Cheng, Jianjun - University of Illinois at Urbana-Champaign - Department of Materials Science and Engineering

个人简介

Education 2001 Ph.D., Materials Science, University of California, Santa Barbara 1996 M.S., Chemistry, Southern Illinois University at Carbondale 1993 B.S., Chemistry, Nankai University, China Professional Employment 2016 - present Hans Thurnauer Professor, Department of Materials Science and Engineering 2015 - 2016 Professor, Department of Materials Science and Engineering, UIUC 2011 Sept-Dec. Visiting Professor, University of Chicago 2011-2015 Associate Professor, Department of Materials Science and Engineering, UIUC 2005-2011 Assistant Professor, Department of Materials Science and Engineering, UIUC 2011-present Faculty Affiliate of Materials Research Laboratory 2010-present Faculty Affiliate of Beckman Institute for Advanced Science and Technology 2010-present Faculty Affiliate of Institute of Genomic Biology 2009-present Faculty Affiliate of Department of Chemistry 2009-present University of Illinois Cancer Center Full Member 2005-present Micro and Nanotechnology Laboratory 2005-present Department of Bioengineering 2004-2005 Postdoctoral Scientist, Chemical Engineering, Massachusetts Institute of Technology 2001-2004 Senior Scientist, Insert Therapeutics, Inc 1996-2001 Research Assistant, University of California, Santa Barbara 1993-1996 Teaching and Research Assistant, Southern Illinois University Awards 2015 Faculty Entrepreneurial Fellow, UIUC 2015 Distinguished Promotion Award, UIUC 2015 Fellow, American Institute for Medical and Biological Engineering (AIMBE) 2015 Fellow, American Chemical Society-Division of Polymer Chemistry (ACS-POLY) 2014 Associate, Center for Advanced Study, UIUC 2013 Willett Faculty Scholar Award 2011 Tau Beta Pi Eminent Engineer 2010 NIH Director's New Innovator Award 2010 Xerox Award for Faculty Research, UIUC 2008,2009,2010 Teacher Ranked as Excellent, UIUC Center for Teaching Excellence (5 times) 2008 National Science Foundation CAREER Award 2007 Prostate Cancer Foundation Competitive Award Professional Activities 2013 Symposium chair, American Chemical Society National Meeting, Indianapolis, IN 2012-present Associate Editor, Biomaterials Science, Royal Society of Chemistry 2011-present Editorial Board Member, Journal of Molecular Biomarkers & Diagnosis 2010 Invitee, Golden Triangle Workshop, President's Innovation And Technology Advisory Committee (PITAC), Washington DC 2011 Symposium Chair, Institute of Electrical and Electronics Engineers and the Engineering in Medicine and Biology Society (IEEE-EMBS) in Boston, MA 2010 Symposium Chair: POLY, American Chemical Society National Meeting, San Francisco, CA 2008 Symposium Chair: Materials Research Society National Meeting, San Francisco, CA 2007 Symposium Chair: PMSE, American Chemical Society National Meeting, Boston, MA

研究领域

(1) Polymer biomaterials, in particular functional polypeptides and polyesters (2) Polymer and materials chemistry (3) Nanomedicines for drug/gene delivery, imaging and diagnosis (4) Controlled release systems: design and application (5) Functional materials, smart materials and molecular probes

