个人简介
1991年北京农业大学生物学院大学本科毕业,1994年获北京农业大学硕士学位,1997-1998年日本大阪大学第25届联合国教科文组织(UNESCO)国际微生物学研究生班毕业,1999年获中国科学院植物研究所博士学位,1994-2000年中国科学院植物研究所实习研究员、助理研究员,2000-2002年美国密歇根理工大学博士后,2002-2007年美国北卡罗莱纳州立大学博士后,2007-2009年美国北卡罗莱纳州立大学研究助理教授,2009年至今中国医学科学院/北京协和医学院药用植物研究所研究员,2010-2013年中国医学科学院/北京协和医学院“协和学者”特聘教授。
研究领域
(1)药用植物次生代谢产物生物合成及调控的分子机制;(2)植物非编码RNA的种类和功能;(3)林木分子育种及植物纤维生物质的生物合成与生物技术;(4)植物胁迫响应的分子机理等。
近期论文
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1. Meizhen Wang, Shanfa Lu*. 2016. Validation of suitable reference genes for quantitative gene expression analysis in Panax ginseng. Frontiers in Plant Science, 6: 1259.
2. Qing Du, Caili Li, Dongqiao Li, Shanfa Lu*. 2015. Genome-wide analysis, molecular cloning and expression profiling reveal tissue-specifically expressed, feedback-regulated, stress-responsive and alternatively spliced novel genes involved in gibberellin metabolism in Salvia miltiorrhiza. BMC Genomics, 16, 1087.
3. Fenjuan Shao, Deyou Qiu, Shanfa Lu*. 2015. Comparative analysis of the Dicer-like gene family reveals loss of miR162 target site in SmDCL1 from Salvia miltiorrhiza. Scientific Reports, 5: 9891.
4. Caili Li, Dongqiao Li, Fenjuan Shao, Shanfa Lu*. 2015. Molecular cloning and expression analysis of WRKY transcription factor genes in Salvia miltiorrhiza. BMC Genomics. 16: 200.
5. Dongqiao Li, Fenjuan Shao, Shanfa Lu*. 2015. Identification and characterization of mRNA-like noncoding RNAs in Salvia miltiorrhiza. Planta, 241: 1131-1143.
6. Meizhen Wang, Bin Wu, Chao Chen, Shanfa Lu*. 2015. Identification of mRNA-like non-coding RNAs and validation of a mighty one named MAR in Panax ginseng. Journal of Integrative Plant Biology, 57: 256-270.
7. Caili Li, Shanfa Lu*. 2014. Molecular characterization of the SPL gene family in Populus trichocarpa. BMC Plant Biology, 14: 131.
8. Fenjuan Shao, Shanfa Lu*.2014. Identification, molecular cloning and expression analysis of five RNA-dependent RNA polymerase genes in Salvia miltiorrhiza. PLoS One, 9: e95117.
9. Caili Li, Shanfa Lu*. 2014. Genome-wide characterization and comparative analysis of R2R3-MYB transcription factors show the complexity of MYB-associated regulatory networks in Salvia miltiorrhiza. BMC Genomics, 15: 277.
10. Linsu Zhang, Bin Wu, Degang Zhao, Caili Li, Fenjuan Shao, Shanfa Lu*. 2014. Genome‐wide analysis and molecular dissection of the SPL gene family in Salvia miltiorrhiza. Journal of Integrative Plant Biology, 56: 38-50.
11. Shanfa Lu, Quanzi Li, Hairong Wei, Mao-Ju Chang, Sermsawat Tunlaya-Anukit, Hoon Kim, Jie Liu, Jingyuan Song, Ying-Hsuan Sun, Lichai Yuan, Ting-Feng Yeh, Ilona Peszlen, John Ralph, Ronald R. Sederoff, Vincent L. Chiang. 2013. Ptr-miR397a is a negative regulator of laccase genes affecting lignin content in Populus trichocarpa. Proc Natl Acad Sci USA, 110: 10848-10853.
12. Fenjuan Shao, Shanfa Lu*. 2013. Genome-wide identification, molecular cloning, expression profiling and posttranscriptional regulation analysis of the Argonaute gene family in Salvia miltiorrhiza, an emerging model medicinal plant. BMC Genomics, 14: 512.
13. Xuemei Hou, Fenjuan Shao, Yimian Ma, Shanfa Lu*. 2013. The phenylalanine ammonia-lyase gene family in Salvia miltiorrhiza: genome-wide characterization, molecular cloning and expression analysis. Molecular Biology Report, 40: 4301-4310.
14. Bin Wu, Ying Li, Haixia Yan, Yimian Ma, Hongmei Luo, Lichai Yuan, Shilin Chen, Shanfa Lu*. 2012. Comprehensive transcriptome analysis reveals novel genes involved in cardiac glycoside biosynthesis and mlncRNAs associated with secondary metabolism and stress response in Digitalis purpurea. BMC Genomics, 13: 15.
15. Bin Wu, Meizhen Wang, Yimian Ma, Lichai Yuan, Shanfa Lu*. 2012. High-throughput sequencing and characterization of the small RNA transcriptome reveal features of novel and conserved microRNAs in Panax ginseng. PLoS One, 7: e44385.
16. Yimian Ma, Lichai Yuan, Bin Wu, Xian'en Li, Shilin Chen, Shanfa Lu*. 2012. Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza. Journal of Experimental Botany, 63: 2809-2823.
17. Shanfa Lu*, Chenmin Yang, Vincent L. Chiang. 2011. Conservation and diversity of microRNA-associated copper-regulatory networks in Populus trichocarpa. Journal of Integrative Plant Biology, 53: 879-891.
18. Shanfa Lu*, Ying-Hsuan Sun, Vincent L. Chiang. 2009. Adenylation of plant miRNAs. Nucleic Acids Research, 37: 1878-1885.
19. Shanfa Lu*, Ying-Hsuan Sun, Vincent L. Chiang. 2008. Stress-responsive microRNAs in Populus trichocarpa. Plant Journal, 55: 131-151.
20. Shanfa Lu*, Laigeng Li, Xiaoping Yi, Chandrashekhar P. Joshi, Vincent L. Chiang. 2008. Differential expression of three eucalyptus secondary cell wall-related cellulose synthase genes in response to tension stress. Journal of Experimental Botany, 59: 681-695.
学术兼职
兼任BMC Genomics等八个国际杂志的编辑或编委,Plant Cell等三十多个国内外杂志的审稿人,国家重点研发计划和国家自然科学基金等十多个国际国内基金的项目评审专家,国家和教育部科学技术奖评审专家,中国医学科学院/北京协和医学院院校归国华侨联合会第二届委员会委员等。