个人简介
教育背景
1995.9-1999.7 山东医科大学药学院药学专业学士
1999.9-2002.7 山东大学药学院药理专业硕士
2002.9-2005.7 中国医学科学院/北京协和医学院药物研究所 博士
工作经历
2005.9-2010.8 中国医学科学院/北京协和医学院药物研究所 助理研究员
2010.9~ 中国医学科学院/北京协和医学院药物研究所 副研究员
研究领域
主要研究方向为肝脏生化药理学，包括各种肝病相关防治药物的活性筛选、评价、作用机理研究及肝病慢性化机制研究，也开展部分肿瘤耐药相关工作。
近期论文
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1. Sun H, Yu LH, Wei HL, Liu GT. A novel anti-hepatitis drug, bicyclol,prevents liver carcinogenesis in diethylnitrosamine-initiated and phenobarbital-phenobarbital-promoted mice tumor model. J Biomed Biotechnol. 2012. 2012,584728.
2. Wang YJ, Chen XG, Xiao ZY, Liu GT, Sun H*. Induction of cell cycle arrest by GL331 via triggering an ATM-dependent DNA damage response in HepG2 cells. J Asian Nat Prod Res. 2012, 14(7):657-64.
3. Wei N, Liu GT, Chen XG, Liu Q, Wang FP, Sun H*. H1, a derivative of Tetrandrine, exerts anti-MDR activity by initiating intrinsic apoptosis pathway and inhibiting the activation of Erk1/2and Akt1/2. Biochem Pharmacol. 2011, 82(11):1593-603.
4. Sun H, Liu GT. Chemopreventive effect of bicyclol on malignant transformation of WB-F344 rat liver epithelial cells and its effect on related signal transduction in vitro.Cancer Lett. 2006, 236(2): 239-49.
5. Sun H. Liu GT. Inhibitory effect of anti-hepatitis drug bicyclol on invasion of human hepatocellular carcinoma MHCC97-H cells with high metastasis potential and its relative mechanisms. J Asian Nat Prod Res. 2009, 11(6): 576-83.
6. Liu XD, Sun H, Liu GT, 5-bromotetrandrine enhances the sensitivity of doxorubicin-induced apoptosis in intrinsic resistant human hepatic cancer Bel7402 cells. Cancer lett. 2010, 292(1): 24-31.
7. Wei N, Sun H, Wang FP, Liu GT. H1, a novel derivative of tetrandrine reverse P-glycoprotein-mediated multidrug resistance by inhibiting transport function and expression of P-glycoprotein. Cancer Chemother Pharmacol. 2011, 67(5):1017-25.
8. Jin J, Sun H, Wei HL, Liu GT. The anti-hepatitis drug DDB chemosensitizes multidrug resistant cancer cells in vitro and in vivo by inhibiting P-gp and enhancing apoptosis. Invest New Drugs. 2007, 25(2):95-105.
9. He P, Sun H, Jian XX, Chen QH, Chen DL, Liu GT, Wang FP. Partial synthesis and biological evaluation of bisbenzylisoquinoline alkaloids derivatives: potential modulators of multidrug resistance in cancer. J Asian Nat Prod Res.2012, 14(6): 564-76.
10. Tian Y, Xu W, Zhu C, Lin S, Li Y, Xiong L, Wang S, Yang Y, Guo Y, Sun H, Wang X, Shi J. Lathyrane diterpenoids from the roots of Euphorbia micractina and their biological activities. J Nat Prod. 2011, 74(5):1221-9.
11. Qiao LR, Yang L, Zou JH, Li L, Sun H, Si YK, Zhang D, Chen X, Dai J. Neolignans and Sesquiterpenes from cell culture of stellera chamaejasme. Planta Med. 2012, 78(7):711-9.
12. Hao ZY, Liang D, Luo H, Liu YF, Ni G, Zhang QJ, Li L, Si YK, Sun H, Chen RY, Yu DQ. Bioactive Sesquiterpenoids from the Rhizomes of Acorus calamus. J Nat Prod. 2012, 75(6):1083-9.
13. Hao ZY, Liang D, Luo H, Liu YF, Ni G, Zhang QJ, Li L, Si YK, Sun H, Chen RY, Yu DQ. Bioactive Sesquiterpenoids from the Rhizomes of Acorus calamus. J Nat Prod. 2012, 75(6):1083-9.
14.王娅杰,陈晓光,肖志艳,刘耕陶,孙华*. 拓扑异构酶Ⅱ抑制剂GL331对HepG2细胞体外生长的抑制作用. 中国新药杂志,2012,21(9),983-8.
15.孙华,刘耕陶. 五味子果仁醇提取物含药血清逆转肿瘤多药耐药及抑制耐药糖蛋白（P-gp）的作用. 中国新药杂志. 2009, 18(12),1130-5.
16.孙华,魏怀玲,刘耕陶. 治肝炎药物联苯双酯对肝癌的化学预防作用。解放军医学杂志. 2010, 35(12): 1438-41.
17.余凌虹，魏怀玲，鲍秀琦，张丹*，孙华*. 番荔枝酰胺衍生物FLZ对LPS联合MPTP诱发小鼠慢性帕金森病的治疗作用. 药学学报, 2013,48(10):1557-1562.
18.孙华，余凌虹，魏怀玲，张丹*.双环醇拮抗DDT引起的细胞间隙连接通讯功能抑制研究. 中国药物警戒, 2013,10(7):385-389.
19.余凌虹，魏怀玲，鲍秀琦，陈晓光，张丹，孙华*. 双环醇对奥沙利铂联合5-氟尿嘧啶方案引起肝损伤保护作用的实验研究. 中国药物警戒, 2013,10(2): 68-71.
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