近期论文

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Yin, Q.; Tang, L.; Cai, K.; Tong, R.; Sternberg, R.; Yang, X.; Dobrucki, L.W.; Borst, L.B.; Kamstock, D.; Song, Z.; Helferich, W.G.; Cheng, J.; Fan, T.M. "Pamidronate Functionalized Nanoconjugates for Targeted Therapy of Focal Skeletal Malignant Osteolysis", PNAS, 2016, 113, E4601-4609. (1DP2OD007246, NSF-DMR 1309525; PMC4987772) Wang, R.; Zhang, J.; Yin, Q.; Xu, Y.; Cheng, J.; Tong, R. "Controlled Ring-Opening Polymerization of O-Carboxyanhydrides Using β-Diiminate Zinc Catalyst", Angew. Chem. Int. Ed., 2016, 55, 13010-13014. (NSF-CHE-1308485) Wang, H.; Gauthier, M.; Kelly, J. R.; Miller, R.J.; Xu, M.; O'Brien, W.D.; Cheng, J. "Targeted Ultrasound Assisted Cancer-Selective Chemical Labeling and Subsequent Cancer Imaging via Click Chemistry", Angew. Chem. Int. Ed., 2016, 55, 5452-5456. (1DP2OD007246, NSF-DMR 1309525; PMC4918225) Wang, J.; Yuan, L.; Wang, Z.; Rahman, Md A.; Huang, Y.; Zhu, T.; Wang, R.; Cheng, J.; Wang, C.; Chu, F.; Tang, C. "Photoinduced Metal-Free Atom Transfer Radical Polymerization of Biomass Based Monomers", Macromolecules, 2016, 49, 7709-7717. Zheng, N.; Liu, Y.; Cheng, J. “Gene Delivery Method Using Photo-Responsive Poly(b-Amino Ester)”, Non-Viral Gene Delivery Vectors, edited by Candiani, G., Humana Press, 2016, 259-267. Yin, L.; Zheng, N., Cheng, J. “Highly Efficient siRNA Delivery Mediated by Cationic Helical Polypeptides and Polypeptide-Based Nanosystems”, siRNA Delivery Methods, edited by Shum, K. and Rossi, J., Humana Press, 2016, 37-47. Baumgartner, R.; Ryba, K.; Song,Z.; Wang, R.; Harris, K.; Katzd, J.S.; Cheng, J."A delayed curing ROMP based thermosetting resin", Polymer Chemistry, 2016, 7, 5093-5098. (Dow Chemical Company) Xing, H.; Xu, W.; Hwang, K.; Wu, P.; Yin, Q.; Li, Z.; Cheng, J.; Lu, Y. "The Effects of Spacer Length and Composition on Aptamer-Mediated Cell-Specific Targeting with Nanoscale PEGylated Liposomal Doxorubicin", CHEMBIOCHEM, 2016, 17, 1111-1117. Wang H.; Tang L.; Liu Y.; Dobrucka I.T.; Dobrucki L.W.; Yin L.; Cheng J. "In Vivo Targeting of Metabolically Labeled Cancers with Ultra-Small Silica Nanoconjugates", Theranostics 2016, 6, 1467-1476. (PMC4924513) Song, Z.; Huang, Y.; Prasad, V.; Baumgartner, R.; Zhang, S.; Harris, K.; Katz, J.S.; Cheng, J. "Preparation of Surfactant-Resistant Polymersomes with Ultrathick Membranes through RAFT Dispersion Polymerization", ACS Applied Materials & Interfaces, 2016, 8, 17033-17037. (Dow Chemical Company) Bai, Y.; Nguyen, L.T.; Song, Z.; Peng, S.; Lee, J.; Zheng, N.; Kapoor, I.; Lauren D. Hagler, L.; Cai, K.; Cheng, J.; Chan, H.Y.; Zimmerman, S.C. "Integrating Display and Delivery Functionality with a Cell Penetrating Peptide Mimic as a Scaffold for Intracellular Multivalent Multi-targeting", J. Am. Chem. Soc., 2016, 138, 9498-9507. Zhang, Y.; Ying, H. (co-first author); Hart, K.R.; Wu, Y.; Hsu, A.J.; Coppola, A.M.; Kim, T.A.; Yang, K.; Sottos, N.R.; White, S.R.; Cheng, J. "Malleable and Recyclable Poly(urea-urethane) Thermoset Bearing Hindered Urea Bonds", Advanced Materials, 2016, 28, 