韩海 - 暨南大学

个人简介

1999年毕业于华西医科大学药学专业，获学士学位。2002年毕业于四川大学华西药学院药物分析学专业，获硕士学位。2002年起至今在暨南大学药学院工作。

研究领域

1. 二维HPLC系统的构建及其在体内药物分析中的应用 2. D-氨基酸的体内分布及生理功能研究 3. 体内微量手性药物分析

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Kenji Hamase, Yurika Miyoshi, Kyoko Ueno, Hai Han, Junzo Hirano, Akiko Morikawa, Masashi Mita, Tsuneaki Kaneko, Wolfgang Lindner and Kiyoshi Zaitsu. Simultaneous determination of hydrophilic amino acid enantiomers in mammalian tissues and physiological fluids applying a fully automated micro-two-dimensional high-performance liquid chromatographic concept, Journal of Chromatography A, 1217 (2010) 1056-1062. 2. Hai Han, Yurika Miyoshi, Kyoko Ueno, Chieko Okamura, Yosuke Tojo, Masashi Mita, Wolfgang Lindner, Kiyoshi Zaitsu, Kenji Hamase. Simultaneous determination of D-aspartic acid and D-glutamic acid in rat tissues and physiological fluids using a multi-loop two-dimensional HPLC procedure, Journal of Chromatography B, 879 (2011) 3196-3202. 3. Hai Han, Yurika Miyoshi, Tsubasa Oyama, Ryoko Konishi, Masashi Mita, Kenji Hamase. Enantioselective micro-2D-HPLC determination of aspartic acid in the pineal glands of rodents with various melatonin contents,Journal of Separation Science, 34 (2011) 2847-2853. 4.Yurika Miyoshi, Reiko Koga, Tsubasa Oyama, Hai Han, Kyoko Ueno, Kei Masuyama, Yusuke Itoh, Kenji Hamase. HPLC analysis of naturally-occurring free D-amino acids in mammals, Journal of Pharmaceutical and Biomedical Analysis, 69 (2012) 42-49. 5. Yurika Miyoshi, Yosuke Tojo, Hai Han, Masashi Mita and Kenji Hamase.Development of a Simultaneous Two-dimensional Micro-HPLC Analysis System for the Chiral Amino Acid Metabolomics Study in Mammals, BUNSEKI　KAGAKU, 61(2012) 489-500. 6. Hai Han*, Qi-Qin Wang, Hui-Hui Wu, Huan Wang. Establishment and Application of an Automated Chiral Two-dimensional High Performance Liquid Chromatography Method for Bio-analysis of D-Acidic Amino Acids, Chinese Journal of Analytical Chemistry, 42 (2014) 891-898. 7. Qiqin Wang, Jun Feng, Hai Han, Peijie Zhu, Huihui Wu, Maria Luisa Marina, Jacques Crommen, Zhengjin Jiang. Enantioseparation of N-derivatized amino acids by micro-liquid chromatography using carbamoylated quinidine functionalized monolithic stationary phase, Journal of Chromatography A, 1363 (2014) 207-215. 8. Hai Han, Yurika Miyoshi, Masashi Mita, Ryuichi Konno, Kenji Hamase. Changes in D-aspartic acid and D-glutamic acid levels in the tissues and physiological fluids of mice with various D-aspartate oxidase activities, Journal of Pharmaceutical and Biomedical Analysis, doi:10.1016/j.jpba.2015.05.013 9. Qiqin Wang, Elena Sánchez-Lópezb, Hai Han, Huihui Wu, Peijie Zhu, Jacques Crommen, Maria Luisa Marina, Zhengjin Jiang. Separation of N-derivatized di- and tri-peptide stereoisomers by micro-liquid chromatography using a quinidine-based monolithic column - Analysis of L-carnosine in dietary supplements, Journal of Chromatography A, doi:10.1016/j.chroma.2015.09.016 10. Hai Han, Yurika Miyoshi, Yosuke Tojo, Wolfgang Lindner, Kenji Hamase, Simultaneous micro-2D-HPLC deter-mination of D-aspartic acid and D-glutamic acid in the tissues and physiological fluids of various strains of mice, 22th　International Symposium on Chirality (ISCD-22 (Chirality 2010)) (Hokkaido, Japan, 2010 July)