个人简介
教育背景：
1987/09-1991/07，成都科技大学，应用化学系，分析化学专业，学士
1995/09-1998/07，山西大学，化学系，分析化学专业，硕士
2001/09-2004/07，中国医学科学院药物研究所，药物分析专业，博士
工作经历：
1991/7-1995/9，山西医学院，卫生系，助教
1998/7-2001/8，山西医科大学，药学系，讲师
2004/08-至今，中国医学科学院&北京协和医学院药物研究所，国家药物及代谢产物分析研究中心，助理研究员、副研究员
研究领域
天然药物活性物质多组分复杂体系的质谱分析方法研究；
重大疾病的代谢组学分析方法研究。
近期论文
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1) Zhonghua Wang, Baoxin Zhao, Xuhui Liu, Yajie Zheng, Junxia Wang, Ruiping Zhang* and Zeper Abliz. A rapid and sensitive liquid chromatography-tandem mass spectrometry method for the quantitation of S-phenylmercapturic acid in human urine. Anal Methods, 2013, 5: 6081-6085.
2) Jiang Huang, Jianghao Sun, Yanhua Chen, Yongmei Song, Lijia Dong, Qinmin Zhan, Ruiping Zhang*, Zeper Abliz*. Analysis of multiplex endogenous estrogen metabolites in human urine using ultra-fast liquid chromatography-tandem mass spectrometry: A case study for breast cancer. Anal Chim Acta, 2012, 711: 60–68.
3) Yaping Tian, Jiuming He, Ruiping Zhang*, Haining Lv, Shuanggang Ma, Yanhua Chen, Shishan Yu, Xiaoguang Chen, Yan Wu, Wenyi He, Zeper Abliz*. Integrated rapid resolution liquid chromatography-tandem mass spectrometric approach for screening and identification of metabolites of the potential anticancer agent 3,6,7-trimethoxyphenanthroindolizidine in rat urine. Anal Chim Acta, 2012, 731: 60-67.
4) Na Guo, Ruiping Zhang, Fei Song, Jiuming He, Bin Xia, Zeper Abliz*. Characterization of acid-induced protein conformational changes and noncovalent complexes in solution by using coldspray ionization mass spectrometry. J Am Soc Mass Spectrom, 2009, 20: 845-851.
5) Ying Liu, Jiuming He, Ruiping Zhang, Jiangong Shi, Zeper Abliz*. Study of the characteristic fragmentation behavior of hydroquinone glycosides by electrospray ionization tandem mass spectrometry with optimization of collision energy. J Mass Spectrom, 2009, 44(8): 1182-1187.
6) Ping Geng, Jianghao Sun, Ruiping Zhang, Jiuming He, Zeper Abliz*. An investigation of the fragmentation differences of isomeric flavonol-O-glycosides under different collision-induced dissociation based mass spectrometry. Rapid Commun Mass Spectrom, 2009, 23(10): 1519-1524.
7) Yanhua Chen, Ruiping Zhang, Yongmei Song, Jiuming He, Jianghao Sun, Jinfa Bai, Zhuoling An, Lijia Dong, Qimin Zhan and Zeper Abliz*. RRLC-MS/MS-based metabonomics combined with in-depth analysis of metabolic correlation network: finding potential biomarkers for breast cancer. Analyst, 2009, 134(10): 2003-2011.
8) Jian Liu, Ruiping Zhang, Jiuming He, Ying Liu, Jiangong Shi, Zeper Abliz*. The characteristic fragmentation and rearrangement reaction of cationized glucopyranosyloxybenzyl tartrates by tandem mass spectrometry. J Mass Spectrom, 2010, 45(7): 824-828.
9) Zhuoling An, Yanhua Chen, Ruiping Zhang, Yongmei Song, Jianghao Sun, Jiuming He, Jinfa Bai, Lijia Dong, Qimin Zhan and Zeper Abliz*. Integrated Ionization Approach for RRLC-MS/MS-based Metabonomics: Finding Potential Biomarkers for Lung Cancer. J Proteome Res, 2010, 9(8): 4071-4081.
10) Jing Xu, Yanhua Chen, Ruiping Zhang, Yongmei Song, Jianzhong Cao, Nan Bi, Jingbo Wang, Jiuming He, Jinfa Bai, Lijia Dong, Lvhua Wang, Qimin Zhan and Zeper Abliz*. Global and Targeted Metabolomics of Esophageal Squamous Cell Carcinoma Discovers Potential Diagnostic and Therapeutic Biomarkers. Mol Cell Proteomics, 2013, 12: 1306-1318.
11) Yanhua Chen, Jing Xu, Ruiping Zhang, Guoqing Shen, Yongmei Song, Jianghao Sun, Jiuming He, Qimin Zhan and Zeper Abliz*. Assessment of Data Pre-processing Methods for LC-MS/MS-based Metabolomics of Uterine Cervix Cancer. Analyst, 2013, 138, 2669-2677.
12) 习聪, 陈艳华, 杨维, 张瑞萍*, 贺玖明, 张化冰, 肖新华, 再帕尔•阿不力孜. 脂质组学血清样品处理方法及其快速高分辨液相色谱-质谱分析. 分析化学, 2013, 41(9): 1308-1314.
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