个人简介
Paul Dyson joined the Institute of Chemical Sciences and Engineering at the EPFL in 2002 where he heads the Laboratory of Organometallic and Medicinal Chemistry. In 2021 he was appointed Dean of the Faculty of Basic Sciences. Between 2008 and 2016 he chaired the Institute.
He has won several prizes including the Werner Prize of the Swiss Chemical Society in 2004, the Award for Outstanding Achievements in Bioorganometallic Chemistry in 2010, the Centennial Luigi Sacconi Medal of the Italian Chemical Society in 2011, the Bioinorganic Chemistry Award of the Royal Society of Chemistry in 2015, the European Sustainable Chemistry Award of the European Chemical Society in 2018 and the Green Chemistry Award from the Royal Society of Chemistry in 2020. He has an H-index >115 (google scholar). He was elected a Fellow of the Royal Society of Chemistry in 2010, a Fellow of the European Academy of Science in 2019 and a life-long fellow of the American Association for the Advancement of Science in 2020. Over the years he has held visiting professorships at the University of Bourgogne, University of Pierre et Marie Curie, University of Vienna, University of Rome Tor Vergara, Chimie Paristech, Shangai Jiao Tong University and Lanzhou Institute of Chemical Physics.
Between 2016-2021 he was a Member of the Council of the Division of Mathematics, Natural and Engineering Sciences at the Swiss National Science Foundation and also served on the International Committee.
Paul Dyson rejoignit l’EPFL en 2002 à la tête du Laboratoire de chimie organométallique et médicinale de l’Institut des sciences et ingénierie chimiques, dont il en assuma ensuite la direction entre 2008 et 2016.
Le prof. Dyson a été récompensé par de nombreux prix dont le Prix Werner de la Société Suisse de Chimie en 2004, le Prix pour les réalisations exceptionnelles en chimie bio organométallique en 2010, la Médaille du Centenaire de la naissance de Luigi Sacconi (2011) de la Société Italienne de Chimie, le Prix de Chimie bio-inorganique de la Royal Society of Chemistry en 2015, le Prix européen pour une chimie durable de la Société Européenne de Chimie en 2018 et le Prix pour la chimie verte de la Royal Society of Chemistry en 2020.
Le prof. Dyson est également mentionné dans la liste établie par Clarivate des chercheurs les plus cités (Clarivate Highly Cited Researcher), avec un H-index >115 (google scholar).
Paul Dyson a été élu membre de la Royal Société de Chimie en 2010, membre de l’Académie Européenne des Sciences en 2019 et membre à vie de l’Association Américaine pour l’Avancement de la Science en 2020. Au cours des dernières années il s’est vu décerner le titre de Professeurs Hôte par l’Université de Bourgogne, l’Université de Pierre et Marie Curie, l’Université de Vienne, l’Université de Rome Tor Vergara, l’Ecole Nationale Supérieure de chimie de Paris (Chimie ParisTech), l’Université de Shangai Jiao Tong et par le Lanzhou Institute of Chemical Physics.
De 2016 à 2021 il était membre du conseil de la recherche de la division de mathématique, sciences naturelles et de l’ingénieur du Fonds National Suisse. En 2021, il a été nommé doyen de la Faculté des Sciences de Base.
研究领域
The research in Paul Dyson’s lab centres on organometallic chemistry at the interface with medicine, catalysis and material science. The main topics studied in his lab include:
Synthesis of functional organometallic compounds.
Design of new organometallic drugs and studying their mechanism of action.
Design of new homogeneous and nanoparticle catalysts.
Mechanistic studies of catalysed reactions.
Ionic liquids – design, properties, reactivity and catalysis.
Les recherches au sein du laboratoire du Prof. Paul Dyson portent sur la chimie organométallique en lien avec la médecine, la catalyse et la science des matériaux. Les principaux thèmes de recherche de son laboratoire sont :
La synthèse de composés organométalliques fonctionnels.
La conception de nouveaux médicaments organométalliques et étude de leur mécanisme d’action.
La conception de nouveaux catalyseurs (homogène et nanoparticules).
L’étude mécanistique de réactions catalysées.
Les liquides ioniques – développement, propriétés, réactivité et catalyse.
