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Xuanyue Ma#, Liuren Li#, Ziming Li#, Zhengyi Huang, Yaorong Yang, Peng Liu, Daji Guo, Yueyao Li, Tianying Wu, Ruixiang Luo, Junyu Xu, Wen-Cai Ye*, Bin Jiang*, Lei Shi*. eEF2 in the prefrontal cortex promotes excitatory synaptic transmission and social novelty behavior.(2022) EMBO Reports. 2022 Aug 22. e54543
Francesco Chiavaioli*, Desiree Santano Rivero, Ignacio Del Villar*, Abián B Socorro‐Leránoz, Xuejun Zhang, Kaiwei Li, Enrique Santamaría, Joaquín Fernández-Irigoyen, Francesco Baldini, Daniel LA van den Hove, Lei Shi, Wei Bi, Tuan Guo*, Ambra Giannetti, Ignacio R Matias. Ultrahigh Sensitive Detection of Tau Protein as Alzheimer's Biomarker via Microfluidics and Nanofunctionalized Optical Fiber Sensors.(2022) Advanced Photonics Research. 2022 July 18. DOI:10.1002/adpr.202200044
Daji Guo#,*, Xiaoman Yang#, Ming Gao#, Xiaoqing Chen, Yanping Tang, Lingling Shen, Keshen Li*, Lei Shi*. Deficiency of autism-reulated gene Dock4 leads to impaired spatial memory and hippocampal function in mice at late middle age.(2022) Cellular and Molecular Neurobiology. 2022 May 30. DOI:10.1007/s10571-022-01233-4
Yanling Huang#, Yaorong Yang#, Yawen Zhao, Daji Guo, Linxi Chen, Lei Shi*, Geyang Xu*. DOCK4 regulates ghrelin production in gastric X/A-like cells.(2022) Journal of Endocrinological Investigation. 2022 Jul.45(7):1447-1454
Rui Zheng#, Yonglan Du#, Xintai Wang, Tailin Liao, Zhe Zhang, Na Wang, Xiumao Li, Ying Shen, Lei Shi, Jianhong Luo*, Jun Xia*, Ziyi Wang*, Junyu Xu*. KIF2C regulates synaptic plasticity and cognition in mice through dynamic microtubule depolymerization.(2022) eLife. 2022 Feb 9. 11:e72483
Yu-wei Pan#, Dong-ping Wu, Hua-feng Liang, Gen-yun Tang, Chun-lin Fan, Lei Shi, Wen-cai Ye, Man-mei Li*. Total Saponins of Panax notoginseng Activate Akt/mTOR Pathway and Exhibit Neuroprotection in vitro and in vivo against Ischemic Damage.(2021) Chinese Journal of Integrative Medicine. 2022 May. 28(5):410-418
Hanlin Xiao#, Qinghua Zhang, Peiyun Zhong, Genyun Tang, Lijun Tao, Zhengyi Huang, Daji Guo, Yumei Liao, Yinghui Peng, Zhen-Long Wu, Ying Wang, Wen-Cai Ye,* and Lei Shi*. Securinine Promotes Neuronal Development and Exhibits Antidepressant-like Effects via mTOR Activation.(2021) ACS Chemical Neuroscience. 2021 Oct 6. 12(19):3650-3661.
Jian-Guo Song#, Wei Tang#, Xiaojun Wang, Jun-Cheng Su, Xiao-Jun Huang, Lei Shi, Wen-Cai Ye*, Ying Wang* Phloroglucinol-derived lipids from the leaves of Syzygium cumini and their neuroprotective activities.(2021) Fitoterapia. 2021 Sep. 153:104968.
Qi-Fang He#, Zhen-Long Wu#, Liuren Li, Wan-Yang Sun, Gui-Yang Wang, Ren-Wang Jiang, Li-Jun Hu, Lei Shi, Rong-Rong He, Ying Wang*, Wen-Cai Ye*. Discovery of Neuritogenic Securinega Alkaloids from Flueggea suffruticosa by a Building Blocks-Based Molecular Network Strategy.(2021) Angewandte Chemie International Edition. 2021 Sep 1. 60(36):19609-19613.
