个人简介
招生专业
070105-运筹学与控制论
招生方向
图论及其应用
生物信息学
教育背景
1985-09--1995-06 山东大学 本科/硕士/博士
工作简历
2005-04~现在, 中国科学院数学与系统科学研究院, 研究员
1999-01~2005-03,中国科学院数学与系统科学研究院, 副研究员
1997-03~1998-12,中国科学院应用数学所, 助理研究员
1995-07~1997-02,中国科学院应用数学所, 博士后
教授课程
组合数学
奖励信息
(1) 全国优秀科技工作者, 一等奖, 国家级, 2016
(2) 国务院政府特殊津贴, 一等奖, 国家级, 2013
专利成果
( 1 ) 一种药物增效组合预测方法及实验验证, 发明, 2014, 第 1 作者, 专利号: ZL 201110210508.0
科研项目
( 1 ) 随机复杂数据与随机复杂结构理论方法及其应用, 参与, 国家级, 2009-01--2013-12
( 2 ) 优化方法及其在信息技术中的应用, 主持, 部委级, 2009-01--2012-12
( 3 ) 图理论和算法研究及其在生物信息学中的应用, 主持, 国家级, 2017-01--2020-12
( 4 ) 复杂疾病相关的非编码RNA识别模型及算法研究, 主持, 国家级, 2013-01--2017-12
( 5 ) 协同药物研发中的关键数学问题, 主持, 国家级, 2013-01--2013-12
已指导学生
程郁琨 硕士研究生 070105-运筹学与控制论
肖岚 博士研究生 070105-运筹学与控制论
任伟 博士研究生 070105-运筹学与控制论
吴玉文 博士研究生 070105-运筹学与控制论
廖小平 博士研究生 070105-运筹学与控制论
王艺桥 博士研究生 070105-运筹学与控制论
陈兴 博士研究生 070105-运筹学与控制论
刘明熹 博士研究生 070105-运筹学与控制论
徐鑫 博士研究生 070105-运筹学与控制论
张瑶 博士研究生 070105-运筹学与控制论
唐与聪 博士研究生 070105-运筹学与控制论
曹鲁 博士研究生 070105-运筹学与控制论
现指导学生
张成芝 博士研究生 070105-运筹学与控制论
周乐为 博士研究生 070105-运筹学与控制论
王齐 硕士研究生 070105-运筹学与控制论
马驰骋 博士研究生 070105-运筹学与控制论
田雷霞 博士研究生 070105-运筹学与控制论
近期论文
查看导师新发文章
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(1) A novel approach based on KATZ measure to predict associations of human microbiota with non-infectious diseases, Bioinformatics, 33(5), 2017, 733–739, 2017, 第 4 作者
(2) HAMDA: Hybrid Approach for MiRNA-Disease Association prediction, Journal of Biomedical Informatics, 2017, 第 4 作者
(3) NRDTD: a database for clinically or experimentally supported non-coding RNAs and drug targets associations, Database, 2017, 1–6, 2017, 第 4 作者
(4) PBHMDA: Path-Based Human Microbe-Disease Association Prediction, frontiers in Microbiology, 2017, 第 5 作者
(5) PBMDA: A novel and effective path-based computational model for miRNA-disease association prediction, PLOS Computational Biology, 2017, 第 4 作者
(6) Prediction of microbe–disease association from the integration of neighbor and graph with collaborative recommendation model, Journal of Translational Medicine, 2017, 第 6 作者
(7) RKNNMDA: Ranking-based KNN for MiRNA-Disease Association prediction, RNA Biology, 2017, 第 3 作者
(8) A novel computational model based on superdisease and miRNA for potential miRNA–disease association prediction, Molecular BioSystems, 2017, 第 5 作者
(9) MCMDA: Matrix completion for MiRNA-disease association prediction, Oncotarget, 2017, 第 4 作者
(10) LRLSHMDA: Laplacian Regularized Least Squares for Human Microbe– Disease Association prediction, scientific reports, 2017, 第 6 作者
(11) NLLSS: Predicting Synergistic Drug Combinations Based on Semi-supervised Learning, PLoS Computational Biology, 2016, 通讯作者
(12) IRWRLDA: Improved random walk with restart for lncRNA-disease association prediction, Oncotarget, 2016, 第 3 作者
(13) Prediction of disease-related interactions between microRNAs and environmental factors based on a semi-supervised classifier, PLoS ONE, 2012, 通讯作者
(14) Minimum degree, edge-connectivity and radius, Journal of Combinatorial Optimization, 2012, 第 4 作者
