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个人简介

复旦大学类脑智能科学与技术研究院青年研究员,博士生导师。复旦大学认知神经科学中心执行主任。2007年毕业于西安交通大学,2012年于复旦大学获得神经生物学博士学位后,进入耶鲁大学医学院进行博士后研究,于2017年聘为耶鲁大学副研究员。 2018年作为海外高层次人才引进加入复旦大学,被评选为2019年上海市青年科技启明星,并担任上海市民建人工智能专委会副主任。获得“变革性技术关键科学问题” 国家重点研发计划、国家自然基金“青年项目”、 上海市“脑与类脑智能基础转化应用研究”重大科技专项子课题、美国AHA FDA项目等研究资助。研究专长为使用认知心理学、分子基因工程改造、脑电生理结合双光子成像和计算神经科学等交叉学科手段,对情感障碍和认知缺陷的神经环路和分子机制进行深入探究,并为脑内超微环路中单突触可塑性的记录建立新型实验方法,取得了一系列重要成果。以第一作者或通讯作者在神经生物学权威期刊:Cell Reports ,Neuroscience Biobehavioral Reviews,Cerebral Cortex,Journal of Neuroscience, Pain, Anesthesiology等多次发表研究论文。长期担任国际学术期刊J Biomed. Sci.、CPQ Medicine和 J. Psychiatric & Mental Health 编委,多次担任Hippocampus,Neurobiology of aging,Journal of Neuroscience等SCI期刊审稿专家,并组织美国Keystone Symposia: Synapse and Circuits 会议(2017)及上海-剑桥研讨会(2019,2020,2021)。与杨雄里院士合著中文科普专著《探索脑的奥秘》,翻译神经外科医生Oliver Sacks著作《最初的爱,最后的故事》。

