Boghossian, Ardemis - École polytechnique fédérale de Lausanne EPFL - Institute of Chemical Sciences and Engineering

个人简介

Education Postdoc, Department of Chemical Engineering, California Institute of Technology (Caltech), 2012-2014 Ph.D. in Chemical Engineering, Massachusetts Institute of Technology (MIT), 2012 Minor: Materials Science and Engineering, Electrical Engineering B.S.E. in Chemical Engineering, University of Michigan - Ann Arbor, 2007 Minor: Mathematics Selected Honors & Awards Assistant Professor (AP) Energy Career Grant Award, 2014 NIH Postdoctoral Fellowship (top 1%), 2014 Making and Designing Materials Engineering Competition (MADMEC) Finalist, 2011 National Defense Science & Engineering Graduate (NDSEG) Fellowship, 2009 SMART Fellowship (funds declined), 2009 NSF Graduate Research Honorable Mention, 2009 Frederick A.L. Holloway ’39 Fellowship, 2007 Carls Foundation Scholarship, 2003

研究领域

Ardemis Boghossian has been appointed Tenure Track Assistant Professor at the Institute of Chemical Sciences and Engineering (ISIC) of the École Polytechnique Fédérale de Lausanne (EPFL). She received her Bachelor of Science in Engineering (B.S.E.) degree in Chemical Engineering from the University of Michigan in 2007. In 2012, she graduated from the Massachusetts Institute of Technology (MIT) with a doctoral degree (Ph.D.) in Chemical Engineering under the supervision of Michael S. Strano. Her graduate work focused on applied nanotechnology, where she engineered nanoparticles that interface with light-harvesting, biological constructs to enhance solar energy conversion. She also developed algorithms for quantifying stochastic fluctuations in fluorescence from single-molecule, nanotube-based biosensors. She continued her research career as a postdoctoral fellow in the Frances H. Arnold laboratory at the California Institute of Technology (Caltech) as a protein engineer, applying methods of directed evolution to engineer cells that can electronically interface with electrodes. At EPFL, Professor Boghossian implements a highly interdisciplinary approach to addressing fundamental challenges and developing novel technologies that exploit the synergy between nanotechnology and synthetic biology. Through her focal points in the fields of optoelectronics and protein engineering, she contributes new biological and biochemical methods for the production of durable hybrid nanomaterials for energy and biosensing applications.