(15) A Note on Semi-coloring of Graphs, Graphs and Combinatorics, 2012, 通讯作者
(16) Planar graphs with maximum degree 8 and without intersecting chordal 4-cycles are 9-totally colorable, Science in China, 2012, 通讯作者
(17) RWRMDA: predicting novel human microRNA-disease associations, Molecular BioSystems, 2012, 通讯作者
(18) Drug–target interaction prediction by random walk on the heterogeneous network, Molecular BioSystems, 2012, 通讯作者
(19) A novel disease genes prioritization method using module partition and rank fusion, OMICS: A Journal of Integrative Biology, 2010, 通讯作者
(20) Simple Probabilistic Algorithm for Detecting Community Structure in Social Networks, Phys. Rev. E, 2009, 通讯作者
(21) On potentially Kr+1 - U-graphical Sequences, UTILITAS MATHEMATICA, 2009, 通讯作者
(22) Graphs Isomorphic to Their Maximum Matching Graphs, Acta Mathematica Sinica, 2009, 通讯作者
(23) Induced Subgraph in Random Regular Graph, J. of Sys. Sci. and Complexity, 2008, 第 2 作者
(24) Factor-Critical Graphs with Given Number of Maximum Matchings, Graphs and Combinatorics, 2008, 通讯作者
(25) Linear Time Construction of 5-Phylogenetic Roots for Tree Chordal Graphs, Journal of Combinatorial Optimization, 2008, 通讯作者
(26) A Full-scale Solution to the Rectilinear Obstacle-Avoiding Steiner Problem, Elsevier INTEGRATION, the VLSI Journal, 2008, 通讯作者
(27) Detecting Community Structure by Network Vectorization, In Proceedings of The 14th International Computing and Combinatorics Conference, LNCS 5092, 2008, 第 2 作者
(28) l-OAT: l-Geometry Obstacle-Avoiding Tree Construction with O(nlogn) Complexity, IEEE Trans. on COMPUTER-AIDED DESIGN of Integrated Circuits and Systems, 2007, 通讯作者
(29) An O(nlogn) Algorithm for Obstacle-Avoiding Routing Tree Construction in the λ-Geometry Plane, In: Proceedings of ACM International Symposium on Physical Design (ISPD), 2006, 通讯作者
(30) DraXRouter: Global Routing in X-Architecture with Dynamic Resource Assignment, In: Proceedings of IEEE/ACM Asia and South Pacific Design Automation Conference (ASP-DAC), 2006, 通讯作者
(31) Strictly chordal graphs are leaf powers, Journal of Discrete Algorithms, 2006, 通讯作者
(32) ACO-Steiner: Ant Colony Optimization Based Rectilinear Steiner Minimal Tree Algorithm, Journal of Computer Science Technology, 2006, 通讯作者
(33) Via-Aware Global Routing for Good VLSI Manufacturability and High Yield, Proc.of IEEE 16th International Conference on Application-specific Systems, Architectures and Processors, 2005, 通讯作者
(34) A Routing Paradigm with Novel Resources Estimation and Routability Models for X-Architecture Based Physical Design, International Workshop on Embedded Computer Systems: Architectures, Modeling, and Simulation, Lecture Notes in Computer Science, 2005, 通讯作者
(35) The Polygonal Contraction heuristic for Rectilinear Steiner Tree Construction, Proceedings of IEEE/ACM ASP-DAC, 2005, 通讯作者
(36) An-OARSMan: Obstacle-Avoiding Routing Tree Construction with Good Length Performance, Proceedings of IEEE/ACM ASP-DAC, 2005, 通讯作者
