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个人简介

学习经历: 1991.09-1995.07 湘潭大学,高分子化学,理学学士; 1995.09-1998.07 湘潭大学,电分析化学,理学硕士,导师为李益恒教授; 1998.09-2001.07 南开大学,有机分析化学,理学博士,导师为王琴孙教授; 2001.07-2002.07 中科院大连化物所博士后,从事毛细管电色谱与质谱的联用及其在生物样品分析中应用研究,合作导师为张玉奎院士和阎超教授; 2003.08-2005.07 德国蒂宾根大学博士后,主要从事手性分离科学研究,合作导师为国际著名的volker. Schurig教授(Journal of Chromatography A, Chirality等国际著名期刊主编) 工作经历: 2001.08-2002.06 通微(Unimicro)技术有限公司,主要负责新仪器的研发、应用以及售后技术服务; 2004.07-2007.06 英国伦敦大学King’s College研究员,主要从事微分离科学研究; 2007.02-2007.05 世界第一大制药公司Pfizer分析研发部(英国Sandwich) 合作研究科学家Collaborating Research Scientist,主要负责新分析方法的高速高分离度以及微型化研究; 2007.07-2010.07 Novartis Institutes for Biomedical Research(Horsham),Research Scientist研究员,主要负责药物候选分子的物理化学性质鉴定和筛选以及药物ADME的分析,同时还承担一定药物的分离提纯和结构鉴定工作; 2010.10-至今 暨南大学药学院 全职教授 药物分析学科带头人; 2013.09-2013.10 西班牙阿尔卡拉大学访问教授(Visting professor)。

研究领域

1. 现代色谱的理论及技术研究:包括色谱分离理论、分析仪器改进、新型色谱柱和固定相的研制、手性物质的分离和分离技术微型化和集成化的探索(聚合物整体色谱柱,毛细管电泳和电色谱); 2. 药物代谢及生物标志物/靶标研究:候选药物的理化性质的鉴定和筛选、受体/蛋白-小分子相互作用、药物/毒物的代谢动力学(ADME)分析、蛋白质组学/代谢组学方法学研究及其应用于药物靶标筛选或作用机制阐述(信号转导)的研究;