研究领域

情绪和学习记忆相关疾病的神经环路与分子机制

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

A tassel-type multilayer flexible neural probe prepared by laser direct writing. Zipeng Ye, Jing Qi, Yiling Ni, Zhiyong Wu, Xiao Xiao#, Shisheng Xiong#, Chip, (2022). Accepted. (Cover paper) Corticospinal circuit neuroplasticity may involve silent synapses: implications for functional recovery facilitated by neuromodulation after spinal cord injury. Mingcong Chen, Zuxin Chen, Xiao Xiao, Libing Zhou, Rao Fu, Xian Jiang, Mao Pang, Jianxun Xia#, IBRO Neuroscience Reports (2022). Accepted The role of glia underlying acupuncture analgesia in animal pain models, a systematic review and meta-analysis. Bing Yan, Shengyu Tang, Yuqiu Zhang, Xiao Xiao#, Pain Medicine (2022). Accepted Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice. Lu Luo*, Meixi Liu*, Yunhui Fan, Jingjun Zhang, Li Liu, Yun Li, Qiqi Zhang, Hongyu Xie, Congyu Jiang, Junfa Wu, Xiao Xiao#, Yi Wu#, Journal of Neuroinflammation (2022) 19:141 Neurophysiological characteristics in the periventricular/periaqueductal gray correlate with pain perception, sensation, and affect in neuropathic pain patients. Huichun Luo*, Yongzhi Huang*, Alexander L. Green, Tipu Z. Aziz, Xiao Xiao, Shouyan Wang#, NeuroImage: Clinical (2021). 32, 102876 MonkeyPosekit: Automated Markerless 2D Pose Estimation of Monkey, Chuxi Li, Chi Yang, Yerong Li, Shufei Feng, Zhen Zhang, Shisheng Xiong#, Xiao Xiao#, IEEE- China Automation Congress (CAC) (2021) 1280-1284 基于时移和片组注意力融合的双流行为识别网络. 肖子凡, 刘逸群, 李楚溪, 张力, 王守岩, 肖晓#计算机系统应用 Computer Systems & Applications, (2022) 31(1):204?211 The role of the anterior cingulate cortex in translational pain research. Xiao Xiao#, Ming Ding, Yuqiu Zhang#, Neuroscience Bulletin (2021) 37(3), 405-422 Distinct function of estrogen receptors in the rodent anterior cingulate cortex in pain-related aversion. Kai-Kai Zang *, Xiao Xiao*,Li-Qiang Chen,Yan Yang, Qi-Lai Cao, Yu-Long Tang, Su-Su Lv, Hong Cao, Ling Zhang, Yu-Qiu Zhang. Anesthesiology (2020) Jul;133(1):165-184; Functional dynamics of thalamic local field potentials correlated with modulation of neuropathic pain. Huichun Luo, Yongzhi Huang, Xiao Xiao, Wenjing Dai, Yingnan Nie, Xinyi Geng, Yongzhi Huang, Alex Green, Tipu Aziz, Shouyan Wang#, European Journal of Neuroscience. (2020) 51:628–640 Trio haploinsufficiency causes neurodevelopmental disease-associated deficits. Sara M. Katrancha, Amy Zhao, Amanda Jeng, Juliana Shaw, Minsheng Zhu, Christopher Pittenger, Charles Greer, Xiao Xiao#, Anthony J. Koleske# Cell Reports. (2019) 26:2805-2817 A new perspective on the anterior cingulate cortex and affective pain. Xiao Xiao, Yuqiu Zhang*. Neuroscience & Biobehavioral Reviews (2018) 90:200-211 Noonan syndrome-associated SHP2 dephosphorylates GluN2B to regulate NMDA receptor function. Aaron D. Levy*, Xiao Xiao*, Suma Priya Sudarsana Devi, Anton M. Bennett, Charles A. Greer, James R. Howe, Kazuya Machida, Anthony J. Koleske# Cell Reports (2018) 24 (6):1523-1535 CNS neurons deposit Laminin α5 to stabilize synapses. Mitchell H. Omar, Maghan Kerrisk Campbell, Xiao Xiao, Qiaonan Zhong, William J. Brunken, Jeffrey H. Miner, Charles A. Greer, Anthony J. Koleske#, Cell Reports (2017) 21(5): 1281-1292 Disruption of coordinated presynaptic and postsynaptic maturation underlies the defects in hippocampal synapse stability and plasticity in Abl2/Arg-deficient mice. Xiao Xiao, Aaron D. Levy, Brian J. Rosenberg, Michael J. Higley, Anthony J. Koleske#, Journal of Neuroscience, (2016) 36 (25): 6778-6791 SIP 30 Is Required for Neuropathic Pain-Evoked Aversion in Rats. Mei Han, Xiao Xiao, Yan Yang, Ru-Yi Huang, Hong Cao, Zhi-Qi Zhao, Yu-Qiu Zhang#, Journal of Neuroscience,(2014) 34(2): 346-355 Estrogen in the anterior cingulate cortex contributes to pain-related aversion. Xiao Xiao, Yan Zhang, Yan Yang, Zhi-Qi Zhao, Yu-Qiu Zhang#, Cerebral Cortex (2012) 23(9): 2190-2203 Estrogen facilitates spinal cord synaptic transmission via mambrane-bound estrogen receptors: implications for pain hypersensitivity. Yan Zhang,Xiao Xiao, Zhi-Qi Zhao, Yu-Qiu Zhang#, Journal of Biological Chemistry,(2012) 287(40):33268-81 综述:一念放下,万般自在——我们能否训练自己去遗忘疼痛. 肖晓, 生理学报Acta Physiologica Sinica, June 25, 2011, 63(3): 293–295 NMDA NR2A and NR2B receptors in the rostral anterior cingulate cortex contribute to pain-related aversion in male rats. Ting-Ting Li*, Wen-Hua Ren*, Xiao Xiao*, Long-Zhen Cheng, Xue-Han Zhang, Zhi-Qi Zhao, Yu-Qiu Zhang#. Pain, (2009) 146, 183–193

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