Xianman Yang#, Daji Guo#, Keshen Li, Lei Shi*. Altered postnatal developmental patterns of ultrasonic vocalizations in Dock4 knockout mice.(2021) Behavioural Brain Research. 2021 May 21. 406:113232.
Qi-Fang He, Zhen-Long Wu, Xiao-Jun Huang, Tian-Qi Xia, Genyun Tang, Wei Tang, Lei Shi, Wen-Cai Ye*, Ying Wang*. Cajanusoids A–D, Unusual Atropisomeric Stilbene Dimers with PTP1B Inhibitory Activities from the Leaves of Cajanus cajan.(2021) The Journal of Organic Chemistry. 2021 Apr 16. 86(8):5870-5882.
Hui Liu#, Xiaojun Wang#, Qiaoyun Shi#, Liuren Li, Qinghua Zhang, Zhen-Long Wu, Xiao-Jun Huang, Qing-Wen Zhang, Wen-Cai Ye, Ying Wang*, Lei Shi*. Dimeric Diarylheptanoids with Neuroprotective Activities from Rhizomes of Alpinia officinarum.(2020) ACS Omega. 2020 Apr. 22. 5(17):10167-10175.
Daji Guo#, Xiaoman Yang, Lei Shi*. Rho GTPase Regulators and Effectors in Autism Spectrum Disorders: Animal Models and Insights for Therapeutics.(2020) Cells. 2020 Mar 31. 9(4):835
Miaoqi Huang#, Chuanmei Liang#, Shengnan Li#, Jifeng Zhang, Daji Guo, Bo Zhao, Yuyang Liu, Yinghui Peng, Junyu Xu, Wei Liu, Guoqing Guo, Lei Shi*. Two autism/dyslexia linked variations of DOCK4 disrupt the gene function on Rac1/Rap1 activation, neurite outgrowth, and synapse development.(2020) Frontiers in Cellular Neuroscience. 2020 Jan 15. 13:577.
Jing Xu, Yong-lan Du, Jing-wei Xu, Xiao-ge Hu, Lin-fan Gu, Xiu-mao Li, Ping-hong Hu, Tai-lin Liao, Qiang-qiang Xia, Qi Sun, Lei Shi, Jianhong Luo, Jun Xia, Ziyi Wang* and Junyu Xu*. Neuroligin 3 regulates dendritic outgrowth by modulating Akt/mTOR signaling.(2019) Frontiers in Cellular Neuroscience. 2019 Nov 29. 13:518.
Daji Guo#, Yinghui Peng#, Laijian Wang#, Xiaoyu Sun, Xiaojun Wang, Chunmei Liang, Xiaoman Yang, Shengnan Li, Junyu Xu, Wen-Cai Ye*, Bin Jiang*, Lei Shi*. Autism-like social deficit generated by Dock4 deficiency is rescued by restoration of Rac1 and NMDA receptor function.(2019) Molecular Psychiatry. 2021 May. 26(5):1505-1519
Qiaoyun Shi#, Qianghua Zhang#, Yinghui Peng*, Xiaoqi Zhang, Ying Wang, Lei Shi*. A natural diarylheptanoid protects cortical neurons against oxygen-glucose deprivation-induced autophagy and apoptosis.(2019) Journal of Pharmacy and Pharmacology. 2019 Jul; 71(7):1110-1118. Epub 2019 Apr 25.
Xia QQ#, Xu J, Liao TL, Yu J, Shi L, Xia J, Luo JH*, Xu J*. Neuroligins Differentially Mediate Subtype-Specific Synapse Formation in Pyramidal Neurons and Interneurons.(2019) Neuroscience Bulletin. 2019 Jun; 35(3):497-506. Epub 2019 Feb 21.
Adorjan I#,*, Tyler T, Bhaduri A, Demharter S, Finszter CK, Bako M, Sebok OM, Nowakowski TJ, Khodosevich K, Møllgård K, Kriegstein AR, Shi L, Hoerder-Suabedissen A, Ansorge O, Molnár Z*. Neuroserpin expression during human brain development and in adult brain revealed by immunohistochemistry and single cell RNA sequencing.(2019) Journal of Anatomy. 2019 Sep; 235(3):543-554. Epub 2019 Jan 15.
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