个人简介
2006年获日本香川大学医学部医学博士学位,中国医学科学院药物研究所药理中心博士后,2009年至中国医学科学院药用植物研究所药理毒理中心工作。
研究领域
1.中药及天然产物治疗高脂血症药理药效及其分子机理研究
2.中药及天然产物调节糖尿病药理药效及其分子机理研究
3.中药及天然产物改善动脉粥样硬化药理药效及其分子机理研究
4.天然产物作用靶点发现研究
5.中药、民族药及功能食品的研发
心脑血管药理学
近期论文
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2. Juan Chen, Hui Wang, Shun-xing Guo. 2012. Isolation and identification of endophytic and mycorrhizal fungi from seed and root of Dendrobium (Orchidaceae) Mycorrhiza 22:297–307. 1. Sun J, Sun G, Meng X, Wang H, Luo Y, Qin M, Ma B, Wang M, Cai D, Guo P, Sun X.Isorhamnetin Protects against Doxorubicin-Induced Cardiotoxicity In Vivo and In Vitro.PLoS One. 2013 May 28;8(5):e64526.
2. Xiaopo Zhang, Chongming Wu, Haifeng Wu, Linghui Sheng, Yan Su, Xue Zhang, Hong Luan, Guibo Sun, Xiaobo Sun, Yu Tian, Yubin Ji, Peng Guo, Xudong Xu. Antihyperlipidemic effects and the potential mechanisms of action of the caffeoylquinic acids-rich Pandanus tectorius fruits extract in hamsters fed a high fat-diet. PLoS One. 2013 Apr 16;8(4):e61922. (通讯作者)
3. Xiaopo Zhang, Peng Guo, Guangli Sun, Shilin Chen, Meihua Yang, Naiguang Fu, Haifeng Wu, Xudong Xu**. Phenolic compounds and flavonoids from the fruits of Pandanus tectorius Soland. J. Med. Plants. Res., 2012,6 (13): 2622-2624.
4. Guo P, Lian ZQ, Sheng LH, Wu CM, Gao J, Li J, Wang Y, Guo YS, Zhu HB. The adenosine derivative 2',3',5'-tri-O-acetyl-N6-(3-hydroxylaniline) adenosine activates AMPK and regulates lipid metabolism in vitro and in vivo. Life Sci. 2012 Jan 2;90(1-2):1-7.
5. Guo P, Wu C, Masaki T, Mori H, Nishiyama A.Subdose of fasudil suppresses myocardial fibrosis in aldosterone-salt-treated uninephrectomized rats. Pharmazie. 2011 Sep;66(9):716-9.
6. Yang R, Guo P, Song X, Liu F, Gao N**. Hyperlipidemic guinea pig model: mechanisms of triglyceride metabolism disorder and comparison to rat. Biol Pharm Bull. 2011,34(7):1046-51. (并列第一作者)
7. Guo P, Kai Q, Gao J, Lian ZQ, Wu CM, Wu CA, Zhu HB. Cordycepin prevents hyperlipidemia in hamsters fed a high-fat diet via activation of AMP-activated protein kinase. J Pharmacol Sci. 2010;113(4):395-403.