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个人简介

授課領域 分子生物學、分子毒理學 校內榮譽一覽 99 資深優良教師 國立清華大學 學歷一覽 康乃爾大學 美國 博士

研究领域

分子生物學、分子毒理學

近期论文

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2013 2013,Lin, C.-Y., Liu, Y.-C., Lin, M.-C., Nguyen, T., Tam,, M.F., Chein, C.-Y., Lin, M.-T. and Lin, L.-Y.* (2012) Expression and characterization of SUMO-conjugated metal-responsive transcription factor 1: SUMO-interacting motif-dependent cross-interaction and distinct DNA binding activity. J. Biochem. (in press), 林立元 2013 2013,Fang, S.L., Fan, T.-C., Fu, H.-W., Chen, C.-J., Hwang, C.-H., Hung, T.-J., Lin, L.-Y. and Chang, M. D.-T. (2013) A novel cell-penetrating peptide derived from human eosinophil cationic protein. PLoS ONE (in press), 林立元 2012 2013,Chao, C.-H., Chang, Y.-F., Chen, H.-C., Lin, L.-Y., Yu, P.-C., Chang, Y.-S., Lee, Y.-J. and Chou, C. (2012) Detection of urine cofilin-1 from patients hospitalized in the intensive care unit using the metal-enhanced fluorescence technique. Sensor Actuat. B-Chem. 173:184-190, 林立元 2012 2013,Chao, C.-H., Wu, C.-S., Huang, C.-C., Liang J.-C., Wang, H.-T., Tang, P.-T., Lin, L.-Y.* and Ko, F.-H.* (2012) A rapid and portable sensor based on protein-modified gold nanoparticle probes and lateral flow assay for naked eye detection of mercury ion. Microelecton. Eng. 97:294-296, 林立元 2012 2013,Lin, M.-C., Liu, Y.-C., Tam, M.F., Lu, Yu-Ju, Hsieh, Y.-T., and Lin, L.-Y.* (2012) PTEN interacts with metal-responsive transcription factor 1 and stimulates its transcriptional activity. Biochem. J. 441:367-377, 林立元 2011 2011,Ma, Y.-H., Huang, C.-P., Tsai, J.-S., Shen, M.-Y., Li, Y.-K. and Lin, L.-Y.* (2011) Water-soluble germanium nanoparticles cause necrotic cell death and the damage can be attenuated by blocking the transduction of necrotic signaling pathway Toxicol. Lett. 207:258-269, 林立元 2011 2011,Liu, Y.-C., Lin, M.-J., Chen, H.-C., Tam, M.F. and Lin, L.-Y.* (2011) The role of small ubiquitin-like modifier-interacting motif in the assembly and regulation of metal-responsive transcriptional factor 1. J. Biol. Chem. 286:42818-42829, 林立元 2009 2011,Hsu, T.-S., Yang, P.-M. and Lin, L.-Y.* (2009) Attenuation of cadmium-induced necrotic cell death by necrostatin-1: Potential necrostatin-1 acting sites. Toxicol. Appl. Pharmacol. 235: 153-162, 林立元 2009 2009,Lin, M.H., Hsu, T.-S., Yang,, P.-M., Tsai, M.-Y., Perng, T.-P. and Lin, L.-Y.* (2009) Comparison of organic and inorganic germanium compounds in cellular radiosensitivity and preparation of germanium nanoparticles as a radiosensitizer. Int. J. Radiat. Biol. (85:214-226), 林立元 2007 2007,Yang, P.-M., Chen, H.-C., Tsai, J.-S. and Lin, L.-Y.* (2007) Cadmium induces Ca2+-dependent necrotic cell death through calpain-triggerd mitochondrial depolarization and ROS-mediated inhibition of NF-κB activity. Chem. Res. Toxicol. 20:406-415, 林立元 2005 2005,Lin, K.-A., Chen, J.-H., Lee, D.-F. and Lin, L.-Y. (2005) Alkaline induces metallothionein gene expression and potentiates cell proliferation in Chinese hamster ovary cells. J. Cell. Physiol. 205:428-436, 林立元 2005 2005,Yang, P.-M., Chiu, S.-J. and Lin, L.-Y. (2005) Differential effects of salen and manganese-salen complex (EUK-8) on the regulation of cellular cadmium uptake and toxicity. Toxicol. Sci. 85:551-559, 林立元 2005 2005,Wu, C.-M and Lin, L.-Y. (2005) Utilization of albumin-based sensor chips for the detection of metal content and characterization of metal-protein interaction by surface plasmon resonance. Sensors and Actuators B: Chemical 110:231-238, 林立元 2004 2004,Wu, C.-M and Lin, L.-Y. (2004) Immobilization of metallothionein as a sensitive biosensor chip for the detection of metal ions by surface plasmon resonance. Biosens. Bioelectron. 20:864-871, 林立元 2004 2004,Yang, P.-M., Chiu, S.-J., Lin, K.-A. and Lin, L.-Y. (2004) Effect of Cadmium on Cell Cycle Progression in Chinese Hamster Ovary Cells. Chemico-Biol. Interact. 149:125-136, 林立元 2003 2003,Chiu, S.-J., Lee, M.-Y., Chou, W.-G. and Lin, L.-Y. (2003) Germanium Oxide Enhances Radiosensitivity of Cells. Radia. Res. 159:391-400, 林立元 2003 2003,Sheu, W. H.-H., Chen, Y.T., Lee, W.-J., Wang, C.-W. and Lin, L.Y. (2003) A relationship between serum ferritin and the insulin resistance syndrome is present in non-diabetic women but not in non-diabetic men. Clin. Endocrinol. 58:380-385, 林立元

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