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个人简介

1998年毕业于中国协和医科大学药物化学专业获理学博士学位,2003年赴美国西奈山医学院开展博士后和合作研究2年。现任中国医学科学院北京协和医学院药用植物研究所天然药物化学中心常务副主任。

研究领域

1. 基于代谢组学的中药及其复方物质基础及作用机理研究 2. 结构新颖的活性天然产物的发现和结构修饰

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.Jia HM, Li Q, Zhou C, Yu M, Yang Y, Zhang HW, Ding G, Shang H, Zou ZM*. Chronic unpredictive mild stress leads to altered hepatic metabolic profile and gene expression.Sci Rep. 2016, 6:23441. 2.Zhang T, Si JG, Zhang QB, Ding G, Zou ZM*. New Highly Oxygenated Germacranolides from Carpesium divaricatum and their Cytotoxic Activity. Sci Rep. 2016, 6:27237. 3.Zhou C, Jia HM, Liu YT, Yu M, Chang X, Ba YM,Zou ZM*. Metabolism of Glycerophospholipid, Bile Acid and Retinol Are Correlated with the Early Outcomes of Autoimmune Hepatitis. Mol. BioSyst. 2016,12(5):1574-85 4.Sun ZJ, Jia HM, Qiu GX, Zhou C, Guo S, Zhang JG, Shen JX, Zhao Y*, Zou ZM*..Identification of candidate diagnostic biomarkers for adolescent idiopathic scoliosis using UPLC/QTOF-MS analysis: a first report of lipid metabolism profiles. Sci Rep. 2016, 6:22274. 5.Yu M, Cui FX, Jia HM, Zhou C, Yang Y, Zhang HW, Ding G, Zou ZM*. Aberrant purine metabolism in allergic asthma revealed by plasma metabolomics. J Pharm Biomed Anal. 2016,120:181-9. 6.Chang X, Jia HM, Zhou C, Zhang HW, Yu M, Yang JS, Zou ZM*. Role of Bai-Shao towards the antidepressant effect of Chaihu-Shu-Gan-San using metabonomics integrated with chemicalfingerprinting. Journal of Chromatography B. 2015, 1006 (2015):16–29 7.Cheng WH, Cao B, Shang H, Niu C, Zhang LM, Zhang ZH, Tian DL, Zhang S, Chen H*, Zou ZM* .Synthesis and evaluation of novel podophyllotoxin derivatives as potential antitumor agents. Eur J Med Chem. 2014,85C:498-507. 8.Ding G, Wang HL, Li L, Song B, Chen H, Zhang HW, Liu XZ, Zou ZM*. Trichodermone, a spiro-cytochalasan with a tetracyclic nucleus (7/5/6/5) skeleton from the plant endophytic fungus Trichoderma gamsii. J Nat Prod.2014,77(1):164-7 9.Su ZH, Jia HM, Zhang HW, Feng YF, An L, Zou ZM*. Hippocampus and serum metabolomic studies to explore the regulations of Chaihu-Shu-Gan-San on the metabolic network disturbances of rats exposed to chronic variable stress. Mol Biosyst.2014, 10:549-561 10.Liu YT, Peng JB, Jia HM, Zhang HW, Ding G, Zou ZM*. Urinary metabonomic evaluation of the therapeutic effect of traditional Chinese medicine Xin-Ke-Shu against atherosclerosis rabbits using UPLC-Q/TOF MS,Chemometrics and Intelligent Laboratory Systems. 2014, 136: 104-114 11.Chen L, Liu YT, Song B, Zhang HW, Ding G*, Liu XZ, Gu YC, Zou ZM*. Stereochemical determination of new cytochalasans from the plant endophytic fungus Trichoderma gamsii. Fitoterapia. 2014, 96C:115-122. 12.Liu YT, Jia HM, Chang X, Cheng WH, Zhao X, Ding G, Zhang HW, Cai DY, Zou ZM*. Metabolic pathways involved in Xin-Ke-Shu protecting against myocardial infarction in rats using ultra high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. J Pharm Biomed Anal. 2014,90:35-44 13.Liu YT, Peng JB, Jia HM, Cai DY, Zhang HW, Yu CY*,Zou ZM*, UPLC-Q/TOF MS standardized Chinese Formula Xin-Ke-Shu for the treatment of atherosclerosis in a rabbit model. Phytomedicine.2014, 21(11):1364-72 14.Liu YT, Jia HM, Chang X, Ding G, Zhang HW, Zou ZM*. The metabolic disturbances of isoproterenol induced myocardial infarction in rats based on a tissue targeted metabonomics. Mol Biosyst. 2013, 9(11):2823-2834. 15.Jia HM, Feng YF, Liu YT, Chang X, Chen L, Zhang HW, Ding G, Zou ZM*. Integration of 1H NMR and UPLC-Q-TOF/MS for a comprehensive urinary metabonomics study on a rat model of depression induced by chronic unpredictable mild stress, PLoS One. 2013,8(5):e63624 16.Tian XH, Li L, Hu YB, Zhang HW, Liu YT, Chen H, Ding G*, Zou ZM*. Dichrocephones A and B, Two Cytotoxic Sesquiterpenoids with the Unique [3.3.3] Propellane Nucleus Skeleton from Dichrocephala benthamii C. B. Clarke, RSC Adv. 2013, 3 (21):7880 – 7883 17.Ding G, Wang HL, Li L, Amanda Chen J, Chen L, Chen H, Zhang HW, Liu XZ, Zou ZM*. Trichoderones A and B: Two Pentacyclic Cytochalasans from the Plant Endophytic Fungus Trichoderma gamsii,Eur. J. Org. Chem. 2012, 2516–2519 18.Ding G, Chen L, Chen A, Tian X, Chen X, Zhang H, Chen H, Liu XZ, Zhang Y, Zou ZM*. Trichalasins C and D from the plant endophytic fungus Trichoderma gamsii. Fitoterapia. 2012,83(3):541-4 19.Ding G, Zhang F, Chen H, Guo L, Zou Z*, Che Y*. Pestaloquinols A and B, Isoprenylated Epoxyquinols from Pestalotiopsis sp, J Nat Prod. 2011, 74(2):286-91 20.Peng JB, Jia HM, Xu T, Liu YT, Zhang HW, Yu LL, Cai DY, Zou ZM*.A 1H NMR based metabonomics approach to progression of coronary atherosclerosis in a rabbit model, Process Biochemistry. 2011,46 :2240–2247

学术兼职

兼任国家科学技术奖、国家自然科学基金、科技部863、国际合作计划、中小企业创新基金等评审专家;中国药学会中药和天然药物专业委员会副主任委员兼秘书长,中国菌物学会菌物化学专业委员会副主任委员,世界中医药学会联合会中药化学专业委员会常务理事、中药分析专业委员会理事,北京药学会第十五届理事会理事、天然药物专业委员会副主任委员;天津中医药大学和河南中医药大学硕士生导师;Journal of Asian Natural Products Research、Pharmaceutical Crops、《中国天然药物》、《中国医药工业杂志》、《中国医药生物技术》和《亚太传统医药》等杂志编委。

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