朱平 - 中国医学科学院药物研究所 -

个人简介

1988年中国协和医科大学微生物药物学专业研究生毕业，之后，在药物所工作至今。1991年-1993年由欧共体资助在英国诺丁汉大学进修丝状真菌分子生物学。2004年4月-11月，作为访问教授在美国夏维夷大学从事海绵相关微生物研究。

研究领域

微生物工程与天然药物合成生物学。目前主要开展：1.天然药物合成生物技术研究，包括天然药物合成生物学、药用催化酶或生物活性蛋白的基因克隆与异源表达和利用；2. 海绵等动植物内生菌及药用真菌活性代谢产物研究。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Liu WC, Gong T, Zhu P*. Advances in exploring alternative Taxol sources. RSC Advances. 2016, 6,48800-48809. 2. Liu WC, Gong T, Wang QH, Liang X, Chen JJ, Zhu P.* Scaling-up fermentation of Pichia pastoris to demonstration-scale using new methanol-feeding strategy and increased air pressure instead of pure oxygen supplement. Scientific Reports. 2016, 6,18439. 3. Zhen X, Gong T(co-first author), Liu F, Zhang PC, Zhou WQ, Li Y, Zhu P*. A new analogue of echinomycin and a new cyclic dipeptide from a marine-derived Streptomyces sp. LS298. Marine Drugs, 2015, 13(11), 6947-6961. 4. Gong T, Zhen X, Li BJ, Yang JL, Zhu P*. Two new monoterpenoid α-pyrones from a fungus Nectria sp. HLS206 associated with the marine sponge Gelliodes carnosa. J Asian Nat Prod Res. 2015, 17(6), 633-637. 5. Liu WC, Zhu P*. Pilot studies on scale‑up biocatalysis of 7‑β‑xylosyl‑10‑deacetyltaxol and its analogues by an engineered yeast. J Ind Microbiol Biotechnol. 2015, 42, 867-876. 6. Wu C, Guo Y, Su Y, Zhang X, Luan H, Zhang X, Zhu H, He H, Wang X, Sun G, Sun X, Guo P*, Zhu P*. Cordycepin activates AMP-activated protein kinase (AMPK) via interaction with the γ1 subunit. J Cell Mol Med. 2014, 18(2), 293-304. 7.Gong T, Zheng L, Zhen X, He HX, Zhu HX, Zhu P*. Microbial transformation of oleanolic acid by Trichothecium roseum. J Asian Nat Prod Res. 2014, 16(4), 383-386. 8. Chen HL, Zhao RY, Chen TJ, Yu WB, Wang F, Cheng KD, Zhu P*. Cloning and characterization of the glycoside hydrolases that remove xylosyl group from 7-b-xylosyl-10-deacetyltaxol and its analogues. Mol Cell Proteomics. 2013,12(8), 2236-2248. (Cover Image and the Highlight from this Issue) 9. Yu WB, Liang X, Zhu P*. High-cell-density fermentation and pilot-scale biocatalytic studies of an engineered yeast expressing the heterologous glycoside hydrolase of 7-b-xylosyltaxanes. J Ind Microbiol Biotechnol. 2013, 40,133-140. 10. Zhu H, Hua XX, Gong T, Pang J, Hou Q, Zhu P*. Hypocreaterpenes A and B, cadinane-type sesquiterpenes from a marine-derived fungus, Hypocreales sp. Phytochemistry Letters. 2013, 6, 392-396. 11. Shen J, Zheng H, Zhi X, Shi Y, Huang Y, Wang W, Chen Y, Kong J*, Zhu P*. Improvement of amorpha-4,11-diene production by a yeast-conform variant of Vitreoscilla hemoglobin. Z Naturforsch. 2012, 67c,195-207. 12. Li CQ, Liu WC, Zhu P*, Yang JL, Cheng KD. Phylogenetic diversity of bacteria associated with the marine sponge Gelliodes carnosa collected from the Hainan island coastal waters of the South China Sea. Microbial Ecology. 2011,62, 800-812. 13. Liu WC, Li, CQ, Zhu P*. Yang JL, Cheng KD. Phylogenetic diversity of culturable fungi associated with two marine sponges: Haliclona simulans and Gelliodes carnosa, collected from the Hainan Island coastal waters of the South China Sea. Fungal Diversity. 2010, 42, 1-15. 14. Zhao RY, Xiao W, Cheng HL, Zhu P*, Cheng KD. Cloning and Characterization of Squalene Synthase Gene from Fusarium fujikuroi (Saw.) Wr. J Ind Microbiol Biotechnol. 2010, 37,1171-1182. 15. Yang JL, Zhu P*, Cheng GF, Cheng KD, He HX, Zhu HX. Expression, purification and characterization of an analgesic peptide from Buthus martensii Karsch in Pichia pastoris. World J Microbiol Biotechnol. 2009, 25, 2053-2056. 16. Hu CX, Huang H, Zhang L, Huang Y, Shen ZF, Cheng KD, Du GH, Zhu P*. A new screening method based on yeast-expressed human dipeptidyl peptidase IV and discovery of novel inhibitors. Biotechnol Lett. 2009, 31, 979–984. 17. Kong JQ*, Wang W*, Wang LN, Zheng XD, Cheng KD, Zhu P*. The Improvement of amorpha-4,11-diene production by a yeast-conform variant. J Appl Microbiol. 2009, 106, 941-951. 18. Zhu P, Li Q, Wang G. Unique microbial signatures of the alien Hawaiian marine sponge Suberites zeteki. Microb Ecol. 2008, 55, 406–414. 19. Yuan W, Zhang LP, Cheng KD , Zhu P*， Wang Q, He HX, Zhu HX. Microbial O-demethylation, hydroxylation, sulfation and ribosylation of a xanthone derivative from Halenia elliptica. J Nat Prod. 2006, 69, 811-814.