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个人简介

Luis Pedro Coelho一直利用大数据的方法从事生物学研究。尤其专注于利用元基因组及荧光显微图像法对微生物群体进行分析。加入复旦之前,路易斯.佩德罗.科埃略一直在欧洲分子生物学实验室(EMBL)Peer Bork院士组中从事博士后研究。路易斯.佩德罗.科埃略师从Bob Murphy并在卡内基梅隆大学获得博士学位,师从Prof Arlindo Oliveira在Instituto Superior Técnico in Lisbon获得硕士学位。在Nature、Science和eLife等国际著名期刊发表SCI论文30余篇,开发多个生物图像处理和微生物组学数据分析软件包。

研究领域

计算生物 微生物组及微生物生态学 大数据及机器学习

近期论文

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Ubiquity of inverted ’gelatinous’ ecosystem pyramids in the global ocean by Lombard Fabien, Guidi Lionel, Manoela C. Brand?o, Coelho Luis Pedro, Colin Sébastien, Dolan John Richard, Elineau Amanda, Josep M Gasol, Grondin Pierre Luc, Henry Nicolas, Federico M Ibarbalz, Jalabert La?titia, Loreau Michel, Martini Séverinne, Mériguet Zoé, Picheral Marc, Juan José Pierella Karlusich, Rainer Pepperkok, Romagnan Jean-Baptiste, Zinger Lucie, Stemmann Lars, Silvia G Acinas, Karp-Boss Lee, Boss Emmanuel, Matthew B. Sullivan, Colomban de Vargas, Bowler Chris, Karsenti Eric, Gorsky Gabriel, Tara Oceans Coordinators in biorXiv (PREPRINT) (2024). A catalogue of small proteins from the global microbiome by Yiqian Duan, Célio Dias Santos Júnior, Thomas S.B. Schmidt, Anthony Fullam, Breno L. S. de Almeida, Chengkai Zhu, Kuhn Michael, Xing-Ming Zhao, Peer Bork, Luis Pedro Coelho in bioRxiv (PREPRINT) (2023). Functional and evolutionary significance of unknown genes from uncultivated taxa by álvaro Rodríguez del Río, Joaquín Giner-Lamia, Carlos P. Cantalapiedra, Jorge Botas, Ziqi Deng, Ana Hernández-Plaza, Martí Munar-Palmer, Saray Santamaría-Hernando, José J. Rodríguez-Herva, Hans-Joachim Ruscheweyh, Lucas Paoli, Thomas S. B. Schmidt, Shinichi Sunagawa, Peer Bork, Emilia López-Solanilla, Luis Pedro Coelho, Jaime Huerta-Cepas in Nature (2023). SPIRE: a Searchable, Planetary-scale mIcrobiome REsource by Thomas S B Schmidt, Anthony Fullam, Pamela Ferretti, Askarbek Orakov, Oleksandr M Maistrenko, Hans-Joachim Ruscheweyh, Ivica Letunic, Yiqian Duan, Thea Van Rossum, Shinichi Sunagawa, Daniel R Mende, Robert D Finn, Michael Kuhn, Luis Pedro Coelho, Peer Bork in Nucleic Acids Research (2023). Computational exploration of the global microbiome for antibiotic discovery by Célio Dias Santos-Júnior, Marcelo Der Torossian Torres, Yiqian Duan, álvaro Rodríguez del Río, Thomas S.B. Schmidt, Hui Chong, Anthony Fullam, Michael Kuhn, Chengkai Zhu, Amy Houseman, Jelena Somborski, Anna Vines, Xing-Ming Zhao, Peer Bork, Jaime Huerta-Cepas, Cesar de la Fuente-Nunez, Luis Pedro Coelho in biorXiv (PREPRINT) (2023). Towards Monitoring of Antimicrobial Resistance in the Environment: For what Reasons, How to Implement It, and What Are the Data Needs? by Johan Bengtsson-Palme, Anna Abramova, Thomas U. Berendonk, Luis Pedro Coelho, Sofia K. Forslund, Rémi Gschwind, Annamari Heikinheimo, Víctor Hugo Jarquín-Díaz, Ayaz Ali Khan, Uli Klümper, Ulrike L?ber, Marmar Nekoro, Adriana D. Osińska, Svetlana Ugarcina Perovic, Tarja Pitk?nen, Ernst Kristian R?dland, Etienne Ruppé, Yngvild Wasteson, Astrid Louise Wester, Rabaab Zahra in Environment International (2023). A global survey of eco-evolutionary pressures acting on