研究领域
主要研究方向包括黏膜免疫与疫苗、干细胞技术与组织再生修复。
近期论文
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1. Zhu Q, Talton J, Zhang G, Cunningham T, Wang Z, Waters RC, Kirk J, Eppler B, Klinman DM, Sui Y, Gagnon S, Belyakov IM, Mumper RJ, Berzofsky JA. Large intestine–targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection. Nat Med. 2012;18(8):1291-7
2. Zhu Q, Egelston C, Sui Y, Gagnon S, Belyakov IM, Klinman DM, Berzofsky JA. Using three TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice. J Clin Invest. 2010; 120(2):607-16
3. Sui Y, Zhu Q, Gagnon S, Dzutsev A, Belyakov IM., Terabe M, Vaccari M, Venzon D, Klinman D, Strober W, Kelsall B, Franchini G, Berzofsky JA. Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques. Proc Natl Acad Sci USA. 2010; 107(21):9843-8
4. Zhu Q, Egelston C, Vivekanandhan A, Klinman DM, Uematsu S, Akira S, Belyakov IM, Berzofsky JA*. Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccines. Proc Natl Acad Sci USA. 2008; 105(42):16260-5
5. Hall JA, Bouladoux N, Sun CM, Wohlfert EA, Blank RB, Zhu Q, Grigg ME, Berzofsky JA, Belkaid Y. Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses. Immunity. 2008; 29(2):637-49
6. Zhu Q, Thomson CW, Rosenthal KL, McDermott M, Collins SM, Gauldie J. Immunization with adenovirus at the large intestinal mucosa as an effective vaccination strategy against sexually transmitted viral infection. Mucosal Immunol. 2008;1(1):78-88
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