7646-7651. (CHE 1508710) Azzi, J.; Yin, Q.; Uehara, M.; Ohori, S.; Tang, L.; Cai, K; Ichimura, T.; McGrath, M.; Maarouf, M.; Kefaloyianni, E.; Loughhead, S.; Petr, J.; Sun, Q.; Kwon, M.; Tullius, M.; Andrian, U.; Cheng, J.; Abdi, R. "Targeted delivery of immunomodulators to lymph nodes", Cell Reports, 2016, 15, 1202-1213. (1DP2OD007246-01, NSF-CHE 1308485; PMC4973867) Ying, H.; Cheng, J. “One-step Construction of Aminosquaraine Backbone”, Dyes and pigments, 2016, 131, 264-267. (CHE 1508710) He, H.; Zheng, N.; Song, Z.; Kim, K.H.; Yao, C.; Zhang, R.; Zhang, C.; Huang, Y.; Uckun, F.M.; Cheng, J.; Zhang, Y.; Yin, L. "Suppression of Hepatic Inflammation via Systemic siRNA Delivery by Membrane-Disruptive and Endosomolytic Helical Polypeptide Hybrid Nanoparticles", ACS NANO, 2016, 10, 1859-1870. (CHE 1508710) Li, Y.; Bai, Y.; Zheng, N.; Liu, Y.; Vincil, G.A.; Pedretti, B.J.; Cheng, J.; Zimmerman, S. "Crosslinked Dendronized Polyols as a General Approach to Brighter and More Stable Fluorophores", Chemical Communications, 2016, 52, 3781-3784. Yen, J. ; Ying, H.; Wang, H.; Yin, L; Uckun, F.; Cheng, J. "CD44 Mediated Non-Viral Gene Delivery into Human Embryonic Stem Cells via Hyaluronic Acid Coated Nanoparticles", ACS Biomaterials Science & Engineering, 2016, 2, 326-335. (1DP2OD007246, 1R21EB013379, CHE-1153122) [COVER] Kang, S.; Murphy, R.; Hwang, S.; Lee, S.; Harburg, D.; Krueger, N.; Shin, J.; Gamble, P.; Cheng,H.; Yu, S.; Liu, Z.; McCall, J.; Stephen, M.; Ying, H.; Kim, J.; Park, G.; Webb, R.; Lee, C.; Chung, S.; Wie, D.; Gujar, A.; Cheng, J.; Huang, Y.; Lee, S.; Braun, P.; Ray, W.; Rogers, J.A. " Bioresorbable Silicon Electronic Sensors for the Brain", Nature, 530, 71-76. Xiong, M.; Lee, M.W.; Mansbach, R.A.; Song, Z.; Bao, Y; Jr. Peek, R. M.; Yao, C; Chen, Lin-Feng; Ferguson, A.L.; Wong, G.C.L.; Cheng, J. "Helical Antimicrobial Polypeptides with Radial Amphiphilicity", PNAS, 2015, 112, 13155-13160. (1DP2OD007246, 1R21EB013379, R21AI117080, CHE-1153122; PMC4629321) Cai, K.; He, X.; Song, Z.; Yin, Q.; Zhang, Y.; Uckun, F.M.; Jiang, C.; Cheng, J. "Dimeric Drug Polymeric Nanoparticles with Exceptionally High Drug Loading and Quantitative Loading Efficiency", J. Am. Chem. Soc., 2015, 137, 3458-3461. (1DP2OD007246-01, 1R21CA152627, DMR 07-48834, NSF-DMR 1309525) Tang, L.; Yin, Q.; Xu, Y.; Zhou, Q.; Cai, K.; Yen, J.; Dobrucki, L.W.; Cheng, J. "Bioorthogonal Oxime Ligation Mediated in Vivo Cancer Targeting", Chemical Science, 2015, 6, 2182-2186. (1DP2OD007246-01, DMR 07-48834; PMC4486360, NIHMS661301) Wu, X.; He, C.; Wu, Y.; Chen, X.; Cheng, J. "Nanogel-Incorporated Physical and Chemical Hybrid Gels for Highly Effective Chemo-Protein Combination Therapy", Advanced Functional Materials, 2015, 25, 6744-6755. Priftis, D.; Leon, L.; Song, Z.; Perry, S.L.; Margossian, K.O.; Tropnikova, A.; Cheng, J.; Tirrell M. "Self-Assembly of Alpha-Helical Polypeptides Driven by Complex Coacervation", Angew. Chem. Int. Ed., 2015, 54, 11128-11132. (NSF-CHE1153122) Gauthier, M.; Yin, Q.; Cheng, J.; O'Brien W.D. "Design of Albumin-Coated Microbubbles Loaded With Polylactide Nanoparticles", J Ultrasound Med, 2015, 34, 