horizontal gene transfer by Marija Dmitrijeva, Janko Tackmann, Jo?o Matias Rodrigues, Jaime Huerta-Cepas, Luis Pedro Coelho, Christian von Mering in Research Square (PREPRINT) (2023). ResFinderFG v2.0: a database of antibiotic resistance genes obtained by functional metagenomics by Rémi Gschwind, Svetlana Ugarcina Perovic, Maja Weiss, Marie Petitjean, Julie Lao, Luis Pedro Coelho, Etienne Ruppé in Nucleic Acids Research (2023). SemiBin2: self-supervised contrastive learning leads to better MAGs for short- and long-read sequencing by Shaojun Pan, Xing-Ming Zhao, Luis Pedro Coelho in Bioinformatics (2023). metaMIC: reference-free misassembly identification and correction of de novo metagenomic assemblies by Senying Lai, Shaojun Pan, Chuqing Sun, Luis Pedro Coelho, Wei-Hua Chen, Xing-Ming Zhao in Genome Biology (2022). Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide with implications for heart and kidney disorders by Petros Andrikopoulos, Judith Aron-Wisnewsky, Rima Chakaroun, Antonis Myridakis, Sofia K. Forslund, Trine Nielsen, Solia Adriouch, Bridget Holmes, Julien Chilloux, Sara Vieira-Silva, Gwen Falony, Joe-Elie Salem, Fabrizio Andreelli, Eugeni Belda, Julius Kieswich, Kanta Chechi, Francesc Puig-Castellvi, Mickael Chevalier, Emmanuelle Le Chatelier, Michael T. Olanipekun, Lesley Hoyles, Renato Alves, Gerard Helft, Richard Isnard, Lars K?ber, Luis Pedro Coelho, Christine Rouault, Dominique Gauguier, Jens Peter G?tze, Edi Prifti, Jean-Daniel Zucker, Fredrik B?ckhed, Henrik Vestergaard, Torben Hansen, Jean-Michel Oppert, Matthias Blüher, Jens Nielsen, Jeroen Raes, Peer Bork, Muhammad M. Yaqoob, Michael Stumvoll, Oluf Pedersen, S. Dusko Ehrlich, Karine Clément, Marc-Emmanuel Dumas, MetaCardis Consortium in medRXiv (PREPRINT) (2022). EXPERT: Transfer Learning-enabled context-aware microbial source tracking by Hui Chong, Yuguo Zha, Qingyang Yu, Mingyue Cheng, Guangzhou Xiong, Nan Wang, Xinhe Huang, Shijuan Huang, Chuqing Sun, Sicheng Wu, Weihua Chen, Luis Pedro Coelho, Kang Ning in Briefings in Bioinformatics (2022). Drivers and Determinants of Strain Dynamics Following Faecal Microbiota Transplantation by Thomas SB Schmidt, Simone S Li, Oleksandr M Maistrenko, Wasiu Akkani, Luis Pedro Coelho, Sibasish Dolai, Anthony Fullam, Anna Glazek, Rajna Hercog, Hilde Herrema in Nature Medicine (2022). A deep siamese neural network improves metagenome-assembled genomes in microbiome datasets across different environments by Shaojun Pan, Chengkai Zhu, Xing-Ming Zhao, Luis Pedro Coelho in Nature Communications (2022). Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes by Supriya Khedkar, Georgy Smyshlyaev, Ivica Letunic, Oleksandr M Maistrenko, Luis Pedro Coelho, Askarbek Orakov, Sofia K Forslund, Falk Hildebrand, Mechthild Luetge, Thomas S B Schmidt, Orsolya Barabas, Peer Bork in Nucleic Acids Research (2022). Software testing in microbial bioinformatics: a call to action by Boas C.L. van der Putten, C. I. Mendes, Brooke M. Talbot, Jolinda de Korne-Elenbaas, Rafael Mamede, Pedro Vila-Cerqueira, Luis Pedro Coelho, Christopher A. Gulvik, Lee S. Katz, The ASM NGS 2020 Hackathon participants in Microbial Genomics (2022). Microbiome and metabolome features of the cardiometabolic disease spectrum by Sebastien Fromentin, Sofia K. Forslund, Kanta Chechi, Judith Aron-Wisnewsky, Rima Chakaroun, Trine Nielsen, Valentina Tremaroli, Boyang Ji, Edi Prifti, Antonis Myridakis, Julien Chilloux, Petros Andrikopoulos, Yong Fan, Michael T. Olanipekun, Renato Alves, Solia Adiouch, Noam Bar, Yeela Talmor-Barkan, Eugeni Belda, Robert Caesar, Luis Pedro Coelho, Gwen Falony, Soraya Fellahi, Pilar Galan, Nathalie Galleron, Gerard Helft, Lesley Hoyles, Richard Isnard, Emmanuelle Le Chatelier, Hanna Julienne, Lisa Olsson, Helle Krogh Pedersen, Nicolas Pons, Benoit Quinquis, Christine Rouault, Hugo Roume, Joe-Elie Salem, Thomas S. B. Schmidt, Sara Vieira-Silva, Peishun Li, Maria Zimmermann-Kogadeeva, Christian Lewinter, Nadja B. S?ndertoft, Tue H. Hansen, Dominique Gauguier, Jens Peter G?tze, Lars K?ber, Ran Kornowski, Henrik Vestergaard, Torben Hansen, Jean-Daniel Zucker, Serge Hercberg, Ivica Letunic, Fredrik B?ckhed, Jean-Michel Oppert, Jens Nielsen, Jeroen Raes, Peer Bork, Michael Stumvoll, Eran Segal, Karine Clément, Marc-Emmanuel Dumas, S. Dusko Ehrlich, Oluf Pedersen in Nature Medicine (2022). Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism by Eugeni Belda, Lise Voland, Valentina Tremaroli, Gwen Falony, Solia Adriouch, Karen E Assmann, Edi Prifiti, Judith Aron-Wisnewsky, Jean Debédat, Tiphaine Le Roy, Trine Nielsen, Chloé Amouyal, Sébastien André, Fabrizio Andreelli, Matthias Blüher, Rima Chakaroun, Julien Chilloux, Luis Pedro Coelho, Maria Carlota Dao, Promi Das, Soraya Fellahi, Sofia Forslund, Nathalie Galleron, Tue H Hansen, Bridget Holmes, Boyang Ji, Helle Krogh Pedersen, Phuong Le, Emmanuelle Le Chatelier, Christian Lewinter, Louise Manner?s-Holm, Florian Marquet, Antonis Myridakis, Veronique Pelloux, Nicolas Pons, Benoit Quinquis, Christine Rouault, Hugo Roume, Joe-Elie Salem, Nataliya Sokolovska, Nadja B S?ndertoft, Sothea Touch, Sara Vieira-Silva, Pilar Galan, Jens Holst, Jens Peter G?tze, Lars K?ber, Henrik Vestergaard, Torben Hansen, Serge Hercberg, Jean-Michel Oppert, Jens Nielsen, Ivica Letunic, Marc-Emmanuel Dumas, Michael Stumvoll, Oluf Borbye Pedersen, Peer Bork, Stanislav Dusko Ehrlich, Jean-Daniel Zucker, Fredrik B?ckhed, Jeroen Raes, Karine Clément, The MetaCardis Consortium in Gut (2022). Towards the biogeography of prokaryotic genes by Luis Pedro Coelho, Renato Alves, álvaro Rodríguez del Río, Pernille Neve Myers, Carlos P. Cantalapiedra, Joaquín Giner-Lamia, Thomas Sebastian Schmidt, Daniel R. Mende, Askarbek Orakov, Ivica Letunic, Falk Hildebrand, Thea Van Rossum, Sofia K. Forslund, Supriya Khedkar, Oleksandr M. Maistrenko, Shaojun Pan, Longhao Jia, Pamela Ferretti, Shinichi Sunagawa, Xing-Ming Zhao, Henrik Bj?rn Nielsen, Jaime Huerta-Cepas, Peer Bork in Nature (2021), [Open Access version]. An open code pledge for the neuroscience community by Cooper Smout, Dawn Liu Holford, Kelly Garner, ruddy manuel illanes beyuma, Paula Andrea Martinez, Megan Ethel Janine Campbell, Ibrahim Khormi, Dylan G. E. Gomes, Johanna Margarete Marianne Bayer, Claire Bradley, Antonio Schettino, Naoyuki Sunami, Sina Mansour L., Luis