Sadowski, Pawel - Queensland University of Technology

个人简介

Pawel Sadowski completed his Ph.D. in the field of proteomics at the University of Cambridge (Cambridge, UK) under the supervision of Professor Kathryn Lilley. He then undertook postdoctoral research in the laboratories of Professor Thomas Neubert at the New York University (New York, USA) and Professor Robert Yang at the University of New South Wales (Sydney, AU). Pawel joined QUT in 2013 to lead Proteomics and Small Molecule Mass Spectrometry Core in the Central Analytical Research Facility (CARF). He supervises research that utilizes Liquid Chromatography Mass Spectrometry (LCMS) and Gas Chromatography Mass

研究领域

Pawel’s research interests include studying proteins and small molecules as dynamic entities that continuously undergo modification, conversion or relocation to explore the significance of these alterations for living organisms using high throughout approaches. Specifically, he is interested in applying cutting edge quantitative mass spectrometry techniques to investigate the dynamics of proteomes and metabolomes of species of economic importance.

近期论文

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Abbatiello SE, Schilling B, Mani D, Zimmerman LJ, Hall SC, MacLean B, Albertolle M, Allen S, Burgess M, Cusack MP, Sadowski PG, other a, (2015) Large-scale inter-laboratory study to develop, analytically validate and apply highly multiplexed, quantitative peptide assays to measure cancer-relevant proteins in plasma, Molecular and Cellular Proteomics p2357-2374 Abbatiello SE, Mani D, Schilling B, MacLean B, Zimmerman LJ, Feng X, Cusack MP, Sedransk N, Hall SC, Addona T, Sadowski PG, other a, (2013) Design, implementation and multisite evaluation of a system suitability protocol for the quantitative assessment of instrument performance in Liquid Chromatography-Multiple Reaction Monitoring-MS (LC-MRM-MS), Molecular and Cellular Proteomics p2623-2639 Cross BC, Bond PJ, Sadowski PG, Jha BK, Zak J, Goodman JM, Silverman RH, Neubert TA, Baxendale IR, Ron D, Harding HP, (2012) The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule, Proceedings of the National Academy of Sciences of the United States of America pE869-E878 Karp NA, Huber W, Sadowski PG, Charles PD, Hester SV, Lilley K, (2010) Addressing accuracy and precision issues in iTRAQ quantitation, Molecular and Cellular Proteomics p1885-1897 Trotter MW, Sadowski PG, Dunkley TP, Groen AJ, Lilley K, (2010) Improved sub-cellular resolution via simultaneous analysis of organelle proteomics data across varied experimental conditions, Proteomics p4213-4219 Sadowski PG, Groen AJ, Dupree P, Lilley K, (2008) Sub-cellular localization of membrane proteins, Proteomics p3991-4011 Maslen S, Sadowski PG, Adam A, Lilley K, Stephens E, (2006) Differentiation of isomeric N-glycan structures by normal-phase liquid chromatography-MALDI-TOF/TOF tandem mass spectrometry, Analytical Chemistry p8491-8498 Sadowski PG, Dunkley TP, Shadforth IP, Dupree P, Bessant C, Griffin JL, Lilley K, (2006) Quantitative proteomic approach to study subcellular localization of membrane proteins, Nature Protocols p1778-1789