陈卫民 - 暨南大学

个人简介

学习经历： 1979.9-1983.7 华中工学院（现华中科技大学），理学学士 1987.9-1990.6 同济医科大学，医学硕士 1995.9-1998.12 中山大学，理学博士 2001.6-2003.6 香港中文大学，Research Associate 工作经历： 1983.8-1990.5 石家庄陆军学院，教师 1990.6-2004. 6 第一军医大学，讲师、副教授、教授 2004.7- 暨南大学，教授

研究领域

1. 新型抗感染药物的设计与合成； 2. 天然活性化合物的结构修饰与活性先导物发现。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Huang, Mei-Yan(#); Lin, Jing(#); Huang, Zhi-Jian; Xu, Hong-Gui; Hong, Juan; Sun, Ping-Hua; Guo, Jia-Liang; Chen, Wei-Min(*). Design, synthesis and anti-inflammatory effects of novel 9-O-substituted-berberine derivatives, Med. Chem. Commun., 2016, DOI: 10.1039/c5md00577a. 2. Zhang, Dong-Mei(#); Xu, Hong-Gui(#); Wang, Lei; Li, Ying-Jie; Sun, Ping-Hua; Wu, Xiao-Ming; Wang, Guang-Ji; Chen, Wei-Min(*); Ye, Wen-Cai(*). Betulinic Acid and its Derivatives as Potential Antitumor Agents，Medicinal Research Reviews，2015，35（6）：1127-1155. 3. Chen, Yan(#); Ruan, Zhi-Xiong(#); Wang, Fang; Huangfu, De-Sheng; Sun, Ping-Hua; Lin, Jing; Chen, Wei-Min(*). Novel Oxazolidinone Antibacterial Analogues with a Substituted Ligustrazine C-ring Unit，Chemical Biology & Drug Design，2015，86（4）：682-690. 4. Li, Zhiqiang; Li, Qingjiang; Liu, Guo-Kai; Chen, Weimin(*); Peng, Xiao-Shui; Wong, Henry N. C.(*). Gold(I)-Catalyzed Domino Cyclization for the Synthesis of Tricyclic Chromones，Synlett，2015，26（11）：1461-1464。 5. Wang, Fang; Lin, Jing(*);Hou, Wen; Huang, Mei-Yan; Sun, Ping-Hua; Chen, Wei-Min(*). 5-Benzylidene-3,4-dihalo-furan-2-one Derivatives Inhibit Human Leukemia Cancer Cells Through Suppression of NF-kappa B and GSK-3 beta，Anti-Cancer Agents in Medicinal Chemistry，2015，15（6）：744-754。 6. Geng, Zhi-Zhong(#); Zhang, Jian-Jun(#); Lin, Jing(*); Huang,Mei-Yan; An,Lin-Kun; Zhang,Hong-Bin; Sun,Ping-Hua; Ye,Wen-Cai; Chen, Wei-Min(*). Novel cajaninstilbene acid derivatives as antibacterial agents, European Journal of Medicinal Chemistry，2015，100:235-245. 7. Hu, Yu-Quan; Li, Chen;Zhao, Bing-Xin;Li, Jun-Yong;Huang, Xiao-Jun;Lin, Jing; Wang, Ying; Ye, Wen-Cai(*); Chen, Wei-Min(*). Regioselective and stereoselective photodimerization of securinine-type and norsecurinine-type alkaloids，Tetrahedron，2014，70（33）：4903-4909. 8. Wang, Fang; Sun, Jun-Rong; Huang, Mei-Yan; Wang, Hui-Ying; Sun, Ping-Hua; Lin, Jing; Chen, Wei-Min(*). Design, synthesis and anti-inflammatory evaluation of novel 5-benzylidene-3,4-dihalo-furan-2-one derivatives，European Journal of Medicinal Chemistry，2014，72：35-45. 9. Shan, Ling-Xing; Sun, Ping-Hua(*); Guo, Bao-Qin; Xu, Xing-Jun; Li, Zhi-Qiang; Sun, Jia-Zhi; Zhou,Shu-Feng; Chen, Wei-Min(*). Synthesis and antibacterial activities of acylide derivatives bearing an aryl-tetrazolyl chain，Drug Design, Development and Therapy，2014，8：1515-1525. 10. Zhao, Bing-Xin; Wang, Ying; Li, Chen; Wang, Guo-Cai; Huang, Xiao-Jun; Fan, Chun-Lin; Li, Qing-Ming; Zhu,Hua-Jie(*); Chen, Wei-Min(*); Ye, Wen-Cai(*). Flueggedine, a novel axisymmetric indolizidine alkaloid dimer from Flueggea virosa，Tetrahedron Letters，2013，54（35）：4708-4711. 