Hamlin, Adam - University of New England - School of Science and Technology

个人简介

Dr Hamlin joined the School of Science and Technology in 2014 as a Senior Lecturer in Human Biology and Physiology (Neuroscience) moving from The School of Biomedical Sciences at Charles Sturt University where he was a Lecturer in Anatomy and Physiology. Prior to beginning his academic career in 2011 Dr Hamlin held a post-doctoral position at the Queensland Brain Institute, The University of Queensland where he was an NH&MRC Fellow investigating mechanisms of neurodegeneration in diseases such as Alzheimer's disease. Through support from the NH&MRC he continued this line of research at Charles Sturt University. Previously, he was a postdoctoral Fellow at The School of Psychology, The University of New South Wales where Dr Hamlin was investigating the neural mechanisms that underpin relapse to drug seeking behaviours. He gained his BSc (Honours) degree from the University of Queensland in 1999 and completed his PhD (Medicine) at The Pain Management Research Institute, The University of Sydney in 2006 examining the functional neuroanatomy of morphine-induced abstinence, tolerance and sensitisation.

研究领域

The focus of my research combines sophisticated functional neuroanatomical analysis with behaviour, to elucidate the neurons, circuitry and chemical underpinnings of specific behaviours. Using a functional neuroanatomical approach in combination with behavioural designs I have published several key papers relating to the functional significance of discrete neuronal populations and their circuitry. To date, this research has resulted in 19 research publications in high ranking international journals including, PLoS One, Journal of Neuroscience, Neurobiology of Learning and Memory, Behavioural Neuroscience, European Journal of Neuroscience, and Neuroimage. These research articles have been cited over 500 times (h index =13) and the recent publications elucidating a potential behavioural and MRI early detection system for Alzheimer's disease have been subject to wide spread national television radio and newspaper coverage. I have been invited to speak at several seminar series and symposia including; Neuroscience Seminar Series, Melbourne University; Translational Research 2010; 3rd Brain Plasticity Symposium: Circuits, Synapses and Behaviour; The Neuroscience Seminar Series, The University of Newcastle; Brain Sciences University of New South Wales Symposium; Australian Learning Group Christmas Workshop; Kolling Institute Seminar Series; and the XI Annual Royal North Shore Scientific Meeting as well as an invitation to speak at the inaugural Gene Regulation in Brain symposium. I am a highly sought after public lecturer, having conducted lectures at libraries, bookshops, community groups, and University of the 3rd Age and have performed many television, radio and newspaper interviews. I am currently a manuscript reviewer for a number of international journals including: Neuroscience Letters, Polish Journal of Pharmacology, Brain Research, British Journal of Pharmacology, and Spinal Cord and am currently an NHMRC grant reviewer. During my research career I have received a number of highly competitive research awards including National Health & Medical Research Council Dora Lush Biomedical Postgraduate Award, Australian Postgraduate Award (Declined), and National Health & Medical Research Council Biomedical Training Fellowship. I have attracted independent research funding from the Mason foundation and have received funding through the RIBG and CRiCS. In addition I have received $162,000 from FoS at CSU for research expenditure.

近期论文

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Rose J.L., Hamlin A.S. and Scott C. J., Sex differences in the expression of estrogen receptor-α within noradrenergic neurons in the sheep brainstem, Dom Anim Endo; 10.1016/j.domaniend, 2014. Hamlin A.S., Windels F., Boskovic Z., Sah P. and Coulson E.J., Lesions of the basal forebrain cholinergic system in mice disrupt idiothetic navigation, PLoS One; 8 (1): e53472, 2013. Kerbler G.M., Hamlin A.S., Pannek K., Kurniawan N.D., Keller M.D., Rose S.E. and Coulson E.J., Diffusion-weighted magnetic resonance imaging detection of basal forebrain cholinergic degeneration in a mouse model. Neuroimage, 66C:133-141, 2012. Walker T.L., Vukovic J., Koudijs M.M., Blackmore D.G., Mackay E.W., Sykes A.M., Overall R.W., Hamlin A.S. and Bartlett P.F., Prolactin stimulates precursor cells in the adult mouse hippocampus, PLoS One ;7(9):e44371, 2012. Kim J.H., Li S., Hamlin A.S., McNally G. P, and Richardson R., Phosphorylation of mitogen-activated protein kinase in the medial prefrontal cortex and the amygdala following memory retrieval or forgetting in developing rats, Neurobiology of Learning and Memory, 97, 59-68, 2012. Furlong T.M., Cole S., Hamlin A.S. and McNally G.P., The role ofprefrontal cortex in predictive fear learning, Behavioural Neuroscience, 124, 574-86, 2010. Jhaveri D.J., Mackay E.W., Hamlin A.S., Marathe S.V., Nandam L.S., Vaidya V.A. and Bartlett P.F., Norepinephrine Directly Activates Adult Hippocampal Precursors via β3-Adrenergic Receptors. Journal of Neuroscience, 30, 2795-2806, 2010. Kim J.H., Hamlin A.S. and Richardson R., Fear extinction across development: the involvement of the medial prefrontal cortex as assessed by temporary inactivation and immunohistochemistry. Journal of Neuroscience, 29, 10802-8, 2009. Hamlin A.S., McNally G.P., Westbrook R.F. and Osborne P.B., Induction of Fos proteins in regions of the nucleus accumbens and ventrolateral striatum correlates with catalepsy and stereotypic behaviours induced by morphine. Neuropharmacology, 56, 798–807, 2009. Marchant N.J., Hamlin A.S. and McNally G.P., Lateral hypothalamus is required for context-induced reinstatement of extinguished reward seeking. Journal of Neuroscience, 29, 1331-42, 2009. Coulson E.J., May L.M., Sykes A.M. and Hamlin A.S., The role of the p75 neurotrophin receptor in cholinergic dysfunction in Alzheimer's disease. Neuroscientist, 15, 317-23, 2009. Hamlin A.S., Clemens K.J., Choi E.A., and McNally G.P., Paraventricular thalamus mediates context induced reinstatement (renewal) of extinguished reward seeking. European Journal of Neuroscience, 29, 802-12, 2009. Hamlin A.S., Clemens K.J. and McNally G.P., Renewal of extinguished cocaine seeking. Neuroscience, 151, 659-70, 2007. Hamlin A.S., McNally G.P. and Osborne P.B., Induction of c-Fos and zif268 in the nociceptive amygdala parallel abstinence hyperalgesia in rats briefly exposed to morphine. Neuropharmacology, 53, 330-343, 2007. Hamlin A.S., Newby J., McNally G.P., The neural correlates and role of D1 dopamine receptors in renewal of extinguished alcohol-seeking. Neuroscience, 146, 525-536, 2007. Hamlin A.S., Blatchford K.E. and McNally G.P., Renewal of an extinguished instrumental response: Neural correlates and the role of D1 dopamine receptors. Neuroscience, 143, 25-38, 2006. Buller K., Hamlin A.S. and Osborne P.B., Dissection of peripheral and central endogenous opioid modulation of systemic interleukin-1b responses using c-fos expression in the rat brain. Neuropharmacology, 49, 230-242, 2004. Hamlin A.S., Buller K., Day T.A. and Osborne P.B., Effect of naloxone precipitated morphine withdrawl on c-fos expression in rat CRH neurons in the paraventricular hypothalamus and extended amygdala. Neuroscience Letters, 362, (1), 39-43, 2004. Hamlin A.S., Buller K., Day T.A. and Osborne P.B., Peripheral withdrawal recruits distinct central nuclei in morphine-dependent rats. Neuropharmacology, 41, 574 – 581, 2001.