个人简介
教育背景：
2001/02 – 2003/05，南卡罗莱那医科大学（MUSC，USA），博士后
1997/9-2000/6, 中国医学科学院药物研究所，博士
1989/09 - 1991/06，山东大学医学院，硕士
1982/09-1987/06 滨州医学院，学士
工作经历：
2007/03 - 至今，中国医学科学院药物研究所，研究员。
2003/5-2007/3，MUSC，USA，助理教授
1987/9-1997/6 潍坊医学院，天然药物与药理学研究室，副教授
研究领域
1. 抗炎免疫药理学
2. 哮喘、COPD气道炎症调控靶标及其创新药物的发现研究
3. 缺血缺氧性氧化应激炎症防治先导化合物的筛选及其创新药物发现
4. 基于免疫平衡的药物过敏性机制研究
近期论文
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1. Mingbao Lin, Wei Sun, Wan Gong, Zhiyu Zhou, Yasi Ding, Qi Hou*. Methylophiopogonanone A Protects against Cerebral Ischemia/Reperfusion Injury and Attenuates Blood-Brain Barrier Disruption In Vitro [J]. PLoS ONE, 2015; 10(4): e0124558. doi:10.1371/journal.pone.0124558.
2. Mingbao Lin, Wei Sun, Wan Gong, Yasi Ding, Yuanyan Zhuang, Qi Hou*. Ginsenoside Rg1 protects against transient focal cerebral ischemic injury and suppresses its systemic metabolic changes in cerabral injury rats [J]. Acta Pharmaceutica Sinica B, 2015; 5(3): 277–284.
3. Weibin Tang#, Jianlin Xie#, Song Xu, Haining Lv, Mingbao Lin, Shaopeng Yuan, Jinye Bai, Qi Hou*, and Shishan Yu*. Novel Nitric Oxide-Releasing Derivatives of Brusatol as Anti-Inflammatory Agents: Design, Synthesis, Biological Evaluation, andNitric Oxide Release Studies [J]. Journal of Medicinal Chemistry, 2014(57): 7600-7612.
4. Ling-ling XUAN, Ji SHI, Chun-suo YAO, Jin-ye BAI, Feng QU, Jin-lan ZHANG, Qi HOU*. Vam3, a resveratrol dimer, inhibits cigarette smoke-induced cell apoptosis in lungs by improving mitochondrial function [J]. Acta Pharmacologica Sinica, 35(2014): 779-791.
5. Shaopeng Yuan, Shuhua Cao, Rentao Jiang, Renping Liu, Jinye Bai, Qi Hou*. FLLL31, a derivative of curcumin, attenuates airway inflammation in a multi-allergen challenged mouse model[J]. International Immunopharmacology, 21(2014): 128-136.
6. Su Lu, Xiaotian Qin, Shaopeng Yuan, Yawei Li, Liming Wang, Yusheng Jin, Gang Zeng, Lawrence Yen, Jenny Hu, Tracie Dang, Sophie Song, Qi Hou*, Jianyu Rao*. Effect of Tianshengyuan-1 (TSY-1) on telomerase activity and hematopoietic recovery - in vitro, ex vivo, and in vivo studies [J]. Inflammation, 2013(36): 845-854.
7. Liu Renping, Bai Jinye, Xu Guoshun, Xuan Lingling, Zhang Tianqi, Meng Aiming, Hou Qi*. Multi-Allergen Challenge Stimulates Steriod-Resistant Airway Inflammation via NF-κB-Mediated IL-8 Expression[J]. Inflammation, 2013, 36(4): 845-854.
8. Shi J, in N, Xuan LL, Yao CS, Meng AM, and Hou Q*. Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy. Acta Pharmacol Sin. 2012 Jul; 33(7): 888-96.
9. Hou Q, Jin J, Jacqueline M. Kraveka, Alicja B, Lina M. Obeid, Yusuf A. Hannun, and Yi-Te Hsu. Mitochondrially targeted ceramide preferentially promotes autophagy, retards cell growth and induces apoptosis. J Lipid Res. 2011, 52:278 - 288.
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