个人简介
教育经历 & 研究经历
2003.9-2006.7:华东师范大学生命科学学院,脑功能基因组学教育部(上海市)重点实验室 博士
2012.3-2013.9:Massachusetts Institute of Techonology(MIT), 大脑与认知科学系, Mcgovern大脑研究所 博士后
工作经历
2006.07-2013.11 华东师范大学 脑功能基因组学研究所 助理研究员
2013.12-至今 华东师范大学 心理与认知科学学院 助理研究员、副研究员、副教授
研究领域
精神疾病中异常行为发生的神经机制
记忆再巩固及认知灵活性的分子和环路机制
阿尔兹海默病记忆障碍的调控机制
近期论文
查看导师新发文章
(温馨提示:请注意重名现象,建议点开原文通过作者单位确认)
Tianhua Wang, Yunxia Bai, Xianjie Zheng, Xinxia Liu, Shuang Xing, Linbin Wang, Huimin Wang, Guoping Feng*, Chunxia Li*. Sapap4 deficiency leads to postsynaptic defects and abnormal behaviors relevant to hyperkinetic neuropsychiatric disorder in mice. Cerebral Cortex. 2023. 33(4):1104-1118.
Yunxia Bai, Huimin Wang, Chunxia Li*. SAPAP Scaffold proteins: from synaptic function to neuropsychiatric disorders. Cells. 2022. 11, 3815. https://doi.org/10.3390/cells11233815.
Wenjun Peng, Yuan Xie, Chongzheng Liao, Yunxia Bai, Huimin Wang*, Chunxia Li*. Spatiotemporal patterns of gliosis and neuroinflammation in presenilin 1/2 conditional double knockout mice. Frontiers in aging neuroscience. 2022. online published. doi: 10.3389/fnagi.2022.966153/full.
Ting Cao, Xiaojuan Zhou, Xianjie Zheng, Yue Cui, Joe Z Tsien, Chunxia Li*, Huimin Wang*. Histone deacetylase inhibitor alleviates the neurodegenerative phenotypes and histone dysregulation in presenilins-deficient mice.Frontier in Aging Neuroscience. 2018;10:137. doi: 10.3389/fnagi.2018.00137. eCollection 2018.
Beijun Wu, Chunxia Li, Huimeng Lei. SAPAP4 Deletion Causes Synaptic Dysfunction in the nucleus accumbens. Biochemical and Biophysical Research Communications. Biochemical and Biophysical Research Communications. 2018 Oct 12. pii: S0006-291X(18)32158-2. doi: 10.1016/j.bbrc.2018.10.016.
Chunxia Li, Ning Zhang, Yinghe Hu, Huimin Wang. NR2B overexpression leads to the enhancement of specific protein phosphorylation in the brain. Brain Research. 2014. Aug 13. Pii:S0006-8993(14)01069-5. Doi: 10.1016/j.brainres.2014.08.005.
Chunxia Li, Men Su, Huimin Wang, Yinghe Hu. Global view of transcriptome in the brains of aged NR2B transgenic mice. Neural Regeneration Research. 2013.Volume 8, Number 29 2734-2743.
Suzhen Dong1,Qingwen Zeng1, E.Siobhan Mitchell, Jin Xiu, Yale Duan1, Chunxia Li1, Jyoti K. Tiwari, Yinghe Hu, Xiaohua Cao, Zheng Zhao. Curcumin Enhances Neurogenesis and Cognition in Aged Rats: Implications for Transcriptional Interactions Related to Growth and Synaptic Plasticity.PloS One. 2012;7(2):e31211. doi: 10.1371/journal.pone.0031211. Epub 2012 Feb 16(1并列第一作者)
Chunxia Li, Suzhen Dong, Huimin Wang, Yinghe Hu. Microarray analysis of gene expression changes in the brains of NR2B-induced memory-enhanced mice. Neuroscience. 2011, 197: 121-131
Chunxia Li, Wenze Niu, Cecilia H. Jiang, Yinghe Hu. Effects of enriched environment on gene expression and signal pathways in cortex of hippocampal CA1 specific NMDAR1 knockout mice. Brain Research Bulletin 71 (2007) 568–577.
Bing Mei1, Chunxia Li1, Suzhen Dong1, Cecilia H. Jiang, Huimin Wang, Yinghe Hu. Distinct gene expression profiles in hippocampus and amygdala after fear conditioning. Brain Research Bulletin 67:1–12, 2005. (1并列第一作者)
Suzhen Dong, Chunxia Li, Pu Wu, Joe Z. Tsien, Yinghe Hu. Environment enrichment rescues the neurodegenerative phenotype in Presenilin-deficient mice. European Journal of Neuroscience 2007. 26(1):101-112, 2007.
Liyan Fang, Mancang Zhang, Chunxia Li, Suzhen Dong, Yinghe Hu. Chemical Genetic Analysis Reveals the Effects of NMU2R on the Expression of Peptide Hormones. Neuroscience Letters. 404:148–153, 2006.
张宁,李春霞*.前脑特异性过表达NR2B基因对小鼠社会交往能力的影响华东师范大学学报(自然科学版) 2012, 4:75-82
李世佳,徐敏华,李春霞,周天舒,孟博,梅兵. 前脑特异性过表达NR2B基因对小鼠焦虑样行为无明显影响。生理学报。2009, 61 (3): 272-278
学术兼职
专业协会:
美国神经科学学会会员
中国神经科学学会会员
中国生理学会会员
中国神经科学学会学习记忆基础与临床分会会员
上海神经科学学会会员
上海市心理学会会员
期刊特约评审:
Cerebral Cortex、Neurobiology of learning and memory、Neuropharmcology、
Journal of Neuroinflammation、Molecular Neurobiology、Cellular and molecular life sciences、
ACS Chemical Neuroscience、Neural Regeneration Research