Pedro Coelho in MetaArXiv Preprint (2021). Combinatorial, additive and dose-dependent drug–microbiome associations by Sofia K. Forslund, Rima Chakaroun, Maria Zimmermann-Kogadeeva, Lajos Markó, Judith Aron-Wisnewsky, Trine Nielsen, Lucas Moitinho-Silva, Thomas S. B. Schmidt, Gwen Falony, Sara Vieira-Silva, Solia Adriouch, Renato J. Alves, Karen Assmann, Jean-Philippe Bastard, Till Birkner, Robert Caesar, Julien Chilloux, Luis Pedro Coelho, Leopold Fezeu, Nathalie Galleron, Gerard Helft, Richard Isnard, Boyang Ji, Michael Kuhn, Emmanuelle Le Chatelier, Antonis Myridakis, Lisa Olsson, Nicolas Pons, Edi Prifti, Benoit Quinquis, Hugo Roume, Joe-Elie Salem, Nataliya Sokolovska, Valentina Tremaroli, Mireia Valles-Colomer, Christian Lewinter, Nadja B. S?ndertoft, Helle Krogh Pedersen, Tue H. Hansen, Chloe Amouyal, Ehm Astrid Andersson Galijatovic, Fabrizio Andreelli, Olivier Barthelemy, Jean-Paul Batisse, Eugeni Belda, Magalie Berland, Randa Bittar, Hervé Blottière, Frederic Bosquet, Rachid Boubrit, Olivier Bourron, Mickael Camus, Dominique Cassuto, Cecile Ciangura, Jean-Philippe Collet, Maria-Carlota Dao, Morad Djebbar, Angélique Doré, Line Engelbrechtsen, Soraya Fellahi, Sebastien Fromentin, Pilar Galan, Dominique Gauguier, Philippe Giral, Agnes Hartemann, Bolette Hartmann, Jens Juul Holst, Malene Hornbak, Lesley Hoyles, Jean-Sebastien Hulot, Sophie Jaqueminet, Niklas Rye J?rgensen, Hanna Julienne, Johanne Justesen, Judith Kammer, Nikolaj Krarup, Mathieu Kerneis, Jean Khemis, Ruby Kozlowski, Véronique Lejard, Florence Levenez, Lea Lucas-Martini, Robin Massey, Laura Martinez-Gili, Nicolas Maziers, Jonathan Medina-Stamminger, Gilles Montalescot, Sandrine Moute, Ana Luisa Neves, Michael Olanipekun, Laetitia Pasero Le Pavin, Christine Poitou, Francoise Pousset, Laurence Pouzoulet, Andrea Rodriguez-Martinez, Christine Rouault, Johanne Silvain, Mathilde Svendstrup, Timothy Swartz, Thierry Vanduyvenboden, Camille Vatier, Stefanie Walther, Jens Peter G?tze, Lars K?ber, Henrik Vestergaard, Torben Hansen, Jean-Daniel Zucker, Serge Hercberg, Jean-Michel Oppert, Ivica Letunic, Jens Nielsen, Fredrik B?ckhed, S. Dusko Ehrlich, Marc-Emmanuel Dumas, Jeroen Raes, Oluf Pedersen, Karine Clément, Michael Stumvoll, Peer Bork, The MetaCardis Consortium* in Nature (2021). GUNC: detection of chimerism and contamination in prokaryotic genomes by Askarbek Orakov, Anthony Fullam, Luis Pedro Coelho, Supriya Khedkar, Damian Szklarczyk, Daniel R Mende, Thomas SB Schmidt, Peer Bork in Genome Biology (2021). MACREL: antimicrobial peptide screening in genomes and metagenomes by Célio Dias Santos-Junior, Shaojun Pan, Xing-Ming Zhao, Luis Pedro Coelho in PeerJ (2020). Metagenomic assessment of the global diversity and distribution of bacteria and fungi by Mohammad Bahram, Tarquin Netherway, Clémence Frioux, Pamela Ferretti, Luis Pedro Coelho, Stefan Geisen, Peer Bork, Falk Hildebrand in Environmental Microbiology (2021). Voices of the new generation: science in a state of benign confusion by Luis Pedro Coelho in Nature Reviews Molecular Cell Biology (2020). Statin therapy is associated with lower prevalence of gut microbiota dysbiosis by Sara