近期论文
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Tandem catalysis enables chlorine-containing waste as chlorination reagents M. Liu; X. Wu; P. J. Dyson Nature Chemistry. 2024-02-23. DOI : 10.1038/s41557-024-01462-8
Heteroatom Engineering of a Dibenzo[g,p]Chrysene-Based Hole Transporting Material Provides High-Performance Perovskite Solar Cells X. Zhang; S. Zhang; X. Liao; B. Ding; G. Rahim et al. Advanced Functional Materials. 2024-02-21. DOI : 10.1002/adfm.202314086
Ginkgo Leaf-Derived Carbon Supports for the Immobilization of Iron/Iron Phosphide Nanospheres for Electrocatalytic Hydrogen Evolution Q. Wang; Z. Fei; D. Shen; C. Cheng; P. J. Dyson Small. 2024-01-04. DOI : 10.1002/smll.202309830
Autocatalysis and CO2: Carbon Capture and Utilization (CCU) Meets Natural Processes G. Gastelu; P. Saha; P. J. Dyson; M. Hulla; J. G. Uranga Chemcatchem. 2023-11-06. DOI : 10.1002/cctc.202300905
Fine-tuning the cytotoxicity of ruthenium(ii) arene compounds to enhance selectivity against breast cancers S. A. P. Pereira; J. Romano-deGea; A. I. Barbosa; S. A. C. A. Lima; P. J. J. Dyson et al. Dalton Transactions. 2023-07-28. Vol. 52 , num. 33, p. 11679-11690.. DOI : 10.1039/d3dt02037a
The predictive capacity of in vitro preclinical models to evaluate drugs for the treatment of retinoblastoma I. L. Sinenko; R. C. Turnell-Ritson; F. L. Munier; P. J. Dyson Experimental Eye Research. 2023-03-23. Vol. 230 , p. 109447.. DOI : 10.1016/j.exer.2023.109447
Direct conversion of lignin to functionalized diaryl ethers via oxidative cross-coupling M. Liu; P. J. Dyson Nature Communications. 2023. Vol. 14 , num. 2830.. DOI : 10.1038/s41467-023-38534-1
Competitive binding studies of the nucleosomal histone targeting drug, [Ru (eta(6)-p-cymene)Cl-2(pta)] (RAPTA-C), with oligonucleotide-peptide mixtures. F. Mansouri; D. Ortiz; P. J. Dyson Journal Of Inorganic Biochemistry. 2023-01-01. Vol. 238 , p. 112043.. DOI : 10.1016/j.jinorgbio.2022.112043
Automated approach for the evaluation of glutathione-S-transferase P1-1 inhibition by organometallic anticancer compounds S. A. P. Pereira; A. C. L. Baptista; L. Biancalana; F. Marchetti; P. J. Dyson et al. Journal Of Enzyme Inhibition And Medicinal Chemistry. 2022-12-31. Vol. 37 , num. 1, p. 1527-1536.. DOI : 10.1080/14756366.2022.2073443
Design of Frustrated Lewis Pair Catalysts for Direct Hydrogenation of CO2 S. Das; R. C. Turnell-Ritson; P. J. Dyson; C. Corminboeuf Angewandte Chemie-International Edition. 2022-10-17. Vol. 61 , num. 46, p. e202208987.. DOI : 10.1002/anie.202208987
Simultaneous Generation of Methyl Esters and CO in Lignin Transformation M. Liu; B. Han; P. J. Dyson Angewandte Chemie-International Edition. 2022-09-01 p. e202209093.. DOI : 10.1002/anie.202209093
Assessment of metal-based dihydrofolate reductase inhibitors on a novel mesofluidic platform S. A. P. Pereira; L. Biancalana; F. Marchetti; P. J. Dyson; M. L. M. F. S. Saraiva Sensors And Actuators B-Chemical. 2022-09-01. Vol. 366 , p. 131978.. DOI : 10.1016/j.snb.2022.131978
Tandem Pauson-Khand Reaction Using Carbon Dioxide as the C1-Source S. Shyshkanov; D. V. Vasilyev; K. A. Abhyankar; K. C. Stylianou; P. J. Dyson European Journal Of Inorganic Chemistry. 2022-05-31. Vol. 2022 , num. 18, p. e202200037.. DOI : 10.1002/ejic.202200037
Chlorination of arenes via the degradation of toxic chlorophenols M. Liu; X. Yang; P. J. Dyson Proceedings of the National Academy of Sciences. 2022-05-19. Vol. 119 , num. 21, p. 1-6, e2122425119.. DOI : 10.1073/pnas.2122425119
Future Swiss Energy Economy: The Challenge of Storing Renewable Energy A. Zuettel; N. Gallandat; P. J. Dyson; L. Schlapbach; P. W. Gilgen et al. Frontiers In Energy Research. 2022-02-01. Vol. 9 , p. 785908.. DOI : 10.3389/fenrg.2021.785908