11. Ruan, Zhi-Xiong; Huangfu, De-Sheng; Sun, Ping-Hua(*); Chen, Wei-Min(*). Molecular modeling studies on 3,4-dihydroquinazolines as trypanothione reductase inhibitors using 3D-QSAR and docking approaches，Medicinal Chemistry Research，2013，22（8）：3541-3555. 12. Jia, Fei; Hong, Juan; Sun, Ping-Hua; Chen, Jian-Xin; Chen, Wei-Min(*). Facile Synthesis of the Neuraminidase Inhibitor Peramivir，Synthetic Communications，2013，43（19）：2641-2647. 13. Liu, Junshan; Zhang, Dongmei; Li, Yuan; Chen, Weimin; Ruan, Zhixiong; Deng, Lijuan; Wang, Liwei; Tian,Haiyan; Yiu, Anita; Fan, Chunlin; Luo, Hai; Liu, Shanwen; Wang, Ying; Xiao, Gaokeng; Chen, Lixin; Ye,Wencai(*). Discovery of Bufadienolides as a Novel Class of ClC-3 Chloride Channel Activators with Antitumor Activities，Journal of Medicinal Chemistry，2013，56（14）：5734-5743. 14. Ruan, Zhi-Xiong; Huangfu, De-Sheng; Xu, Xing-Jun; Sun, Ping-Hua; Chen, Wei-Min(*). 3D-QSAR and molecular docking for the discovery of ketolide derivatives，Expert Opinion on Drug Discovery，2013，8（4）：427-444. 15. Zhang, Dong-Mei; Li, Ying-Jie; Shu, Chang; Ruan, Zhi-Xiong; Chen, Wei-Min; Yiu, Anita; Peng,Ying-Hui; Wang, Jiao; Lan, Ping; Yao, Zhe; Fung, Kwok-Pui; Fu, Li-Wu; Chen, Zhe-Sheng; Ye, Wen-Cai(*). Bipiperidinyl derivatives of 23-hydroxybetulinic acid reverse resistance of HepG2/ADM and MCF-7/ADR cells，Anti-Cancer Drugs，2013，24（5）：441-454. 16. Wang, Wen-Jing; Wang, Lei; Huang, Xiao-Jun; Jiang, Ren-Wang; Yang, Xiao-Lin; Zhang, Dong-Mei; Chen,Wei-Min; Tang, Ben-Qin; Wang, Ying; Zhang, Xiao-Qi; Ye, Wen-Cai(*).Two pairs of new benzofuran enantiomers with unusual skeletons from Eupatorium chinense，Tetrahedron Letters，2013，54（26）：3321-3324. 17. Li, Jun-Yong; Zhao, Bing-Xin; Zhang, Wen; Li, Chen; Huang, Xiao-Jun; Wang, Ying(*); Sun, Ping-Hua; Ye,Wen-Cai; Chen, Wei-Min(*). Unexpected ring contraction and oxidation rearrangement reactions of securinine，Tetrahedron，2012，68（21）：3972-3979. 18. Liu, Guo-Yong; Guo, Bao-Qin; Chen, Wan-Na; Cheng, Chao; Zhang, Qian-Lan; Dai, Mi-Bei; Sun,Jun-Rong; Sun, Ping-Hua(*); Chen, Wei-Min(*). Synthesis, Molecular Docking, and Biofilm Formation Inhibitory Activity of 5-Substituted 3,4-Dihalo-5H-furan-2-one Derivatives on Pseudomonas aeruginosa，Chemical Biology & Drug Design，2012，79（5）：628-638. 19. Lan, Ping，Wu, Zhi-Wei，Chen, Wan-Na，Sun, Ping-Hua，Chen, Wei-Min(*)，Molecular modeling studies on phosphonic acid-containing thiazole derivatives: design for fructose-1,6-bisphosphatase inhibitors，Journal of Molecular Modeling，2012，18（3）：973-990. 20. Zhang, Dong-Mei，Shu, Chang，Chen, Jun-Jiang，Sodani, Kamlesh，Wang, Jiao，Bhatnagar, Jaya，Lan,Ping，Ruan, Zhi-Xiong，Xiao, Zhi-Jie，Ambudkar, Suresh V.，Chen, Wei-Min，Chen, Zhe-Sheng，Ye, Wen-Cai(*)，BBA, a Derivative of 23-Hydroxybetulinic Acid, Potently Reverses ABCB1-Mediated Drug Resistance in Vitro and in Vivo，Molecular Pharmaceutics，2012，9（11）：3147-3159.

学术兼职

1. 广东省药学会药物化学专业委员会委员 2. European Journal of Medicinal Chemistry , Bioorganic & Medicinal Chemistry Letters, Chemical Biology & Drug Design，有机化学等国际国内学术期刊稿件评阅人。2015年被European Journal of Medicinal Chemistry授予Outstanding Reviewer; 2016年Bioorganic & Medicinal Chemistry Letters授予Recognized Reviewer。