个人简介
教育背景:
1995年9月-1999年7月,沈阳药科大学,药物分析专业,学士。
1999年8月-2002年7月,军事医学科学院,药剂学专业,硕士。
2004年9月-2008年2月,香港中文大学,化学病理学专业,博士。
工作经历:
2008年3月-2008年8月,香港中文大学化学病理学系,研究助理。
2008年9月-2012年9月,中国医学科学院药物研究所药物制剂室,助理研究员。
2012年10月-至今,中国医学科学院药物研究所药物制剂室,副研究员。
研究领域
siRNA递送载体
基因递送系统
纳米制剂
肿瘤靶向制剂
缓控释制剂
近期论文
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1) Feifei Yang, Wei Huang (并列第一作者), Yunfei Li, Shan Liu, Mingji Jin, Yuli Wang, Lihua Jia, Zhonggao Gao. 2013. Anti-tumor effects in mice induced by Survivin-targeted siRNA delivered through polysaccharide nanoparticles. Biomaterials, 2013, 34(22): 5689-5699.
2) Holly Y. Chen, Wei Huang, Vincent H. K. Leung, Simon L. M. Fung, Suk Ling Ma, Hongling Jiang, Nelson L. S. Tang. Functional Interaction Between SNPs and Microsatellite in the Transcriptional Regulation of Insulin-Like Growth Factor 1. Human Mutation, 2013, 34(9):1289-1297.
3) Mingji Jin, Wei Chen, Wei Huang, Long Rong, Zhonggao Gao. Preparation of pegylated lumbrokinase and an evaluation of its thrombolytic activity both in vitro and in vivo. Acta Pharmaceutica Sinica B, 2013, 3(2):123-129.
4) Wei Huang, Ming Lv, Zhong-gao Gao, Ming-ji Jin, Yuan-ji Xu, Xiao-dan Yu, Zhe-hu Jin, Xue-zhe Yin. Preparation and characterization of polymeric nanoparticles for siRNA delivery to down-regulate the expressions of exogenous and endogenous target genes. Pharmazie, 2012, 67(8): 676-680.
5) Wei Huang, Ming Lv, Zhong Gao Gao. Synthesis of polyethylenimine grafted with copolymers of polyethylene glycol and polycaprolactone and its potential for siRNA delivery. Chin Chem Lett, 2011, 22(6):749-752.
6) Suk Ling Ma, Wei Huang, Nelson L.S. Tang, and Linda C.W. Lam. MxA Polymorphisms Are Associated with Risk and Age-at-Onset in Alzheimer Disease and Accelerated Cognitive Decline in Chinese Elders. Rejuvenation Research, 2012, 15(5):516-522.
7) Yunfei Li, Feifei Yang, Wei Chen, Jiaoyang Liu, Wei Huang, Mingji Jin, and Zhonggao Gao. A Novel Monomethoxy Polyethylene Glycol-Polylactic Acid Polymeric Micelles with Higher Loading Capacity for Docetaxel and Well-Reconstitution Characteristics and Its Anti-metastasis Study. Chem Pharm Bull,2012, 60(9):1146-1154.
8) Chan IH, Tang NL, Leung TF, Huang W, et al. Association of early growth response-1 gene polymorphisms with total IgE and atopy in asthmatic children. Pediatr Allergy Immunol. 2009, 20(2):142-150.
9) Chan IH, Tang NL, Leung TF, Huang W, et al. Study of gene-gene interactions for endophenotypic quantitative traits in Chinese asthmatic children. Allergy, 2008, 63(8):1031-1039.
10) Li H, et al. Polymorphisms in the C-type Lectin Genes Cluster in Chromosome 19 and Predisposition to SARS-Coronavirus Infection. J Med Genet, 2008, 45(11):752-758., Tang NL, Chan PK, Wang CY, Hui DS, Luk C, Kwok R,Huang W
11) Wei Huang, Leung-sang Tang, Yu-li Wang, Zhong-gao Gao, Ying-man Sung, Hiu-shuen Chan, Loi-mo Fung, Hoi-kei Kwok. Effect of SNP -705T>C and -603T>A in P1 promoter region of human IGF-I gene on promoter activity. 解放军医学杂志, 2012, 37(1):34-39.
12) 黄伟, 吕明, 高钟镐, 金明姬,杨飞飞,王玉丽. 非病毒性基因治疗递送载体(mPEG5k-PCL1.2k)1.4-g-PEI10k的构建及性能研究. 解放军医学杂志, 2011, 36(5):437-441.
13) 黄伟, 吕明, 李保卫,王玉丽,邵荣光,高钟镐. 大鼠脑胶质瘤荧光素酶动物模型建模细胞株C6-Luc的构建. 解放军医学杂志, 2011, 36(1):35-38.