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个人简介

After obtaining an Australia postgraduate Award, I did my PhD at Monash University, Department of Biochemistry and Cell Biology under the supervision of Dr. Alfons Lawen. Following a successful time, I was invited to the join the group at the University of Newcastle under Prof. John Aitken, which was a continuation of my PhD theme in the identifying plasma membrane redox systems. Within two years, I decided to set-up and establish a proteomics platform at the University of Newcastle and have since been successful in establishing 4 mass spectrometers in the Advanced mass spectrometry facility. In 2005 I was awarded the university of Newcastle Fellowship (rank #1 from 96 applications) which allowed 5 years of full time research. In 2011 I was awarded the NHMRC career development fellowship (level 2) from the NHMRC. I have been successful on 3 NHMRC DP grants, 1 ARC project grant and 3 ARC LIEF grants.

研究领域

Biological Sciences

近期论文

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2016 Aitken RJ, Flanagan HM, Connaughton H, Whiting S, Hedges A, Baker MA, 'Involvement of homocysteine, homocysteine thiolactone, and paraoxonase type 1 (PON-1) in the etiology of defective human sperm function.', Andrology, 4 345-360 (2016) [C1] 2016 Baker MA, 'Proteomics of post-translational modifications of mammalian spermatozoa', Cell and Tissue Research, 363 279-287 (2016) [C1] 2016 Aitken RJ, Gibb Z, Baker MA, Drevet J, Gharagozloo P, 'Causes and consequences of oxidative stress in spermatozoa', REPRODUCTION FERTILITY AND DEVELOPMENT, 28 1-10 (2016) [C1] 2016 Sutovsky P, Cupp AS, Thompson W, Baker M, 'Reproductive systems biology tackles global issues of population growth, food safety and reproductive health', CELL AND TISSUE RESEARCH, 363 1-5 (2016) 2016 Villaverde AISB, Hetherington L, Baker MA, 'Quantitative glycopeptide changes in rat sperm during epididymal transit', Biology of Reproduction, 94 (2016) 2016 Tanphaichitr N, Srakaew N, Alonzi R, Kiattiburut W, Kongmanas K, Zhi R, et al., 'Potential use of antimicrobial peptides as vaginal spermicides/microbicides', Pharmaceuticals, 9 (2016) [C1] 2016 Schneider EK, Azad MAK, Han M-L, Zhou QT, Wang J, Huang JX, et al., 'An "Unlikely" Pair: The Antimicrobial Synergy of Polymyxin B in Combination with the Cystic Fibrosis Transmembrane Conductance Regulator Drugs KALYDECO and ORKAMBI', ACS INFECTIOUS DISEASES, 2 478-488 (2016) [C1] 2015 Young SAM, Miyata H, Satouh Y, Kato H, Nozawa K, Isotani A, et al., 'CRISPR/Cas9-mediated rapid generation of multiple mouse lines identified Ccdc63 as essential for spermiogenesis', International Journal of Molecular Sciences, 16 24732-24750 (2015) [C1] 2015 Tanphaichitr N, Kongmanas K, Kruevaisayawan H, Saewu A, Sugeng C, Fernandes J, et al., 'Remodeling of the plasma membrane in preparation for sperm-egg recognition: roles of acrosomal proteins', ASIAN JOURNAL OF ANDROLOGY, 17 574-582 (2015) [C1] 2015 Baker MA, Weinberg A, Hetherington L, Villaverde AI, Velkov T, 'Analysis of protein thiol changes occurring during rat sperm epididymal maturation.', Biol Reprod, 92 11 (2015) [C1] 2015 Schneider EK, Huang JX, Carbone V, Baker M, Azad MAK, Cooper MA, et al., 'Drug-drug plasma protein binding interactions of ivacaftor', JOURNAL OF MOLECULAR RECOGNITION, 28 339-348 (2015) [C1] 2015 Kongmanas K, Kruevaisayawan H, Saewu A, Sugeng C, Fernandes J, Souda P, et al., 'Proteomic characterization of pig sperm anterior head plasma membrane reveals roles of acrosomal proteins in ZP3 binding', Journal of Cellular Physiology, 230 449-463 (2015) [C1] 2015 Aitken RJ, Baker MA, Nixon B, 'Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?', Asian J Androl, 17 633-639 (2015) [C1] 2015 Baker MA, Weinberg A, Hetherington L, Villaverde AI, Velkov T, Baell J, Gordon CP, 'Defining the mechanisms by which the reactive oxygen species by-product, 4-hydroxynonenal, affects human sperm cell function.', Biol Reprod, 92 108 (2015) [C1] 2015 Young SAM, Aitken J, Baker MA, 'Phosphorylation of Izumo1 and its role in male infertility', ASIAN JOURNAL OF ANDROLOGY, 17 708-710 (2015) [C1] 2015 Carbone V, Schneider EK, Rockman S, Baker M, Huang JX, Ong C, et al., 'Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus', MOLECULES, 20 10415-10434 (2015) [C1] 2014 Aitken RJ, Smith TB, Jobling MS, Baker MA, De Iuliis GN, 'Oxidative stress and male reproductive health', Asian Journal of Andrology, 16 31-38 (2014) [C1] 2014 Velkov T, Deris ZZ, Huang JX, Azad MAK, Butler M, Sivanesan S, et al., 'Surface changes and polymyxin interactions with a resistant strain of Klebsiella pneumoniae', INNATE IMMUNITY, 20 350-363 (2014) [C1] 2014 Baker MA, Hetherington L, Weinberg A, Velkov T, 'Phosphopeptide analysis of rodent epididymal spermatozoa', Journal of visualized experiments : JoVE, (2014) [C1] 2014 Arjomand A, Baker MA, Li C, Buckle AM, Jans DA, Loveland KL, Miyamoto Y, 'The a-importome of mammalian germ cell maturation provides novel insights for importin biology.', FASEB J, 28 3480-3493 (2014) [C1]

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