1363-1372. (1DP2OD007246-01; PMC4536807,NIHMS712338) Lee, J.S.; Deng, X.; Han, P.; Cheng, J. "Dual Stimuli-Responsive Poly(beta-amino ester) Nanoparticles for On-Demand Burst Release", Macromolecular Bioscience, 2015, 15, 1314-1322. (1DP2OD007246-01) Yin, Q.; Yin, L.; Wang, H.; Cheng, J. "Synthesis and biomedical applications of functional poly(alpha-hydroxy acids) via ring-opening polymerization of O-carboxyanhydrides", Accounts of Chemical Research, 2015, 48, 1777-1787. (1DP2OD007246-01) Uckun, F.M.; Mitchell, L.G.; Qazi, S.; Myers, D.E.; Ma, H.; Zheng, N.; Song, Z.; Liu, Y.; Cheng, J. "Development of Polypeptide-Based Nanoparticles for Non-Viral Delivery of CD22 RNA Trans-splicing Molecule as a New Precision Medicine Candidate Against B-lineage ALL", EBioMedicine, 2015, 2, 649-659. (1DP2OD007246-01, NSF-CHE 1308485; PMC4534679) Song, Z.; Kim, H.; Ba, X.; Baumgartner, R.; Lee, J.; Tang, H.; Leal, C.; Cheng, J. "Polypeptide Vesicles with Densely Packed Multilayer Membranes", Soft Matter, 2015, 11, 4091-4098. (Dow Chemical Company, NSF-CHE 1308485) Uckun, F.M.; Qazi, S.; Cheng, J.; Myers, D.E. "Liposomal Nanoparticles of a Spleen Tyrosine Kinase P-site Inhibitor Amplify the Potency of Low Dose Total Body Irradiation Against Aggressive B-precursor Leukemia and Yield Superior Survival Outcomes in Mice EBioMedicine", EBioMedicine, 2015, 2, 554-562. (1DP2OD007246-01; PMC4535154) Torabi, S.F.; Wu, P.; McGhee, C.E.; Chen, L.; Hwang, K.; Zheng, N.; Cheng, J.; Lu, Y. "In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing", PNAS, 2015, 112, 5903-5908. (PMC4434688) Tang, L.; Tong, R.; Coyle, V.J.; Yin, Q.; Pondenis, H.; Borst, L.B.; Cheng, J.; Fan, T.M. "Targeting Tumor Vasculature with Aptamer Functionalized Doxorubicin-Polylactide Nanoconjugates for Enhanced Cancer Therapy", ACS Nano, 2015, 9, 5072-5081. . Uckun, F.M.; Qazi, S.; Cheng, J. "Targeting leukemic stem cells with multifunctional bioactive polypeptide nanoparticles", Future Oncology, 2015, 11, 1149-1152. (1DP2OD007246-01) Baumgartner, R.; Song, Z.; Zhang, Y.; Cheng, J. "Functional Polyesters Derived from Alternating Copolymerization of Norbornene Anhydride and Epoxides", Polymer Chemistry, 2015, 6, 3586-3590. (Dow Chemical Compay) Zhang, Y.; Yin, Q.; Yen, J.; Li, J.; Ying, H.; Wang, H.; Hua, Y.; Chaney, E.; Boppart, S.; Cheng, J. "Non-Invasive, Real-Time Reporting Drug Release In Vitro and In Vivo", Chemical Communications, 2015, 51, 6948-6951. (1DP2OD007246-01; PMC4486253, NIHMS674723) Andrade, B.; Song, Z.; Li, J.; Zimmerman, S.; Cheng, J.; Moore, J.S.; Harris, K.; Katz, J. "New Frontiers for Encapsulation in the Chemical Industry", ACS Applied Materials & Interfaces, 2015, 7, 6359-6368. (Dow Chemical Company) Wang, H.C.; Zhang, Y.; Possanza, C.; Zimmerman, S.; Cheng, J.; Moore, J.; Harris, K.; Katz, J. " Trigger Chemistries for Better Industrial Formulations", ACS Applied Materials & Interfaces, 2015, 7, 6369-6382. (Dow Chemical Company) Wang, H.; Xu, M.; Xiong, M.H.; Cheng, J. " Reduction-Responsive Dithiomaleimide-Based Nanomedicine with High Drug Loading and FRET-Indicated Drug Release ", Chemical Communications, 2015, 51, 4807-4810. (NSF-DMR 1309525, 1DP2OD007246-01; NIHMS666739) Zheng, N.; Song, Z.; Liu, Y.; Zhang, R.; Zhang, R.; Yao, C.; Uckun, F.M.; Yin, L.; Cheng, J. "Redox-responsive, reversibly-crosslinked thiolated cationic helical polypeptides for efficient siRNA encapsulation and delivery", J. Controlled Release, 2015, 205, 231-239. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01) Uckun, F.M.; Ma, H.; Cheng, J.; Myers, D.E.; Qazi, S. "CD22deltaE12 as a molecular target for RNAi therapy", British Journal of Haematology, 2015, 169, 401-414. (1DP2OD007246-01) Cai, K.; Yen, J.; Yin, Q.; Liu, Y.; Song, Z.; Lezmi, S.; Zhang, Y.; Yang, X.; Helferich, W.G.; Cheng, J. "Redox-Responsive Self-Assembled Chain-Shattering Polymeric Therapeutics", Biomaterials Science, 2015, 3, 1061-1065. (DMR 07-48834, NSF-DMR 1309525, 1DP2OD007246-01, 1R21CA152627; NIHMS664361) Yin, L.; Chen, Y.; Zhang, Z.; Yin, Q.; Zheng, N.; Cheng, J. "Biodegradable Micelles Capable of Mannose-Mediated Targeted Drug Delivery to Cancer Cells", Macromolecular Rapid Communications, 2015, 36, 483-489. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; NIHMS683282) Ma, L.; Baumgartner, R.; Zhang, Y.; Song, Z.; Cai, K.; Cheng, J. "UV-Responsive Degradable Polymers Derived from 1-(4-Aminophenyl) ethane-1, 2-diol", Journal of Polymer Science, Part A, 2015, 53, 1161-1168. (Dow Chemical Company) [Cover] Zhang, R.; Song, Z.; Yin, L.; Lu, H.; Gabrielson, N.P.; Cheng, J. "Ionic α-Helical Polypeptides towards Non-Viral Gene Delivery" WIREs Nanomedicine & Nanobiotechnolog, 2015, 7, 98-110. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; NIHMS631933) Qu, Q.; Dong, L.; Louis, K.R.; Li, X.; Yang, H.; Sun, Q.; Crandall, S.R.; Tsang, S.; Zhou, J.; Cox, C.L.; Cheng, J.; Wang, F. "High-efficiency motor neuron differentiation from human pluripotent stem cells and the function of Islet-1", Nature Communications, 2014, 5, 3449. Ying, H.; Zhang, Y.; Cheng, J. "Dynamic urea bond for the design of reversible and self-healing polymers", Nature Communications, 2014, 5, 3218. (NSF-CHE 1153122, 1DP2OD007246-01; NIHMS554614) Tang, L.; Yang, X.; Yin, Q.; Cai, K.; Wang, H.; Chaudhury, I.; Yao, C.;Zhou, Q.; Kwon, M.; Hartman, J.A.; Dobrucki, I.T.; Dobrucki, L.W.; Borst, L.B.; Lezmi, S.; Helferich, W.G.; Ferguson, A.L.; Fan, T.M.; Cheng, J. "Investigating the optimal size of anticancer nanomedicine", PNAS, 2014, 111, 15344-15349. (1DP2OD007246-01, 1R21CA152627; PMC4217425) Ying, H.; Cheng, J. "Hydrolysable Polyureas Bearing Hindered Urea Bonds", J. Am. Chem. Soc., 2014, 136, 16974-16977. (NSF-CHE 1153122, 1DP2OD007246-01) Uckun, F.M.; Qazi, S.; Ma, H.; Yin, L.; Cheng, J. "A rationally designed nanoparticle for RNA interference therapy in B-lineage lymphoid malignancies", EBioMedicine, 2014, 1, 141-155. (1DP2OD007246-01; PMC4292938, NIHMS644169) Yin, L.; Huang, X.; Xu, H.; Zhang, Y.; Lam, J.; Cheng, J.; Rogers, JA. "Materials, Designs, and Operational Characteristics for Fully Biodegradable Primary Batteries", Advanced Materials, 2014, 26, 3879-3884. Yen, J.; Yin, L.; Cheng, J. "Enhanced Non-Viral Gene Delivery to Human Embryonic Stem Cells via