个人简介
鲁康乐,男,1986年生,博士,副教授,硕士生导师。2014年6月毕业于南京农业大学动物营养与饲料科学专业;2014年7月-2015年8月在中国水产科学研究院黄海水产研究所从事博士后研究工作;2015年9月进入集美大学水产学院工作至今。目前主持国家自然科学基金1项,发表研究论文20余篇。
教学情况 (Teaching)
承担课程:动物营养学、水产动物饵料学、营养生理、饲料安全、饲料配方计算机设计等。
科研项目(Research Projects)
1. 蛋白激酶AMPK介导高脂抑制团头鲂肝脏脂肪酸β-氧化的分子机制研究,国家自然科学基金青年基金项目,2017年-2019年,24.8万,主持;
2. 蛋白激酶AMPK介导高脂抑制石斑鱼肝脏线粒体生成的分子机制研究,福建省自然科学基金青年创新项目,2017年-2019年,4万元,主持;
3. 黄连素对石斑鱼生长与脂肪代谢影响的研究,福建省教育厅项目,2017年-2019年,1万元,主持;
4. 基于脂肪酸β-氧化调控通路研究鱼类脂肪肝的发生机制,福建省教育厅杰青项目,2017年-2019年,7万元,主持;
5. 国家海水鱼产业技术体系(海鲈营养需求与饲料),国家现代农业产业技术体系,2017-2020年,280万元,骨干;
6. 石斑鱼健康养殖技术及高效配合饲料的研发和推广应用,福建省科技厅重大专项,2016-2020年,190万元,参与;
7. 牛磺酸影响斜带石斑鱼脂类代谢的分子机制研究,国家自然科学基金面上项目,2018-2021,56万元,参与。
学术交流 (Conferences)
1. 参加首届全国大宗淡水鱼营养与饲料学术研讨会(2011年,合肥);
2. 参加第二届全国大宗淡水鱼营养与饲料学术研讨会(2012年,南京),并做题为“团头鲂营养性脂肪肝模型的建立”学术报告;
3. 参加第三届全国大宗淡水鱼营养与饲料学术研讨会(2013年,杭州),并做题为“高脂日粮对团头鲂肝脏脂肪分泌、脂肪转运和脂肪沉积的影响”学术报告;
4. 参加第四届全国大宗淡水鱼营养与饲料学术研讨会(2014年,武汉),并做题为“团头鲂脂肪代谢的研究进展”学术报告。
获奖与社会兼职 (Others)
1.荣获南京农业大学2014届“优秀毕业博士生”;
2. 荣获2013年度“国家优秀研究生奖学金”;
3. British Journal of Nutrition, Fish and Shellfish Immunology, Aquaculture, Aquaculture Research, Aquaculture Reports, Aquaculture International, Fish Physiology and Biochemistry, Food & nutrition, Food Research International, Frontiers in Physiology, Comparative Biochemistry and Physiology等SCI期刊审稿人(Reviewers),动物营养学报,水产学报,南京农业大学学报,等国内期刊的审稿人;
4. Frontiers in Marine Science 期刊副主编(Guest associate editor),并任Fish Nutrition, Metabolism and Physiology专题的主编(Editor-in-Chief);Frontiers in Physiology期刊编委会Review Editor.
5. 福建省科技厅省级科技特派员
研究领域
1. 水产动物营养与饲料:主要研究脂肪源物质对水产动物生长与健康的影响;
2. 水产动物生理学:主要研究养殖水产动物脂代谢、饲料添加剂对脂代谢紊乱的改善;
3. 水产动物分子营养学:主要研究脂肪营养素对水产动物基因表达的调控作用;
4. 鱼类线粒体营养素的开发:利用细胞生物学等现代技术,研究鱼类线粒体营养的理论,并开发能够改善鱼类线粒体功能的产品。
近期论文
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[16] Lu KL, Tomas Policar, Xiao-jun Song, Samad Rahimnejad. Molecular characterization of PGC-1β (PPAR-gamma coactivator 1β) and its roles in mitochondrial biogenesis in blunt snout bream (Megalobrama amblycephala). International Journal of Molecular Sciences. 2020, 21, 1935; doi:10.3390/ijms21061935
[15] Yang M.Q., Rahimnejad S., Zhang C.X., Song K., Lu KL*(通讯作者), Wang L*. Histomorphology of gastrointestinal tract in bullfrog Rana (Lithobates) catesbeiana and evaluation of the changes induced by a soybean meal‐based diet. Aquaculture Research 2020, 51:164-174 (cover page).
