个人简介
教育背景 NATINOALTAIWAN UNIVERSITY, TAPEI, TAIWAN 1981 Bachelor of Science inBotany 台湾大学植物系学士
UNIVERSITY OF IOWA , IOWA CITY , IA , USA 1991 Ph.D., Microbiology 美国爱荷华大学微生物学博士
工作经历 2011-现在:中国深圳东阳光实业发展有限公司研究院,生物制药首席科学官, 职责:组建研发团队及领导开发生产单克隆抗体仿制药与新药;
2009-2011:美国金思瑞生物技术有限公司生物工程部总监
2008-2009: 美国Laureate Pharma公司 首席科学家, 上游工艺开发主管
1997-2008: 美国先灵葆雅 (默克)公司 首席科学家
近期论文
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Homann,MJ, Suen WC, Zhang N, and Zaks A (2006). In “Biocatalysis in the Pharmaceutical and Biotechnology Industries¨ edited by Ramesh Patel, p 645-660.
Comparative analysis of chemical and biocatalyticalsyntheses of drug intermediates
Zhang N, Daubaras DL, and Suen WC (2005).In “Handbook of Industrial Mycology” edited by Zhiqiang An, Marcel Dekker,p.667-687.
Heterologous protein expression in yeastsand filamentous fungi
Suen WC, Zhang N, Xiao L, Madison V, andZaks A (2004). Protein Engineering, Design, & Selection 17 (2): 133-140.
Improved activity and thermostability ofCandida antarctica lipase B by DNA familyshuffling
Zhang N, Suen WC, Windsor W, Xiao L,Madison V, and Zaks A (2003). Protein Engineering 16 (8): 599-605.
Improved tolerance of Candida antarctica lipase B towards irreversible thermalinactivation through directed evolution