Small Molecule-Mediated Transient Alteration of Cell Structure", Journal of Materials Chemistry B, 2014, 2, 8098-8105. (1DP2OD007246-01, 1R21EB013379-01, NSF-CHE 1153122; NIHMS632808) Zheng, C.; Niu, L.; Pan, W.; Zhou, J.; Lv, H.; Cheng, J.; Liang, D.; "Long-term kinetics of DNA interacting with polycations", Polymer, 2014, 55, 2464-2471. Myers, D.E.; Yiv, S.; Qazi, S.; Ma, H.; Cely, I.; Shahidzadeh, A.; Arellano, M.; Finestone, E.; Gaynon, P.; Termuhlen, A.; Cheng, J.; Uckun, F.,"CD19-antigen Q1 specific nanoscale liposomal formulation of a SYK Q2 P-site inhibitor causes apoptotic destruction of human B-precursor leukemia cells", Integrative Biology, 2014, 6, 766-780. (1DP2OD007246-01) Mahsan, K.; Chaudhury, I.; Cheng, J.; Safari, M.; Sadeghi, R.; Habibi-Rezaei, M.; Kokini, J.; "Immobilization of endo-inulinase on non-porous aminofunctionalized silica nanoparticles", Journal of Molecular Catalysis B: Enzymatic, 2014, 104, 48-55. Deng, X.; Zheng, N.; Song, Z.; Yin, L.; Cheng, J. "Trigger-responsive, fast-degradable poly(¦Â-amino ester)s for enhanced DNA unpackaging and reduced toxicity", Biomaterials, 2014, 35, 5006-5015. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; NIHMS574051) Song, Z.; Zheng, N.; Ba, X.; Yin, L.; Zhang, R.; Ma, L.; Cheng, J. "Polypeptides with Quaternary Phosphonium Side Chains: Synthesis, Characterization, and Cell-Penetrating Properties", Biomacromolecules, 2014, 15, 1491-1497. (NSF-CHE 1153122, 1DP2OD007246-01; PMC399387) Zhang, Y.; Wang, R.; Hua, Y.; Baumgartner, R.; Cheng, J. "Trigger-Responsive Poly(β-amino ester) Hydrogels", ACS Macro Letters, 2014, 3, 693-697. (Dow Chemical Company) Tong, R.; Tang, L.; Ma, L.; Tu, C.; Baumgartner, R.; Cheng, J. "Smart Chemistry in Polymeric Nanomedicines", Chemical Society Reviews, 2014, 43, 6982-7012. Zhang, R.; Zheng, N.; Song, Z.; Yin, L.; Cheng, J.; "The effect of side-chain functionality and hydrophobicity on the gene delivery capabilities of cationic helical polypeptides", Biomaterials, 2014, 35, 3443-3454. (NSF-CHE 1153122, 1DP2OD007246-01, 1R21EB013379-01; NIHMS553359) Uppada, S.B.; Erickson, T.; Wojdyla, L.; Moravec, D.N.; Song, Z.; Cheng, J.; Puri, N. "Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy", International Journal of Nanomedicine, 2014, 9, 43-53. (PMC3879016). Lu, H.; Wang, J.; Song, Z.; Yin, L.; Zhang, Y.; Tang, H.; Tu, C.; Lin, Y.; Cheng, J. "Recent Advances in Amino Acid N-Carboxyanhydrides and Synthetic Polypeptides: Chemistry, Self-Assembly and Biological Applications", Chemical Communications, 2014, 50, 139-155. Yin, Q.; Tong, R.; Yin, L.; Fan, T.M.; Cheng, J. "Anticancer Camptothecin-N-Poly(lactic acid) Nanoconjugates with Facile Hydrolysable Linker", Polymer Chemistry, 2014, 5, 1581-1585. (DMR 07-48834, NSF-DMR 1309525, 1DP2OD007246-01, 1R21CA152627; NIHMS535764) . Zheng, N.; Yin, L.; Song, Z.; Ma, L.; Tang, H.; Gabrielson, N.P.; Lu, H.; Cheng, J. "Maximizing gene delivery efficiencies of cationic helical polypeptides via balanced membrane penetration and cellular targeting", Biomaterials, 2014, 35, 1302-1314. (1DP2OD007246-01, 1R21EB013379-01, NSF-CHE-0809420; NIHMS535394)