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个人简介

1985年7月华东化工学院(现华东理工大学)生物化学专业毕业,获学士学位;1991年3月天津轻工业学院(现天津科技大学)发酵工程专业毕业,获硕士学位;1997年7月华南理工大学发酵工程专业毕业,获博士学位;1997-1999年在华南农业大学博士后流动站从事博士后科研工作,1999年出站。先后在云南工学院(现昆明理工大学)、天津轻工业学院、暨南大学从事教学和生物技术药物科研、开发工作。

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1. Qing Zheng, Zhifeng Huang, Xiaoping Wu∗, Zhijian Su, Hua Xu, Wen Zhao, Yadong Huang, Xiaokun Li. Site-directed chemical modification of recombinant human aFGF Mutant with polyethylene glycol, Chinese Chemical letters, 2005,16(8):1013-1016 . 2. Xiaoping Wu, Xiaokun Li, Zhijian Su, Qing Zheng*, Hua Xu, Sixian Wu, Ya Feng and Wen Zhao. Expression and Purification of Soluble Non-Fusion Vasostatin in Escherichia coli. Protein & Peptide Letters, 2005, 12(7): 659-662. 3. Zhifeng Huang, Qing Zheng, Xiaoping Wu, Zhijian Su, Hua Xu,Yi Tan, Wenke Feng, Xiaokun Li∗, Lu Cai. Enhanced protection of modified human acidic fibroblast growth factor with polyethylene glycol against ischemia/ reperfusion- induced retinal damage in rats, Toxicology Letters, 2007, 170(2): 146 -156. 4. Xiaoping Wu, Xiaokun Li, Yaoying Zeng, Qing Zheng, Sixian Wu. Site-directed PEGylation of human basic fibroblast growth factor. Protein Expression and Purification, 2006, 48(1): 24-27. 5. Xiaoping Wu, Zhijian Su, Xiaokun Li, Qing Zheng, Yadong Huang, Hui Yuan. High-level expression and purification of a nonmitogenic form of human acidic fibroblast growth factor in Escherichia coli. Protein Expression and Purification, 2005, 42(1):7-11. 6. Zhijian Su, Yadong Huang, Quannan Zhou, Zhiling Wu, Xiaoping Wu, Qing Zheng, Changcai Ding and Xiaokun Li. High-level expression and purification of human epidermal growth factor with SUMO fusion in Escherichia coli. Protein Peptide Letters. 2006,13(8):785-792. 7. Xu H, Yang JN, Li XK, Zheng Q, Zhao W, Su ZJ, Huang YD. Retina Protective Effect of Acidic Fibroblast Growth Factor after Canceling Its Mitogenic Activity. Journal of ocular pharmacology and therapeutics. 2008, 24(5): 445-451. 8. Xu H, Hai GF, Xiang JZ, Yao CC, Zheng Q, Zhang QH, Hong H. Protective effect of non-mitogenic human acidic fibroblast growth factor on hepatocyte injury. Hepatology Research 2007; 37: 836–844. 9. WU Xiao-Ping, SU Zhi-jian, ZHENG Qing, WU Si-xian, XU Hua, Zhao Wen, LI Xiao-Kun. A Convenient and Effective Approach for Gene Synthesis of Human Platelet Factor2. Journal of China Pharmaceutical University, 2005,36(6):590-59. 10. WU Xiao-Ping, SU Zhi-jian, ZHENG Qing, WU Si-xian, FENG Ya, QU Hong-yan, XU Hua, LI Xiao-Kun Expression and Purification of a hbFGF Lacking Nuclear Localization Signal, Journal of China Pharmaceutical University 2005,36(3):272-27. 11. WU Xiao-ping LI Xiao-kun SU Zhi-jian ZHENG Qing WU Si-xian XU Hua QU Hong-yan. Expression and Purification of Basic Fibroblast Growth Factor Mutant with Reduced Mitogenic Activity,China Biotechnology, 2005, 25 (2) :49-52. 12. 郑青, 郭建红, 周仲楼, 曾庆平, 赵文. 转铁蛋白对青蒿琥酯体外抗肿瘤活性的增效作用研究,中草药,2008,39(6):887-889. 13. 郑青, 彭菲, 吴晓萍, 苏志坚, 李校堃. nmhaFGF对人乳腺癌细胞增殖的影响及相关机制. 药学学报. 2006, 41(3): 263-267. 14. 郑青, 彭菲, 苏志坚, 吴晓萍, 许华, 李校堃. haFGF和nm-haFGF过表达对乳腺肿瘤细胞增殖及c-fos、c-jun mRNA表达的影响. 中国药理学通报. 2006, 22(4): 402-7. 15. 郑 青, 高树生, 彭菲, 李黎, 许华, 刘蓓, 李校堃. bFGF-胶原蛋白海绵对宫颈糜烂的治疗作用,山东医药,2006,46(11):41-42. 16. 人酸性成纤维细胞生长因子突变体表达与修饰, 华南理工大学学报,2005,33(1):88-91. 17. 郑青, 汪小凤, 吴晓萍, 许华, 张齐好, 苏志坚, 李校堃. haFGF突变体促细胞增殖活性降低及其机制,中国病理生理杂志,2005, 21(3):446-448. 18. 汪小凤, 郑青*, 蔡绍晖, 吴晓萍, 许华, 赵文, 苏志坚, 李校堃, 张敏. 非促分裂型aFGF改构体的受体结合特性及其对NIH3T3细胞MAPK信号通路的影响,中国药科大学学报,2005,36(2):179-182. 19. 郑青, 汪小凤, 吴晓萍, 许华, 苏志坚, 冯雅, 李校堃. 酸性成纤维细胞生长因子对人脐静脉血管内皮细胞一氧化氮生成的影响,暨南大学学报,2005, 26(4):455-459. 20. 郑青, 湛敏, 许华, 吴晓萍, 李校堃. nmhaFGF对SD大鼠缺血再灌注视网膜SOD、MDA、NO的影响,山东医药,2005,45(34):15-16.

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