个人简介

2004年毕业于哈尔滨医科大学药学院药学系，2010年获北京协和医学院基础医学研究所细胞生物学博士学位。现任中国医学科学院药用植物研究所药理毒理中心副研究员。

研究领域

1. 中药心血管药理学方向：应用多种动物及细胞模型开展中药复方及其有效成分药理作用及机制的研究。 2. 心血管疾病发病机理：着重从肥胖、糖尿病及心血管疾病系统中的关键基因及蛋白质分子入手，探讨药物-基因-疾病间的网络关联。

心血管药理学

近期论文

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1.Bing Sun*, Jing Xiao, Xiao-Bo Sun*, and Ying Wu. Notoginsenoside R1 attenuates cardiac dysfunction in endotoxemic mice: an insight into estrogen receptor activation and PI3K/Akt signaling. British Journal of Pharmacology, 168(7), 1758-1770, 2013. (IF=5.0)（通讯作者） 2.Jing Xiao, Bing Sun, Ming Li, Ying Wu, and Xiao-Bo Sun*. A novel adipocytokine visfatin protects against H2O2-induced myocardial apoptosis: A missing link between obesity and cardiovascular disease. Journal of Cellular Physiology, 228(3), 495-501, 2013. (IF=4.2) （并列第一作者） 3.Bing Sun, Gui-Bo Sun, Jing Xiao, Rong-Chang Chen, Xin Wang, Ying Wu, Li Cao, Zhi-Hong Yang, Xiao-Bo Sun*. Isorhamnetin Inhibits H2O2-Induced Activation of the Intrinsic Apoptotic Pathway in H9c2 Cardiomyocytes Through Scavenging Reactive Oxygen Species and ERK Inactivation. Journal of Cellular Biochemistry, 113(2):473-485, 2012. (IF=3.1) 4.Bing Sun, Nan Qi, Tao Shang, Hui Wu, Ting-Ting Deng, Dai-Shu Han*. Sertoli cell-initiated testicular innate immune response through toll-like receptor-3 activation is negatively regulated by Tyro3, Axl, and mer receptors. Endocrinology, 151(6):2886-2897, 2010. (IF=5.2) 5.Jing Xiao, Gui-Bo Sun, Bing Sun, Ying Wu, Ling He, Xin Wang, Rong-Chang Chen, Li Cao, Xiao-Yu Ren, Xiao-Bo Sun*. Kaempferol protects against doxorubicin-induced cardiotoxicity in vivo and in vitro. Toxicology, 292 (1): 53–62, 2012. (IF=4.0) 6.Jing Xiao, Bing Sun, Guo-Ping Cai*. Transient expression of interferon-inducible p204 in the early stage is required for adipogenesis in 3T3-L1 cells. Endocrinology, 151(7):3141-3153, 2010. (IF=5.2) 7.Jing Xiao, Nai-Li Wang, Bing Sun, Guo-Ping Cai*. Estrogen receptor mediates the effects of pseudoprotodiocsin on adipogenesis in 3T3-L1 cells. Am J Physiol Cell Physiol, 299(1):C128-C138, 2010. (IF=4.2) 8.Tao Shang, Xiaoyan Zhang, Tao Wang, Bing Sun, Ting-Ting Deng, Dai-shu Han*. Toll-like receptor-initiated testicular innate immune responses in mouse Leydig cells. Endocrinology, 152(7): 2827-2836, 2011. (IF=5.2) 9.孙冰，韩代书*。Toll样受体信号通路的负调控。生物化学与生物物理进展，第36卷，第12期，1516-1522页，2009。 10.吴颖，孙冰，肖静，等。三七皂苷R1对LPS诱导的小鼠心肌损伤的保护作用。中国药理学通报，第2期，179-184页，2013。