李敏一 - 暨南大学

个人简介

2004.07-2005.06 北京大学深圳研究生院化学基因组学实验室研究实习员 2005.07-2012.09 中国科学院南海海洋研究所海洋生物资源可持续利用院重点实验室研究实习员、助理研究员。 2012.10-至今暨南大学药学院海洋药物研究中心副教授。 2009.04-2009.10 德国Philipps-Universität Marburg大学的药用生物学和生物技术科学研究所访问学者。

研究领域

1. 红树植物来源的活性先导化合物发现、作用机制与构效关系； 2. 重要海洋天然产物的生物合成和化学生态学功能研究。

近期论文

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1. Li MY., Tian Y., Shen L., Buettner R., Li HZ., Liu L., Yuan YC., Xiao Q., Wu J.*, Jove R*. 3-O-methylthespesilactam, a new small-molecule anticancer pan-JAK inhibitor against A2058 human melanoma cells,Biochem. Pharmacol., 2013, 86(10), 1411-1418. 2. Li MY., Xiao Q., Pan JY., Wu J*. Natural Products from Semi-Mangrove Flora: Source, Chemistry and Bioactivities, Nat. Prod. Rep., 2009, 26(2): 281–298.) 3. Li MY., Yang SX., Pan JY., Xiao Q., Satyanandamurty T., Wu J*. Moluccensins A-G, Phragmalins with a Conjugated C-30 Carbonyl Group from a Krishna Mangrove, Xylocarpus moluccensis. J. Nat. Prod., 2009, 72(9): 1657–1662. 4. Li MY., Yang XB., Pan JY., Feng G., Xiao Q., Sinkkonen J., Satyanandamurty T., Wu J*. Granatumins A-G, Limonoids from the Seeds of a Krishna Mangrove, Xylocarpus granatum. J. Nat. Prod., 2009, 72(12): 2110–2114. 5. Li MY.*, Xiao Q.,Satyanandamurty T., Wu J*. Limonoids with an Oxygen Bridge between C(1) and C(29) from the Seeds of aKrishna Mangrove, Xylocarpus granatum. Chem. Biodivers., 2014, 11(2): 262-275. 6. Li MY., Zhang J., Feng G., Satyanandamurty T., Wu J.* Khayasin and 2'S-Methylbutanoylproceranolide: Promising Candidate Insecticides for the Control of the Coconut Leaf Beetle, Brontispa longissima., J. Pestic. Sci., 2011, 36 (1): 22-26. 7. Li J., Li MY.*, Feng G., Zhang J., Karonen M., Sinkkonen J., Satyanandamurty T., Wu J*. Moluccensins R-Y, Limonoids from the Seeds of a Mangrove, Xylocarpus moluccensis. J. Nat. Prod., 2012, 75(7), 1277-1283. 8. Chen WP., Shen L., Li MY.*, Xiao Q.,Satyanandamurty T., Wu J*. Absolute configurations of new limonoids from a Krishna mangrove, Xylocarpus granatum. Fitoterapia, 2014, 94: 108-113. 9. Li J., Li MY., Bruhn T., Felix ZK., Xiao Q., Pedpradab P., Wu J.*, Bringmann G*. Thaixylomolins A-C: LimonoidsFeaturing Two New Motifs fromthe Thai Xylocarpus moluccensis. Org. Lett., 2013, 15(14): 3682-3685. 10. Li J., Li MY., Bruhn T., Goetz D. C. G., Xiao Q., Satyanandamurty T., Wu J.*, Bringmann G*. Andhraxylocarpins A-E: Structurally Intriguing Limonoids from the True Mangroves Xylocarpus granatum and Xylocarpus moluccensis. Chem-Eur. J., 2012, 18(45): 14342-14351.