Society and Chemistry They Are a-Changin’N. Cramer; P. J. Dyson Chimia. 2021-10-01. Vol. 75 , num. 10, p. 895-896.. DOI : 10.2533/chimia.2021.895
Efficient Solid-State Electrolytes Based on Aryl-Modified Imidazolium Ionic Crystals for Quantum Dot-Sensitized Solar Cells G. Zhao; Y. Wang; J-H. Zeng; Z. Fei; P. J. Dyson Acs Applied Energy Materials. 2021-09-28. Vol. 4 , num. 10, p. 10739-10747.. DOI : 10.1021/acsaem.1c01720
Boosting hydrogen production via urea electrolysis on an amorphous nickel phosphide/graphene hybrid structure Y. Tong; L. Chen; P. J. Dyson; Z. Fei Journal Of Materials Science. 2021-08-05. Vol. 56 , p. 17709–17720.. DOI : 10.1007/s10853-021-06391-2
Anticancer activity of RAPTA-EA1 in triple-negative BRCA1 proficient breast cancer cells: single and combined treatment with the PARP inhibitor olaparib K. Hongthong; T. Nhukeaw; P. Temboot; P. J. Dyson; A. Ratanaphan Heliyon. 2021-08-01. Vol. 7 , num. 8, p. e07749.. DOI : 10.1016/j.heliyon.2021.e07749
Recent advances in graphite carbon nitride-based nanocomposites: structure, antibacterial properties and synergies K. Yan; C. Mu; L. Meng; Z. Fei; P. J. Dyson . Nanoscale Advances. 2021-05-28. Vol. 3 , num. 13, p. 3708-3729.. DOI : 10.1039/d1na00257k
Automatic evaluation of cyclooxygenase 2 inhibition induced by metal-based anticancer compounds S. A. P. Pereira; F. D. Bobbink; P. J. Dyson; M. L. M. F. S. Saraiva Journal Of Inorganic Biochemistry. 2021-05-01. Vol. 218 , p. 111399.. DOI : 10.1016/j.jinorgbio.2021.111399
The Role of Organic Promoters in the Electroreduction of Carbon Dioxide D. V. Vasilyev; P. J. Dyson Acs Catalysis. 2021-02-05. Vol. 11 , num. 3, p. 1392-1405.. DOI : 10.1021/acscatal.0c04283
Aom(2)S: A new web-based application for DNA/RNA tandem mass spectrometry data interpretation D. Ortiz; N. Gasilova; F. Sepulveda; L. Patiny; P. J. Dyson et al. Rapid Communications In Mass Spectrometry. 2020-12-15. Vol. 34 , num. 23, p. e8927.. DOI : 10.1002/rcm.8927
Liquid Nitrogen-Mediated Thermal Shock for Instantaneous Detachment of Multi-walled Carbon Nanotube Films from Substrates and Their Application in Supercapacitors Z. Huang; H. Jia; Z. Fei; P. J. Dyson Acs Applied Nano Materials. 2020-11-25. Vol. 3 , num. 11, p. 11581-11586.. DOI : 10.1021/acsanm.0c02703
Masking specific effects of ionic liquid constituents at the solid-liquid interface by surface functionalization B. Katana; D. Takacs; F. D. Bobbink; P. J. Dyson; N. B. Alsharif et al. Physical Chemistry Chemical Physics. 2020-11-14. Vol. 22 , num. 42, p. 24764-24770.. DOI : 10.1039/d0cp02805c
Utility of Core-Shell Nanomaterials in the Catalytic Transformations of Renewable Substrates X. Cui; A. P. van Muyden; P. J. Dyson Chemistry-A European Journal. 2020-10-27. Vol. 27 , num. 1, p. 12-19.. DOI : 10.1002/chem.202002597
Facile synthesis of heterobimetallic [Fe II (?-diphosphine)Ru II ] and homobimetallic [Fe II (?-diphosphine)Fe II ] complexes and their in vitro cytotoxic activity on cisplatin-resistant cancer cells D. BenYosef; D. Romano; M. Hadiji; P. J. Dyson; B. Blom Inorganica Chimica Acta. 2020-09-24. Vol. 510 , p. 119731.. DOI : 10.1016/j.ica.2020.119731
Depletion Effect-mediated Association of Carbon Nanotube-Polymer Composites and Their Application as Inexpensive Electrode Support Materials Z. Huang; P. J. Dyson . Nano Letters. 2020-07-08. Vol. 20 , num. 7, p. 5353-5358.. DOI : 10.1021/acs.nanolett.0c01718
Miniaturized technologies for high-throughput drug screening enzymatic assays and diagnostics – A review S. A. P. Pereira; P. J. Dyson; M. L. M. F. S. Saraiva Trac-Trends In Analytical Chemistry. 2020-05-01. Vol. 126 , p. 115862.. DOI : 10.1016/j.trac.2020.115862
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