个人简介
1989年本科毕业于北京师范大学化学系，1992年硕士研究生毕业于南开大学化学系物理有机化学专业，并分配到中国医学科学院药物研究所工作，一直从事仿制药以及创新药物研究与开发。2009年2月至2010年2月在美国特拉华大学 (University of Delaware)化学与生化系做访问学者，从事生物活性天然产物的结构改造与全合成工作。2010年3月至4月，在美国全球结核病药物研发联盟(Global TB Alliance) 见习工作，负责全球抗结核新药研发的项目协调和管理。自1992年以来，主要从事药物化学、新药研发、不对称有机合成等方面的研究工作。
近期论文
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1. Dongfeng Zhang, Yu Lu, Kai Liu, Binna Liu, Jingbin Wang, Gang Zhang, Hao Zhang, Yang Liu, Bin Wang, Meiqin Zheng, Lei Fu, Yanyan Hou, Ningbo Gong, Yang Lv, Chun Li, Christopher B. Cooper, Anna M. Upton, Dali Yin, Zhenkun Ma,* and Haihong Huang*. Identification of Less Lipophilic Riminophenazine Derivatives for the Treatment of Drug-Resistant Tuberculosis. J. Med. Chem. 2012; 55(19):8409-8417.
2. Feng Zhang, Bei Han, Peng Li, Ziyun Lin, Dali Yin, Yan Li, Jialiang Zhong and Haihong Huang*. Design, Synthesis and Hepatoprotective Activity of Analogs of the Natural Product Goodyeroside A. Molecules. 2013; 18: 1933-1948.
3. LU Chen-shu, TANG Ke, LI Yan, JIN Bo, YIN Da-li, MA Chen, CHEN Xiao-guang*, HUANG Hai-hong*. Synthesis and in vitro antitumor activities of novel benzyl urea analogues of sorafenib. Acta Pharmaceutica Sinic. 2013; 48 (5): 709−717.
4. Bei Han, Jinglong Liu, Yi Huan, Peng Li, Qi Wu, Ziyun Lin, Zhufang Shen, Dali Yin, Haihong Huang*. Design, synthesis and primary activity of thiomorpholine derivatives as DPP-IV inhibitors. Chinese Chemical Letters. 2012; 23:297-300.
5. Yuli LI, Chunlin Zhang, Dongfeng Zhang, Yu Lu, Bin Wang, Meiqin Zheng, Chun Li, Dali Yin, Haihong Huang *. Synthesis and anti-tubercular activity of novel alkyl substituted riminophenazine derivatives. Acta Pharmaceutica Sinic. 2012; 47 (6): 745−754.
6. Chun Lin Zhang, Dong Feng Zhang, Hong Yi Zhao, Zi Yun Lin, Hai Hong Huang*. A facile protocol for N-Cbz protection of amines in PEG-600. Chinese Chemical Letters. 2012; 23:789-792.
7. Binna Liu, Kai Liu, Yu Lu, Dongfeng Zhang, Tianming Yang, Xuan Li, Chen Ma, Meiqin Zheng, Bin Wang, Gang Zhang, Fei Wang, Zhenkun Ma*, Chun Li, Haihong Huang and Dali Yin*. Systematic Evaluation of Structure-Activity Relationships of the Riminophenazine Class and Discovery of a C2 Pyridylamino Series for the Treatment of Multidrug-Resistant Tuberculosis. Molecules. 2012; 17:4545-4559.
8. Yu Lu*, Meiqin Zheng, Bin Wang, Lei Fu, Weijie Zhao, Peng Li, Jian Xu, Hui Zhu, Haixia Jin, Dali Yin, Haihong Huang, Anna M. Upton and Zhenkun Ma. Clofazimine Analogs with Efficacy against Experimental Tuberculosis and Reduced Potential for Accumulation. Antimicrob. Agents Chemother. 2011; 55 (11): 5185-5193.
9. Gang Zhang, Hao Zhang, Xiaojian Wang, Chun Li, Haihong Huang and Dali Yin*. Synthesis of New Riminophenazines with Pyrimidine and Pyrazine Substitution at the 2-N Position. Molecules. 2011; 16:6985-6991.
10. Haihong Huang, Christopher G. Nelson, Douglass F. Taber*. Potassium hydride in paraffin: a useful base for Williamson ether synthesis. Tetrahedron Letters. 2010; 51(27): 3545-3546.
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