研究领域
Dr. Melody de Laat is a clinical and research veterinarian with over 20 years experience in both clinical veterinary practice and veterinary research. Her research interests encompass disorders of metabolism and nutrition, incretin biology, endocrine dysfunction, equine lameness, veterinary pharmacology and Australian wild horse health and ecology.
Dr. de Laat’s current research projects are diverse and include analyses of the role of incretins in equine metabolic disorders, the recurrence rates of laminitis, the impact of dynamic feeding systems on obesity and metabolism and the role of insulin in equine lameness. In addition to her research and teaching commitments Dr. de Laat is a member of the University Animal Ethics Committee.
Dr de Laat is passionate about animal health and remains committed to the veterinary profession. She has published extensively on disorders of metabolism and laminitis in horses and her seminal publication on insulin toxicity in horses has been listed by Thomson’s ISI among the top 1% of papers published in the plant and animal sciences category since 2010 and was the most cited article in the journal in 2012. She has also received a Discovery Early Career Research Award to continue her research into incretin biology.
近期论文
查看导师新发文章
（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）
de Laat MA, McGree JM, Sillence MN, (2016) Equine hyperinsulinemia: investigation of the enteroinsular axis during insulin dysregulation, AJP: Endocrinology and Metabolism pE61-E72
de Laat MA, Van Haeften JJ, Sillence MN, (2016) The effect of oral and intravenous dextrose on C-peptide secretion in ponies, Journal of Animal Science p574-580
de Laat M, Clement C, Sillence MN, McGowan C, Pollitt CC, Lacombe VA, (2015) The impact of prolonged hyperinsulinaemia on glucose transport in equine skeletal muscle and digital lamellae, Equine Veterinary Journal p494-501
de Laat M, Gruntmeir KJ, Pollitt CC, McGowan C, Sillence MN, Lacombe VA, (2014) Hyperinsulinemia down-regulates TLR4 expression in the mammalian heart, Frontiers in Endocrinology p1-8
de Laat MA, (2014) Metabolic dysfunction and laminitis, Australian Equine Veterinarian p44-52
de Laat M, Clement CK, McGowan C, Sillence MN, Pollitt CC, Lacombe VA, (2014) Toll-like receptor and pro-inflammatory cytokine expression during prolonged hyperinsulinaemia in horses: Implications for laminitis, Veterinary Immunology and Immunopathology p78-86
de Laat M, Pollitt CC, Kyaw-Tanner M, McGowan C, Sillence MN, (2013) A potential role for lamellar insulin-like growth factor-1 receptor in the pathogenesis of hyperinsulinaemic laminitis, The Veterinary Journal p302-306
De-laat M, Kyaw-Tanner M, Sillence MN, McGowan C, Pollitt CC, (2012) Advanced glycation endproducts in horses with insulin-induced laminitis, Veterinary Immunology and Immunopathology p395-401
De-laat M, Sillence MN, McGowan C, Pollitt CC, (2012) Continuous intravenous infusion of glucose induces endogenous hyperinsulinaemia and lamellar histopathology in Standardbred horses, Veterinary Journal p317-322
De-laat M, McGowan C, Sillence MN, Pollit C, (2010) Equine laminitis: Induced by 48 h hyperinsulinaemia in Standardbred horses, Equine Veterinary Journal p129-135
京公网安备 11010802027423号