近期论文

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Spatiotemporal Intracellular Nitric Oxide Signaling Captured Using Internalized, Near-infrared Fluorescent Carbon Nanotube Nanosensors Z. W. Ulissi, F. Sen, X. Gong, S. Sen, N. Iverson, A. A. Boghossian, L. C. Godoy, G. N. Wogan, D. Mukhopadhyay, and M. S. Strano in Nano Letters 14. 4887-4894, 2014. Plant Nanobionics Approach to Augment Photosynthesis and Biochemical Sensing J. P. Giraldo, M. P. Landry, S. M. Faltermeier, T. P. McNicholas, N. Iverson, A. A. Boghossian, N. F. Reuel, A. J. Hilmer, F. Sen, J. A. Brew, M. S. Strano in Nature Materials 13, 400-408, 2014. Molecular Recognition Using a Corona Complex Made of Artificial Polymers Adsorbed on Carbon Nanotubes J. Q. Zhang, M. P. Landry, P. W. Barone, J. H. Kim, S. Lin, Z. W. Ulissi, D. Lin, B. Mu, A. A. Boghossian, A. J. Hilmer, A. Rwei, A. C. Hinckley, S. Kruss, M. A. Shandell, N. Nair, S. Blake, F. Sen, S. Sen, R. G. Croy, D. Li, K. Yum, J. H. Ahn, H. Jin, D. A. Heller, J. M. Essigmann, D. Blankschtein, M. S. Strano in Nature Nanotechnology 8, 959-968, 2013. Application of Nanoparticle Antioxidants to Enable Hyperstable Chloroplasts for Solar Energy Harvesting A. A. Boghossian, S. Sen, B.M. Gibbons, F. Sen, J. P. Giraldo, S. M. Faltermeier, C. T. Zhang, J. Q. Zhang, M. S. Strano in Advanced Energy Materials 3, 7, 881-893, 2013. The Effect of Reductive Dithiothreitol and Trolox on Nitric Oxide Quenching of Single Walled Carbon Nanotubes S. Sen, F. Sen, A. A. Boghossian, J. Q. Zhang, M. S. Strano in Journal of Physical Chemistry C 117, 1, 593-602, 2013. Observation of Oscillatory Surface Reactions of Riboflavin, Trolox, and Singlet Oxygen Using Single Carbon Nanotube Fluorescence Spectroscopy A. A, Boghossian*, F. Sen*, S. Sen, Z. W. Ulissi, J.Q. Zhang, M. S. Strano in ACS Nano 6, 12, 10632–10645, 2012. NORSE: Noise Reduction and State Evaluator for High Frequency Single Event Traces N.F. Reuel, P. Bojo, J. Q. Zhang, A. A. Boghossian, J. H. Ahn, J. H. Kim, M. S. Strano in Bioinformatics 28, 2, 296-297, 2012. Transduction of Glycan-Lectin Binding Using Near-Infrared Fluorescent Single-Walled Carbon Nanotubes for Glycan Profiling N. F. Reuel, J. H. Ahn, J. H. Kim, J. Q. Zhang, A. A. Boghossian, L. K. Mahal, M. S. Strano in Journal of the American Chemical Society 133, 44, 17923-17933, 2011. Single-Molecule Detection of H(2)O(2) Mediating Angiogenic Redox Signaling on Fluorescent Single- Walled Carbon Nanotube Array J. H. Kim, C. R. Patra, J. R. Arkalgud, A. A. Boghossian, J. Q. Zhang, J. H. Han, N. F. Reuel, J. H. Ahn, D. Mukhopadhyay, M. S. Strano in ACS Nano 5, 10, 7848-7857, 2011. Biomimetic Strategies for Solar Energy Conversion: A Technical Perspective A. A. Boghossian, M. H. Ham, J. H. Choi, M. S. Strano in Energy & Environmental Science 4, 10, 3834-3843, 2011. The Chemical Dynamics of Nanosensors Capable of Single-Molecule Detection A. A. Boghossian, J. Q. Zhang, F. T. Le Floch-Yin, Z. W. Ulissi, P. Bojo, J. H. Han, J. H. Kim, J. R. Arkalgud, N. F. Reuel, R. D. Braatz, M. S. Strano in Journal of Chemical Physics 135, 8, 084124, 2011. Applicability of Birth-Death Markov Modeling for Single-Molecule Counting Using Single-Walled Carbon Nanotube Fluorescent Sensor Arrays Z. W. Ulissi, J. Q. Zhang, A. A. Boghossian, N. F. Reuel, S. F. E. Shimizu, R. D. Braatz, M. S. Strano in Journal of Physical Chemistry Letters 2, 14, 1690-1694, 2011. Near-Infrared Fluorescent Sensors based on Single-Walled Carbon Nanotubes for Life Sciences Applications A. A. Boghossian, J. Q. Zhang, P. W. Barone, N. F. Reuel, J. H. Kim, D. A. Heller, J. H. Ahn, A. J. Hilmer, A. Rwei, J. R. Arkalgud, C. T. Zhang, M. S. Strano in ChemSusChem 4, 7, 848–863, 2011. Label-Free, Single Protein Detection on a Near-Infrared Fluorescent Single-Walled Carbon Nanotube/Protein Microarray Fabricated by Cell-Free Synthesis J. H. Ahn, J. H. Kim, N. F. Reuel, P. W. Barone, A. A. Boghossian, J. Q. Zhang, H. Yoon, A. C. Chang, A. J. Hilmer, M. S. Strano in Nano Letters 11, 7, 2743–2752, 2011. Peptide Secondary Structure Modulates Single-Walled Carbon Nanotube Fluorescence as a Chaperone Sensor for Nitroaromatics D. A. Heller, G. W. Pratt, J. Q. Zhang, N. Nair, A. J. Hansborough, A. A. Boghossian, N. F. Reuel, P. W. Barone, M. S. Strano in PNAS of the United States 108, 21, 8544–8549, 2011. Dynamic and Reversible Self-Assembly of Photoelectrochemical Complexes Based on Lipid Bilayer Disks, Photosynthetic Reaction Centers, and Single-Walled Carbon Nanotubes A. A. Boghossian, J. H. Choi, M. H. Ham, M. S. Strano in Langmuir 27, 5, 1599–1609, 2011. Single Molecule Detection of Nitric Oxide Enabled by d(AT)(15) DNA Adsorbed to Near Infrared Fluorescent Single-Walled Carbon Nanotubes A. A. Boghossian*, J. Q. Zhang*, P. W. Barone, A. Rwei, J. H. Kim, D. H. Lin, D. A. Heller, A. J. Hilmer, N. Nair, N. F. Reuel, M. S. Strano in Journal of the American Chemical Society 133, 3, 567 – 581, 2011. Periplasmic Binding Proteins as Optical Modulators of Single-Walled Carbon Nanotube Fluorescence: Amplifying a Nanoscale Actuator H. Yoon, J. H. Ahn, P. W. Barone, K. Yum, R. Sharma, A. A. Boghossian, J. H. Han, M. S. Strano in Angewandte Chemie 50, 8, 1828–1831, 2011. Photoelectrochemical Complexes for Solar Energy Conversion That Chemically and Autonomously Regenerate A. A. Boghossian*, M. H. Ham*, J. H. Choi.*, E. S. Jeng, R. A. Graff, D. A. Heller, A. C. Chang, A. Mattis, T. H. Bayburt, Y. V. Grinkova, A. S. Zeiger, K. J. Van Vliet, E. K. Hobbie, S. G. Sligar, C. A. Wraight, M. S. Strano in Nature Chemistry 2, 11, 929 – 936, 2010. Detection of Single-Molecule H(2)O(2) Signalling from Epidermal Growth Factor Receptor Using Fluorescent Single-Walled Carbon Nanotubes H. Jin, D. A. Heller, M. Kalbacova, J. H. Kim, J. Q. Zhang, A. A. Boghossian, N. Maheshri, M. S. Strano in Nature Nanotechnology 5, 4, 302 – U81, 2010.