[14] Cai LS, Wang L, Song K, Lu, KL* (通讯作者), Zhang CX*, Rahimnejad S, Evaluation of protein requirement of spotted seabass (Lateolabrax maculatus) under two emperatures, and the liver transcriptome response to thermal stress, Aquaculture, 2020, 51:734615.
[13]. Lu, KL., Samad Rahimnejad, Zhong-Li Ji, Chun-Xiao Zhang. Comparative analysis of vertebral transcriptome in Japanese seabass (Lateolabrax japonicus) fed diets with varying phosphorus/calcium levels. Comparative Biochemistry and Physiology, Part A, 2019, 230: 49–55
[12]. Song X, Rahimnejad S, Zhou W, Cai L and Lu, KL. (通讯作者) Molecular Characterization of Peroxisome Proliferator-Activated Receptor-Gamma Coactivator-1(PGC1) and Its Role in MitochondrialBiogenesis in Blunt Snout Bream(Megalobrama amblycephala).Front. Physiol. 2019, 9:1957.
[11]. Zhou W.H., Rahimnejad S., Lu, KL. (通讯作者), et al., Effects of berberine on growth, liver histology, and expression of lipid-related genes in blunt snout bream (Megalobrama amblycephala) fed high-fat diets Fish Physiol Biochem, 2019, 45:83–91.
[10]. Zhou, W., Rahimnejad, S., Tocher, D. R., Lu, KL. (通讯作者), Zhang, C., & Sun, Y.. Metformin attenuates lipid accumulation in hepatocytes of blunt snout bream (Megalobrama amblycephala) via activation of AMP-activated protein kinase. Aquaculture, 2019, 499, 90-100.
[9]. Zhang C N , Rahimnejad S , Lu K L(通讯作者) , et al. Molecular characterization of p38 MAPK from blunt snout bream (Megalobrama amblycephala) and its expression after ammonia stress, and lipopolysaccharide and bacterial challenge. Fish & Shellfish Immunology, 2019,84, 848–856.
[8]. Lu K L, Ji Z L, Rahimnejad S, et al. De Novo, assembly and characterization of seabass Lateolabrax japonicus, transcriptome and expression of hepatic genes following different dietary phosphorus/calcium levels. Comparative Biochemistry & Physiology Part D Genomics & Proteomics, 2017, 24:51-56.
[7]. Lu, K. L., Wang, L. N., Zhang, D. D., Liu, W. B., Xu, W. N. Berberine attenuates oxidative stress and hepatocytes apoptosis via protecting mitochondria in blunt snout bream megalobramaamblycephala fed high-fat diets. Fish Physiology & Biochemistry, 2017,(43):65–76.
[6]. Lu, K.L.; Zhang D.D.; Wang, L.N.; Xu, W.N.; Liu, W.B. Molecular characterization of carnitinepalmitoyltransferase IA in Megalobramaamblycephala and effects on its expression of feeding status and dietary lipid and berberine . Comparative Biochemistry & Physiology Part B Biochemistry & Molecular Biology, 2016 (191):20-25.
[5]. Lu, K.L.; Xu, W.N.; Liu, W.B.; Wang, L.N.; Zhang, C.N; Li, X.F. Association of Mitochondria dysfunction with Oxidative stress and Immune suppression in Blunt Snout Bream Megalobramaamblycephala fed a high-fat diet. Journal of Aquatic Animal Health, 2014 (26):100-12
[4]. Lu, K.L.; Li, X.F.; Wang, L.N.; Zhang, C.N; Liu, W.B. Effects of Dietary Nutrient Composition on Compensatory Growth of juvenile Blunt snout bream Megalobramaamblycephala. North American Journal of Aquaculture, 2014 (76): 55-60.
[3]. Lu, K.L.; Xu, W.N.; Wang, L.N.; Zhang, D.D.; Liu, W.B.; Zhang, C.N. Hepatic β-oxidation and regulation of carnitinepalmitoyltransferase (CPT) I in blunt snout bream Megalobramaamblycephala fed a high fat diet. PLoS one 2014 9(3): e93135.
[2]. Lu, K.L.; Xu, W.N.; Li, J.Y.; Li, X.F.; Huang, G.Q.; Liu, W.B. Alterations of liver histology and blood biochemistry in blunt snout bream Megalobramaamblycephala fed high-fat diets. Fisheries Science, 2013 (74): 1-11.
[1]. Lu, K.L.; Xu, W.N.; Li, X.F.; Liu, W.B.; Wang, L.N.; Zhang, C.N. Hepatic triacylglycerol secretion, lipid transport and tissue lipid uptake in blunt snout bream (Megalobramaamblycephala) fed high-fat diet. Aquaculture, 2013 (408-409): 160-168.