倪芳 - 中国科学技术大学 - 合肥微尺度物质科学国家研究中心

个人简介

教授，博士生导师。2013年于中国科学技术大学生命科学学院获得博士学位，2015年至2019年于美国Emory大学医院从事博士后研究。2019年9月加入中国科学技术大学生命科学与医学部，组建血液免疫学实验室，担任PI。实验室主要围绕生物力学、血液免疫代谢等前沿方向，通过多学科交叉研究，揭示造血/免疫稳态及其失衡的调控机制。近年来研究成果以第一/通讯作者发表在Cell Stem Cell, Nature Metabolism, Nature Biomedical Engineering, Cell Reports Medicine，Genome Medicine等国际学术期刊。教育与科研经历 1998 - 2003 安徽医科大学，临床医学学士 2003 - 2006 安徽医科大学，病理生理学硕士 2009 - 2013 中国科学技术大学，细胞生物学博士 2006 - 2015 安徽医科大学，助教/讲师/副教授 2015 - 2019 美国Emory大学，博士后 2019.9 - 至今中国科学技术大学，特任研究员-青年杰出人才

研究领域

造血调控白血病发生机理 NK细胞发育及功能调控白血病免疫微环境及基于NK细胞的白血病免疫治疗

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Wu M, Yang H, Liu S, Jiang L, Liang T, Wang Y, Zhu M, Song X, Liu H, Shen J, Wang S, Zhu X, Qu CK, Cheng L, Jiang H, Ni F. Enhanced engraftment of human haematopoietic stem cells via mechanical remodelling mediated by the corticotropin-releasing hormone.Nat Biomedical Engineering. 2024 Dec 23. doi: 10.1038/s41551-024-01316-1. 2. Wang Y, Huang B, Liang T, Jiang L, Wu M, Liu X, Zhu M, Song X, Zhao N, Wei H, Zheng C, Ni F. Venetoclax acts as an immunometabolic modulator to potentiate adoptive NK cell immunotherapy against leukemia. Cell Reports Medicine. 2024 May 21:101580. 3. Guo C, Wu M, Huang B, Zhao R, Jin L, Fu B, Wang P, Wang D, Zheng M, Fang J, Wei H, Qu K, Ni F. Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19. Genome Medicine. 2022 May 3;14(1):46. 4. Ni F, Yu WM, Wang XY, Fay ME, Young KM, Qiu YZ, Lam WA, Sulchek TA, Cheng T, Scadden DT, and Qu CK. Ptpn21 controls hematopoietic stem cell homeostasis and biomechanics. Cell Stem Cell.2019 Apr 4; 24(4):608-620.e6. 5. Ni F, Yu WM, Li ZG, Graham DK, Jin LT, Kang S, Rossi MR, Li SY, Broxmeyer HE, and Qu CK. Critical role of ASCT2-mediated amino acid metabolism in promoting leukeamia development and progression. Nature Metabolism. 2019 Mar;1(3):390-403 Guo C#, Wu M#, Huang B#, Zhao R, Jin L, Fu B, Wang P, Wang D, Zheng M, Fang J, Wei H*, Qu K*, Ni F*. Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19. Genome Med, 2022; 14(1):46. Hu L#,Ni F#, Wang XY, Fay ME, Lam WA, Sulchek TA, and Qu CK*. Decreased cell stiffness enhances leukemia development and progression.Leukemia, 2020; 34, 2493–2497. Ni F, Yu WM, Wang XY, Fay ME, Young KM, Qiu YZ, Lam WA, Sulchek TA, Cheng T, Scadden DT, and Qu CK*. Ptpn21 controls hematopoietic stem cell homeostasis and biomechanics. Cell Stem Cell, 2019; 24(4):608-620.e6. Ni F, YuWM, Li ZG, GrahamDK, JinLT, Kang S, RossiMR, LiSY, BroxmeyerHE, and Qu CK*. Critical role of ASCT2-mediated amino acid metabolism in promoting leukeamia development and progression. Nature Metabolism, 2019;1(3):390-403. Ni F, Sun R, Fu B, Wang F, Guo C, Tian Z*, Wei H*.IGF-1 promotes the development and cytotoxic activity of human NK cells.Nature Communications, 2013; 4:1479.