孙平华 - 暨南大学

个人简介

教育背景： 1995.9-1999.6 沈阳药科大学药学系，理学学士 1999.9-2002.6 沈阳药科大学药物化学专业，理学硕士 2006.9-2010.6 暨南大学生物医药工程专业，医学博士 2013.3-2014.3 美国南弗罗里达大学药学院/Moffitt癌症研究所博士后工作背景： 2002.7至今，暨南大学药学院药物化学教研室，助教，讲师，副教授

研究领域

1. 抗感染药物的设计与合成； 2. 天然活性产物的全合成及结构修饰； 3. 计算机辅助药物设计与虚拟筛选。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Jiasuo Gao, Yiqun Chang, Jialiang Guo, Guochao Liao, Pinghua Sun*. Design and prediction of new anticoagulants as a selective Factor IXa inhibitor via three-dimensional quantitative structure-property relationships of amidinobenzothiophene derivatives. Drug Des. Dev. Ther. 2015, 9, 1743-1759. 2. Junxia Zheng, Hao Kong, James M. Wilson, Jialiang Guo, Yiqun Chang, Mengjia Yang, Gaokeng Xiao, Pinghua Sun*. Insight into the interactions between novel isoquinolin-1,3-dione derivatives and cyclin-dependent kinase 4 combining QSAR and molecular docking. Plos One, 2014, 9, e93704. 3. Lingxing Shan, Pinghua Sun*, Baoqin Guo, Xingjun Xu, Zhiqiang Li, Jiazhi Sun, Shufeng Zhou, Weimin Chen. Synthesis and antibacterial activities of acylide derivatives bearing an aryl-tetrazolyl chain. Drug Des. Dev. Ther. 2014, 8, 1515-1525. 4. Ruan Zhi-Xiong, Huangfu De-Sheng, Xu Xingjun, Sun Pinghua*, Chen Wei-Min. 3D-QSAR and molecular docking for the discovery of ketolides derivatives. Expert. Opin. Drug Discov. 2013, 8, 427-444. 5. Guo Jialiang, Zhang Qiaoxuan, Peng Yongbo, Liu Zhenghua, Rao Longyi, He Ting, Crommen Jacques, Sun Pinghua*, Jiang Zhengjin. A facile and efficient one-step strategy for the preparation of b-cyclodextrin monoliths. J. Sep. Sci. 2013, 36, 2441-2449. 6. Ruan Zhixiong, Huangfu Desheng, Sun Pinghua*, Chen Weimin. Molecular modeling studies on 3,4-dihydroquinazolines as trypanothione reductase inhibitors using 3D-QSAR and docking approaches. Med. Chem. Res. 2013, 22, 3541-3555. (co-corresponding author) 7. Zheng Junxia, Xiao Gaokeng, Guo Jialiang, Zheng Yang, Gao Hao, Zhao Suqing, Zhang Kun, Sun Pinghua*. Exploring QSARs for inhibitory activity of 5-lipoxygenase (5-LO) inhibitors by CoMFA and CoMSIA. Chem. Biol. Drug Des. 2011, 78, 314-321. 8. Zheng Junxia, Xiao Gaokeng, Guo Jialiang, Rao Longyi, Chao Wei, Zhang Kun, Sun Pinghua*. Three-dimensional quantitative structure-activity relationship of pyrrolopyridinone as cell division cycle kinase inhibitors by CoMFA and CoMSIA. J. Mol. Model, 2011, 17, 2113-2130. 9. Qian Chuiwen, Zheng Junxia, Xiao Gaokeng, Guo Jialiang, Yang Zhaoqi, Huang Li, Chao Wei, Rao Longyi, Sun Pinghua*. 3D-QSAR studies on thiazolidin-4-one S1P1 receptor agonists by CoMFA and CoMSIA. Int. J. Mol. Sci. 2011, 12, 6502-6516. 10. Ai Yong, Wang Shaoteng, Tang Chu, Sun Pinghua*, Song Fajun. 3D-QSAR and docking studies on pyridopyrazinones as BRAF inhibitors. Med. Chem. Res. 2011, 20, 1298-1317. 11. Zheng Junxia, Wu Zhiwei, Dai Mibei, Xu Zhihui, Li Xiaomei, Zhu Shanshan, Lin Chuyun, Hu Peijian, Zhang Luo, Huang Huarong, Zhao Suqing, Zhang Kun, Sun Pinghua*. Quantitative structure activity relationship studies on a novel indolediones as long chain fatty acid elongase 6 (ELOVL6) inhibitors. Lett. Drug Des. Discov. 2011, 8, 422-429. 12. Wang Shaoteng, Ai Yong, Tang Chu, Song Fajun, Sun Pinghua*. 3D-QSAR and docking studies of 4-morpholinopyrrolopyrimidine derivatives as potent mTOR inhibitors. Lett. Drug Des. Discov. 2011, 8, 339-354. 13. Ai Yong, Wang Shaoteng, Sun Pinghua*, Song Fajun. Molecular Modeling Studies of 4,5-Dihydro-1H-pyrazolo[4,3-h] quinazoline Derivatives as Potent CDK2/Cyclin A Inhibitors Using 3D-QSAR and Docking. Int. J. Mol. Sci. 2010, 11, 3705-3724. 14. Ai Yong, Song Fa-Jun, Wang Shao-Teng, Sun Qiang, Sun Pinghua*. Molecular modeling studies on 11H-dibenz[b,e]azepine and dibenz[b,f][1,4]oxazepine derivatives as potent agonists of the human TRPA1 receptor. Molecules, 2010, 15, 9364-9379.

学术兼职

美国科学会会员（AAAS）、美国化学会会员（ACS）、中国药学会会员、中国生物医学工程学会会员和广东省药学会药物化学专业委员会委员；《中国医药工业杂志》、《中国药学杂志》、《中国药物化学杂志》、《Drug Design Development and Therapy》、《Medicinal Chemistry Research》、《Letters in Drug Design and Discovery》、《Current Computer-aided Drug Design》等期刊审稿人。