个人简介
Professor RP Hellens joined the Centre for Tropical Crop and Biocomodities in March 2014.
From 2000 to 2014 he worked in New Zealand at Plant&Food (aka HortResearch) in Auckland, where he had a number of role including leading the institutes 80-people strong genomics research and more recently the $10M p.a. kiwifruit breeding programme.
Prior to his move to New Zealand, Professor Hellens worked at the John Innes Centre in Norwich, UK. Here he developed the first genetic maps in pea (including his PhD on the molecular basis of Mendel’s white flower phenotype), He developed the pGreen plant transformation vector and a project on gene silencing (RNAi) in petunia.
研究领域
His research interests were the development of red-fleshed apple and kiwifruit varieties and exploiting Next Generation Sequencing (NGS) techniques. He has also maintained a keen interest in post transcriptional gene regulation and this has become relevant in work to understand the regulation of vitamin C.
近期论文
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Waterhouse PM, Hellens RP, (2015) Plant biology: Coding in non-coding RNAs, Nature p41-42
Laing WA, Martinez-Sanchez M, Wright M, Bulley SM, Brewster D, Dare AP, Rassam M, Wang D, Storey RD, Macknight RC, Hellens RP, (2015) An upstream open reading frame Is essential for feedback regulation of ascorbate biosynthesis in arabidopsis, The Plant Cell p772-786
Espley RV, Butts CA, Laing WA, Martell S, Smith H, McGhie TK, Zhang J, Paturi G, Hedderley D, Bovy A, Schouten HJ, Putterill J, Allan AC, Hellens RP, (2014) Dietary flavonoids from modified apple reduce inflammation markers and modulate gut microbiota in mice, Journal of Nutrition p146-154
Espley RV, Bovy A, Bava C, Jaeger SR, Tomes S, Norling C, Crawford J, Rowan D, McGhie TK, Brendolise C, Putterill J, Schouten HJ, Hellens RP, Allan AC, (2013) Analysis of genetically modified red-fleshed apples reveals effects on growth and consumer attributes, Plant Biotechnology Journal p408-419
Dare AP, Tomes S, Jones M, McGhie TK, Stevenson DE, Johnson RA, Greenwood DR, Hellens RP, (2013) Phenotypic changes associated with RNA interference silencing of chalcone synthase in apple (Malus X domestica), Plant Journal p398-410
Naim F, Nakasugi K, Crowhurst RN, Hilario E, Zwart AB, Hellens RP, Taylor JM, Waterhouse P, Wood C, (2012) Advanced Engineering of Lipid Metabolism in Nicotiana benthamiana Using a Draft Genome and the V2 Viral Silencing-Suppressor Protein, PLoS ONE p1-11
Shulaev V, Sargent D, Crowhurst RN, Mockler T, Folkerts O, Delcher A, Jaiswal P, Mockaitis K, Liston A, Mane S, Hellens RP, other a, (2011) The genome of woodland strawberry (Fragaria vesca), Nature Genetics p109-116
Hellens RP, Moreau C, Lin-Wang K, Schwinn KE, Thomson SJ, Fiers MW, Frew TJ, Murray SR, Hofer JM, Jacobs JM, Davies KM, Allan AC, Bendahmane A, Coyne CJ, Timmerman-Vaughan GM, Ellis NT, (2010) Identification of Mendel's white flower character, PLoS ONE p1-8
Velasco R, Zharkikh A, Affourtit J, Dhingra A, Cestaro A, Kalyanaraman A, Fontana P, Bhatnagar SK, Troggio M, Pruss D, Hellens RP, other a, (2010) The genome of the domesticated apple (Malus x domestica Borkh.), Nature Genetics p833-839
Espley RV, Brendolise C, Chagne D, Kutty-Amma S, Green S, Volz RK, Putterill J, Schouten HJ, Gardiner SE, Hellens RP, Allan AC, (2009) Multiple repeats of a promoter segment causes transcription factor autoregulation in red apples, Plant Cell p168-183