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Qianqian Duan1, Chusheng Liu1, Zhenghua Liu, Zhengyin Zhou, Weijia Chen, Qiqin Wang, Jacques Crommen, Zhengjin Jiang*, Preparation and evaluation of a novel monolithic column containing double octadecyl chains for reverse-phase micro high performance liquid chromatography, J. Chromatogr. A, 2014, 1345, 174-181. 2. Qiqin Wang1, Jun Feng1, Hai Han, Peijie Zhu, Huihui Wu, Maria Luisa Marina, Jacquse Crommen, Zhengjin Jiang*, Enantioseparation of N-derivatized amino acids by micro-liquid chromatography using carbamoylated quinidine functionalized monolithic stationary phase, J. Chromatogr. A, 2014, 1363, 207-215. 3. Qiaoxuan Zhang1, Jialiang Guo1, Feng Wang, Jacques Crommen, Zhengjin Jiang*, Preparation of a β-cyclodextrin functionalized monolith via a novel and simple one-pot approach and application to enantioseparations, J. Chromatogr. A, 2014, 1325, 147-154. 4. Xianglong Zhao1, Weijia Chen1, Zhenghua Liu, Jialiang Guo, Zhengyin Zhou, Jacques Crommen, Ruin Moaddel, Zhengjin Jiang*, A novel mixed phospholipid functionalized monolithic column for early screening of drug induced phospholipidosis risk, J. Chromatogr. A, 2014, 1367, 99-108. 5. Chusheng Liu1, Weijia Chen1, Guangxin Yuan, Yao Xiao, Jacques Crommen, Shihai Xu*, Zhengjin Jiang*, Influence of the crosslinker type on the chromatographic properties of hydrophilic sulfoalkylbetaine-type monolithic columns, J. Chromatogr. A, 2014, 1373, 73-80. 6. Guangxin Yuan1, Yongbo Peng1, Zhenghua Liu, Jieya Hong, Yao Xiao, Jialiang Guo, Norman W. Smith, Jacques Crommen, Zhengjin Jiang*, A facile and efficient strategy to enhance hydrophilicity of zwitterionic sulfoalkylbetaine type monoliths, J. Chromatogr. A, 2013, 1301, 88-97. 7. Zhengjin Jiang1*, John Reilly. Chromatography approaches for early screening of the phospholipidosis-inducing potential of pharmaceuticals, J Pharm Biomed Anal., 2012, 61, 184-190. 8. Zhengjin Jiang1*, Norman W. Smith, Zhenghua Liu, The preparation and application of Hydrophilic monolithic column, J. Chromatogr. A, 2011, 1218, 2350-2361. 9. Zhengjin Jiang1, John Reilly*, Brian Everatt, Emmanuelle Briard, A rapid vesicle electrokinetic chromatography method for the assessment of non-specific binding of potential PET ligands, J. Pharmace. Biomed. Anal., 2011, 54, 722-729. 10. Zhengjin Jiang1, Norman W. Smith*, Paul D. Ferguson, Mark R. Taylor, Hydrophilic interaction chromatography using methacrylate-based monolithic capillary column for the separation of polar analytes, Anal. Chem., 2007, 79, 1243-1250. (google引用128次) 11. Norman W. Smith1*, Zhengjin Jiang, Developments in the use and fabrication of organic monolithic phases for use with high-performance liquid chromatography and capillary electrochromatography, J. Chromatogr. A, 2008, 1184, 416-440. (google引用92次,2008-2009 top 50 cited article) 12. Zhengjin Jiang1*, Zhuohong Yang, Roderich D. Süssmuth, Norman Williams Smith, Highlighting the possible secondary interactions in the role of balhimycin and its analogues for enantiorecognition in capillary electrophoresis, J. Chromatogr. A, 2010, 1217, 1149-1156. 13. Zhengjin Jiang1*, John Reilly, Brian Everatt, Novel zwitterionic polyphosphorylcholine monolithic column for hydrophilic interaction chromatography, J. Chromatogr. A, 2009, 1216, 2439-2448. 14. Zhengjin Jiang1, Volker Schurig*, Existence of a low isoenantioselective temperature in complexation gas chromatography: Profound change of enantioselectivity of a nickel(Ⅱ) chiral selector either bonded to, or dissolved in, poly(dimethylsiloxane), J. Chromatogr. A, 2008, 1186, 262-270. 15 .Zhengjin Jiang1*, John Reilly, Brian Everatt, A method for rapidly predicting drug tissue distribution using surfactant vesicle electrokinetic chromatography, Electrophoresis, 2008, 29, 3674-3684. 16. Giuseppe Sicoli, Zhengjin Jiang, Laszlo Jicsinsky, Volker Schurig*, Modified linear dextrins (“acyclodextrins”) as new chiral selectors for the gas-chromatographic separation of enantiomers, Angew. chem. int. Ed., 2005, 44, 4092-4095. 17.Zhengjin Jiang, Vernon Jiang and Chao Yan, Editor: Yukui Zhang, CEC and its Application in Analysis of Biological Samples, Chapter 7 in Book: Modern Methods of Separation and Analysis for Biological Samples; Science Publishing Co., 2003, ISBN 7-03-011117-6. (Book) 18.一种仿生磷脂膜整体柱的制备方法及用途(已授权,授权号:ZL201210405785.1) 19.一种亲水性有机聚合物液相整体色谱柱的制备方法及应用(已授权,授权号:ZL201210405785.1) 20.一步法制备环糊精有机聚合物毛细管整体柱的方法及应用

学术兼职

1. 英国色谱协会会员; 2. Analytical Chemistry, Journal of Chromatography A,Journal of Pharmaceutical and Biomedical Analysis,Journal of Separation Science, Analytical Chimica Acta等国际期刊通讯审稿人。

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