torelli, M.D., Hamers, R.J., Murhpy, C.J., Orr, G., and Haynes, C.L. Analyst, 139(12) 3174-3178 (2014). Microfluidic-SERS Devices for One Shot Limit-of-Detection, Kim, D., Campos,A.R., Datt, A., Gao, Z., Rycenga, M., Burrows, N.D., Greeneltch, N.G., Mirkin, C.A., Murphy, C.J., Van Duyne, R.P., and Haynes, C.L. Analyst, 139(13) 3227-3234 (2014). Rapid and Sensitive in situ SERS Detection using Dielectrophoresis, Cherukulappurath, S., Lee, S., Campos, A., Haynes, C.L., and Oh, S.-H. Chem. Mat., 26(7) 2445-2452 (2014). Microfluidics-based in vivo Mimetic Systems for the Study of Cellular Biology, Kim, D., Wu, X., Young, A.T., and, Haynes, C.L. Acc. Chem. Res., 47(4) 1165-1173 (2014). Activities for Middle School Students To Sleuth a Chemistry “Whodunit” and Investigate the Scientific Method, Meyer, A.F., Knutson, C.M., Finkenstaedt-Quinn, S. A., Gruba, S. M., Meyer, B.M., Thompson, J.W., Maurer-Jones, M.A., Halderman, S., Tillman, A.S., DeStefano, L., Haynes, C.L. J. Chem. Ed., 91(3) 410-413 (2014). Death and Axes': Unexpected Ca2+ Entry Phenologs Predict New Anti-Schistosomal Agents, Chan, J.D., Agbedanu, P.N., Zamanian, M., Gruba, S.M., Haynes, C.L., Day, T.A., Marchant, J.S. PLOS Pathogens, 10(2): e1003942 (2014). Time- and Concentration-Dependent Effects of Exogenous Serotonin and Inflammatory Cytokines on Mast Cell Function, Gruba, S.M., Meyer, A.F., Manning, B.M., Wang, Y., Thompson, J.W., Dalluge, J.J., and Haynes, C.L. ACS Chem. Bio., 9(2) 503-509 (2014). Editorial - Analytical Toxicology of Nanoparticles, Haynes, C.L. Analyst, 139(5) 868-869 (2014). On-chip Evaluation of Platelet Adhesion and Aggregation upon Exposure to Mesoporous Silica Nanoparticles, Kim, D., Finkenstaedt-Quinn, S., Hurley, K., Buchman, J.T., and Haynes, C.L. Analyst, 139(5) 906-913 (2014). On-Chip Evaluation of Neutrophil Activation and Neutrophil-Endothelial Cell Interaction during Neutrophil Chemotaxis, Kim, D. and Haynes, C.L. Anal. Chem., 85(22) 10787-10796 (2013). Re-Examining the Size/Charge Paradigm: Differing In Vivo Characteristics of Size and Charge-Matched Mesoporous Silica Nanoparticles, Townson, J., Lin, Y.-S., Agola, J., Carnes, E., Leong, H.S., Lewis, J., Haynes, C.L., and Brinker, C.J. J. Am. Chem. Soc., 135(43), 16030-16033 (2013). The Role of p38 MAPK in Neutrophil Functions: Single Cell Chemotaxis and Surface Marker Expression, Kim, D. and Haynes, C.L. Analyst, 138, 6826-6833 (2013). Isotope-Dilution UPLC-MS/MS Determination of Cell-Secreted Bioactive Lipids, Meyer, A.F., Thompson, J.T., Wang, Y., Koseoglu, S., Dalluge, J.J., and Haynes, C.L. Analyst, 138(19), 5697 - 5705 (2013). Impact of TiO2 Nanoparticles on Growth, Biofilm Formation, and Flavin Secretion in Shewanella oneidensis, Maurer-Jones, M.A., Gunsolus, I., Meyer, B., Christenson, C., and Haynes, C.L. Analytical Chemistry, 85(12) 5810-5818 (2013). Effects of Mesoporous Silica Coating and Post-Synthetic Treatment on the Transverse Relaxivity of Iron Oxide Nanoparticles, Hurley, K., Lin, Y.-S., Zhang, J., Egger, S., Haynes, C.L. Chemistry of Materials, 25(9) 1968-1978 (2013).