(37) An Efficient Low-Degree RMST Algorithm for VLSI/ULSI Physical Design, Integrated Circuits and System Design, Springer Lecture Notes in Computer Science (LNCS), 2004, 通讯作者
(38) Path Decomposition of 3-regular Graphs, Journal of System Sciences and Mathematics Science, 2004, 第 1 作者
(39) Isolated Toughness and Fractional k-Covered Graphs, Acta Mathematicae Sinica, 2004, 第 2 作者
(40) The Structural Properties of Hexagonal Steiner Minimum Trees for Terminals on the Boundary of an Equilateral Triangle, Journal of Information and Computational Science , 2004, 通讯作者
(41) An Efficient Rectilinear Steiner Minimum Tree Algorithm Based on Ant Colony Optimization, Proceedings of IEEE ICCCAS, 2004, 通讯作者
(42) Some result on the Graphic Isolated Toughness and Fractional Factor, Acta Mathematicae Sinica, 2004, 第 2 作者
(43) Isolated Toughness and Fractional k-Deleted Graphs, OR Transactions, 2003, 第 2 作者
(44) On Fractional (g,f)-deleted Graphs, Mathematica Applicata, 2003, 第 2 作者
(45) On Fractional (g,f)-Covered Graphs, OR Transactions, 2002, 通讯作者
(46) The Cycle Structure of Hypergraphs, Chinese Science Bulletin, 2001, 第 1 作者
(47) Linear Vertex Arboricity, Independence Number and Clique Cover Number, Ars Combinatoria, 2001, 通讯作者
(48) An Application of Hypergraph on the Generalized Gossip Problem, the proceedings of the sixth National Conference of Operations Research Society of China, 2001, 通讯作者
(49) Decomposition Graphs into (g,f)-Factors, Graphs and Combinatorics, 2000, 第 1 作者
(50) A New Result on Alspach’s Problem, Graphs and Combinatorics, 1999, 第 1 作者
(51) On the Optimal Four-Way Switch Box Routing Structures of FPGA Gready Routing Architectures, Integration, The VLSI Journal, 1998, 通讯作者
(52) Orthogonal (g,f)-Factorization in Bipartite Graph, Hokkaido Math. Journal, 1998, 第 1 作者
(53) The Existence of Subgraph with Orthogonal (g,f)- Factorization, Science in China (English Version), 1998, 第 1 作者
(54) The Steiner Tree problem with orientation Metrics, J.of Computer System Sciences, 1997, 第 1 作者
(55) (g,f)-Factorizations of Graphs Orthogonal to [1, 2]-Subgraph, Acta Mathematicae Applicatae Sinica, 1997, 第 1 作者
(56) Orthogonal [k-1,k+1]-factorizations in graphs, J. Statistical Planning and Inference, 1996, 第 2 作者
(57) New Results on (g,f)-Factorizations of Graphs, Mathematica Applicata, 1996, 第 1 作者
(58) Some New Result on (g,f)-Factorizations of Graphs, Journal of Combinatorial Mathematics and Combinatorial Computing, 1995, 第 1 作者
(59) (g,f)-Factorizations of Graphs, Journal of System Sciences and Mathematics Science, 1995, 第 1 作者
(60) (g,f)-factors with given properties, Journal of Shandong University, 1995, 第 1 作者
(61) The Existence of k-fator and the Condition of Neighbourhood Union, Pure Applied Mathematics, 1994, 第 1 作者
(62) Some Theorems on (g,f)-Factorizations of Graphs, Combinatorics, Graph Theory, Algorithms and Applications, 1994, 第 1 作者
(63) on (g,f)-Factorizations of Graphs, Journal of Shandong University, 1993, 第 1 作者