研究领域
1) Structure and function of ion channels.
2) Ion channels and cancer.
3) Drug discovery targeting ion channels.
近期论文
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1) Anti-tumor effects of (1→3)-β-d-glucan from Saccharomyces cerevisiae in S180 tumor-bearing mice[J]. Mo L , Chen Y , Li W ,Guo S, Wang X, An H*, Zhan Y*, International Journal of Biological Macromolecules, 2017, 95: 385–392.
2) Tetrandrine, a novel inhibitor of ether-à-go-go-1 (Eag1), targeted to cervical cancer development[J]. Wang X , Chen Y , Li J ,Guo S, Lin X, Zhang H, Zhan Y*, An H*. Journal of Cellular Physiology, 2018.
3) Matrine is a novel inhibitor of the TMEM16A chloride channel with antilung adenocarcinoma effects[J]. Guo S , Chen Y , Pang C , Wang X, Shi S, Zhang H, An H*, Zhan Y*, Journal of Cellular Physiology, 2019, 234(6):8698-8708.
4) Recent advances in TMEM16A: Structure, function, and disease[J]. Ji Q, Guo S, Wang X, Pang C, Zhan Y, Chen Y*, An H*, Journal of Cellular Physiology, 2019, 234(6):7856-7873.
5) Entering the spotlight: Chitosan oligosaccharides as novel activators of CaCCs/TMEM16A[J]. Guo S , Wang H , Pang C , Ren X, Li J, Wang X, Shi S, Qi J, Zhang H, Zhan Y, Chen Y*, An H*, Pharmacological research, 2019, 146:104323.
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