Griffiths, Lyn - Queensland University of Technology

个人简介

Professor Lyn Griffiths is the Executive Director of the Institute of Health and Biomedical Innovation (IHBI), the largest inter-disciplinary research institute at the Queensland University of Technology (QUT). She is a molecular geneticist with over 21 years experience studying human complex gene disorders with specific expertise in human gene mapping and gene expression analyses, including migraine, cardiovascular disease and several types of cancer. Research area: Professor Griffiths leads the Genomics Research Centre (GRC). Established in 1997, the GRC is a well equipped research centre including principal researchers, postdoctoral scientists, research assistants, nurses, postgraduate and honours students, and is funded by national competitive grants and industry. The main focus of research in the GRC is the identification of genes involved in common human disorders and the translation of this research into new diagnostics and therapeutics. Prof Griffiths has established significant genomic population resources for her research, including a unique case-controlled, multigenerational pedigree and genetic isolate from Norfolk Island. Recent studies at the GRC have mapped several migraine, CVD, MS and cancer gene loci and have implicated a number of candidate genes in disease susceptibility.

研究领域

Gene profiling Genetic analysis Clinical Trials

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Menon, Saras, Nasir, Bushra, Avgan, Nesli, Ghassabian, Sussan, Oliver, Christopher, Lea, Rodney A., et al. (2016) The effect of 1 mg folic acid supplementation on clinical outcomes in female migraine with aura patients. The Journal of Headache and Pain, 17(1). Maksemous, Neven, Roy, Bishakha, Smith, Robert A., & Griffiths, Lyn R. (2016) Next generation sequencing identifies novel CACNA1A gene mutations in Episodic Ataxia type 2. Molecular Genetics and Genomic Medicine, 4(2), pp. 211-222. Upadhyaya, Akanksha, Smith, Robert A., Chacon-Cortes, Diego, Revêchon, Gwladys, Bellis, Claire, Lea, Rod A., et al. (2016) Association of the microRNA-Single Nucleotide Polymorphism rs2910164 in miR146a with sporadic breast cancer susceptibility: A case control study. Gene, 576(1, Part 2), pp. 256-260. Oikari, Lotta E., Okolicsanyi, Rachel K., Qin, Aro, Yu, Chieh, Griffiths, Lyn R., & Haupt, Larisa M. (2016) Cell surface heparan sulfate proteoglycans as novel markers of human neural stem cell fate determination. Stem Cell Research, 16(1), pp. 92-104. Grealy, Rebecca, Herruer, Jasper, Smith, Carl A., Hiller, Doung, Haseler, Luke J., & Griffiths, Lyn R. (2015) Evaluation of a 7-gene genetic profile for athletic endurance phenotype in Ironman championship triathletes. Plos One, 10(12), Article Number:-e0145171. Au, Anthony, Griffiths, Lyn R., Cheng, Kian-Kai, Kooi, Cheah Wee, Irene, Looi, & Wei, Keat Loo (2015) The influence of OLR1 and PCSK9 gene polymorphisms on ischemic stroke: Evidence from a meta-analysis. Scientific Reports, 5, Article Number:-18224.