个人简介
主要学习、工作、出国经历
198909 – 199307: 大学本科,安徽中医药大学
200109 – 200407: 硕士研究生,安徽中医药大学
200409 – 200706: 博士研究生,安徽医科大学
199307 – 至今:中国科学技术大学附属第一医院(安徽省立医院)工作
2018年4月:美国约翰霍普金斯大学医学院交流
研究领域
①医学分子生物学
②细胞免疫、分子机制与药物治疗。
目前正在承担的科研项目(仅限于主要负责人)
项目名称、来源、经费指标卡号 总经费(万元) 起止日期
糖尿病肾病系膜细胞源Exosome通过TGFβ1-PI3K/AKT通路影响足细胞的功能及小檗碱的作用(国家自然科学基金)
小檗碱通过AMPK改善糖尿病心肌病的机制研究(安徽省中医药科研课题) 财政拨款55万
医院配套55万
10 201801-202112
201608-201808
近期论文
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[1]Wang Ying-Ying, Tang Li-Qin *, Wei Wei *. Berberine attenuates podocytes injury caused by exosomes derived from high glucose-induced mesangial cells through TGFβ1-PI3K/AKT pathway. Eur J Pharmacol, 2018, 824:185-192
[2]Qiu Yuan-Ye, Tang Li-Qin *, Wei Wei *. Berberine exerts renoprotective effects by regulating the AGEs-RAGE signaling pathway in mesangial cells during diabetic nephropathy. Molecular and Cellular Endocrinology, 2017, 443:89-105
[3]Qiu Yuan-Ye , Tang Li-Qin *. Roles of the NLRP3 inflammasome in the pathogenesis of diabetic nephropathy. Pharmacological Research, 2016,114: 251-264
[4]Ni Wei-Jian, Tang Li-Qin *, Zhou Hong, Ding Hai-Hua, Qiu Yuan-Ye. Renoprotective effect of berberine via regulating the PGE 2-EP1-Gαq-Ca2+ signalling pathway in glomerular mesangial cells of diabetic rats. J Cell Mol Med.2016, 20(8):1491-1502
[5]Tang Li-Qin *, Ni Wei-Jian, Cai Ming, Ding Hai-Hua, Liu Sheng, Zhang Shan-Tang. Renoprotective effects of berberine and its potential effect on the expression of β-arrestins and intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in streptozocin-diabetic nephropathy rats. J Diabetes. 2016,8(5):693-700
[6]Ni Wei-Jian, Li-Qin Tang *, Wei Wei*. Research progress in signalling pathway in diabetic nephropathy. Diabetes Metab Res Rev. 2015, 31(3):221-33
[7]Ni Wei-Jian, Ding Hai-Hua, Tang Li-Qin *. Berberine as a promising anti-diabetic nephropathy drug: An analysis of its effects and mechanisms. Eur J Pharmacol, 2015, 760:103-112
[8]Ni Wei-Jian, Ding Hai-Hua, Zhou Hong, Qiu Yuan-Ye, Tang Li-Qin *. Renoprotective effects of berberine through regulation of the MMPs/TIMPs system in streptozocin-induced diabetic nephropathy in rats.Eur J Pharmacol. 2015, 764:448-456
[9]Tang Li-Qin *, Liu Sheng, Zhang Shan-Tang, Zhu Ling-Na, Wang Feng-Ling. Berberine regulates the expression of E-prostanoid receptors in diabetic rats with nephropathy. Molecular Biology Reports, 2014,41(5):3339-3347
[10]Tang Li-Qin *, Wang Feng-Ling, Zhu Ling-Na, Lv Fei, Liu Sheng, Zhang Shan-Tang. Berberine ameliorates renal injury by regulating G proteins-AC- cAMP signaling in diabetic rats with nephropathy, Molecular Biology Reports, 2013, 40(6):3913-3923
学术兼职
临床药学教研室主任、药剂科副主任、中国药理学会治疗药物监测研究专委会委员、安徽省药学会常务理事、安徽省药学会药物经济学专委会副主任委员