Vieira-Silva, Gwen Falony, Eugeni Belda, Trine Nielsen, Judith Aron-Wisnewsky, Rima Chakaroun, Sofia K Forslund, Karen Assmann, Mireia Valles-Colomer, Thi Thuy Duyen Nguyen, Sebastian Proost, Edi Prifti, Valentina Tremaroli, Nicolas Pons, Emmanuelle Le Chatelier, Fabrizio Andreelli, Jean-Phillippe Bastard, Luis Pedro Coelho, Nathalie Galleron, Tue H. Hansen, Jean-Sébastien Hulot, Christian Lewinter, Helle K. Pedersen, Benoit Quinquis, Christine Rouault, Hugo Roume, Joe-Elie Salem, Nadja B. S?ndertoft, Sothea Touch, MetaCardis Consortium, Marc-Emmanuel Dumas, Stanislav Dusko Ehrlich, Pilar Galan, Jens P. G?tze, Torben Hansen, Jens J. Holst, Lars K?ber, Ivica Letunic, Jens Nielsen, Jean-Michel Oppert, Michael Stumvoll, Henrik Vestergaard, Jean-Daniel Zucker, Peer Bork, Oluf Pedersen, Fredrik B?ckhed, Karine Clément, Jeroen Raes in Nature (2020). Disentangling the impact of environmental and phylogenetic constraints on prokaryotic within-species diversity by Oleksandr M Maistrenko, Daniel R Mende, Mechthild Luetge, Falk Hildebrand, Thomas SB Schmidt, Simone S Li, Jo?o F Matias Rodrigues, Christian von Mering, Luis Pedro Coelho, Jaime Huerta-Cepas, Shinichi Sunagawa, Peer Bork in The ISME Journal (2020). Gene Expression Changes and Community Turnover Differentially Shape the Global Ocean Metatranscriptome by Guillem Salazar, Lucas Paoli, Adriana Alberti, Jaime Huerta-Cepas, Hans-Joachim Ruscheweyh, Miguelangel Cuenca, Christopher M Field, Luis Pedro Coelho, Corinne Cruaud, Stefan Engelen, Ann C. Gregory, Karine Labadie, Claudie Marec, Eric Pelletier, Marta Royo-Llonch, Simon Roux, Pablo Sánchez, Hideya Uehara, Ahmed A. Zayed, Georg Zeller, Margaux Carmichael, Céline Dimier, Joannie Ferland, Stefanie Kandels, Marc Picheral, Sergey Pisarev, Julie Poulain, Tara Oceans Coordinators, Silvia G. Acinas, Marcel Babin, Peer Bork, Chris Bowler, Colomban de Vargas, Lionel Guidi, Pascal Hingamp, Daniele Iudicone, Lee Karp-Boss, Eric Karsenti, Hiroyuki Ogata, Stephane Pesant, Sabrina Speich, Matthew B. Sullivan, Patrick Wincker, Shinichi Sunagawa in Cell (2019). Global trends in marine plankton diversity across kingdoms of life by Federico M Ibarbalz, Nicolas Henry, Manoela C Brand?o, Séverine Martini, Greta Busseni, Hannah Byrne, Luis Pedro Coelho, Hisashi Endo, Josep M Gasol, Ann C Gregory in Cell (2019). proGenomes2: an improved database for accurate and consistent habitat, taxonomic and functional annotations of prokaryotic genomes by Daniel R Mende, Ivica Letunic, Oleksandr M Maistrenko, Thomas SB Schmidt, Alessio Milanese, Lucas Paoli, Ana Hernández-Plaza, Askarbek N Orakov, Sofia K Forslund, Shinichi Sunagawa, Georg Zeller, Jaime Huerta-Cepas, Luis Pedro Coelho, Peer Bork in Nucleic acids research (2020). Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer by Jakob Wirbel, Paul Theodor Pyl, Ece Kartal, Konrad Zych, Alireza Kashani, Alessio Milanese, Jonas S Fleck, Anita Y Voigt, Albert Palleja, Ruby Ponnudurai, Shinichi Sunagawa, Luis Pedro Coelho, Petra Schrotz-King, Emily Vogtmann, Nina Habermann, Emma Niméus, Andrew M. Thomas, Paolo Manghi, Sara Gandini, Davide Serrano, Sayaka Mizutani, Hirotsugu Shiroma, Satoshi Shiba, Tatsuhiro Shibata, Shinichi Yachida, Takuji Yamada, Levi Waldron, Alessio Naccarati, Nicola Segata, Rashmi Sinha, Cornelia M. Ulrich, Hermann Brenner, Manimozhiyan Arumugam, Peer Bork, Georg Zeller in Nature medicine (2019). Microbial abundance, activity and population genomic profiling with mOTUs2 by Alessio Milanese, Daniel R Mende, Lucas Paoli, Guillem Salazar, Hans-Joachim Ruscheweyh, Miguelangel Cuenca, Pascal Hingamp, Renato Alves, Paul I Costea, Luis Pedro Coelho, Thomas S. B. Schmidt, Alexandre Almeida, Alex L Mitchell, Robert D. Finn, Jaime Huerta-Cepas, Peer Bork, Georg Zeller, Shinichi Sunagawa in Nature Communications (2019). Community‐Level Responses to Iron Availability in Open Ocean Planktonic Ecosystems by Luigi Caputi, Quentin Carradec, Damien Eveillard, Amos Kirilovsky, Eric Pelletier, Juan J Pierella Karlusich, Fabio Rocha Jimenez Vieira, Emilie Villar, Samuel Chaffron, Shruti Malviya, Eleonora Scalco, Silvia G. Acinas, Adriana Alberti, Jean-Marc Aury, Anne-Sophie Benoiston, Alexis Bertrand, Tristan Biard, Lucie Bittner, Martine Boccara, Jennifer R. Brum, Christophe Brunet, Greta Busseni, Anna Carratalà, Hervé Claustre, Luis Pedro Coelho, Sébastien Colin, Salvatore D'Aniello, Corinne Da Silva, Marianna Del Core, Hugo Doré, Stéphane Gasparini, Florian Kokoszka, Jean-Louis Jamet, Christophe Lejeusne, Cyrille Lepoivre, Magali Lescot, Gipsi Lima-Mendez, Fabien Lombard, Julius Luke?, Nicolas Maillet, Mohammed-Amin Madoui, Elodie Martinez, Maria Grazia Mazzocchi, Mario B. Néou, Javier Paz-Yepes, Julie Poulain, Simon Ramondenc, Jean-Baptiste Romagnan, Simon Roux, Daniela Salvagio Manta, Remo Sanges, Sabrina Speich, Mario Sprovieri, Shinichi Sunagawa, Vincent Taillandier, Atsuko Tanaka, Leila Tirichine, Camille Trottier, Julia Uitz, Alaguraj Veluchamy, Jana Veselá, Flora Vincent, Sheree Yau, Stefanie Kandels-Lewis, Sarah Searson, Céline Dimier, Marc Picheral, Tara Oceans Coordinators, Peer Bork, Emmanuel Boss, Colomban de Vargas, Michael J. Follows, Nigel Grimsley, Lionel Guidi, Pascal Hingamp, Eric Karsenti, Paolo Sordino, Lars Stemmann, Matthew B. Sullivan, Alessandro Tagliabue, Adriana Zingone, Laurence Garczarek, Fabrizio d'Ortenzio, Pierre Testor, Fabrice Not, Maurizio Ribera d'Alcalà, Patrick Wincker, Chris Bowler, Daniele Iudicone in Global Biogeochemical Cycles (2019). Extensive transmission of microbes along the gastrointestinal tract by Thomas Sebastian Benedikt Schmidt, Matthew Robert Hayward, Luis Pedro Coelho, Simone S Li, Paul Igor Costea, Anita Yvonne Voigt, Jakob Wirbel, Oleksandr M Maistrenko, Renato JC Alves, Emma Bergsten, Carine de Beaufort, Iradj Sobhani, Anna Heintz-Buschart, Shinichi Sunagawa, Georg Zeller, Paul Wilmes, Peer Bork in eLife (2019). Recovery of gut microbiota of healthy adults following antibiotic exposure by Albert Palleja, Kristian H Mikkelsen, Sofia K Forslund, Alireza Kashani, Kristine H Allin, Trine Nielsen, Tue H Hansen, Suisha Liang, Qiang Feng, Chenchen Zhang, Paul Theodor Pyl, Luis Pedro Coelho, Huanming Yang, Jian Wang, Athanasios Typas, Morten F. Nielsen, Henrik Bjorn Nielsen, Peer Bork, Jun Wang, Tina Vilsb?ll, Torben Hansen, Filip K. Knop, Manimozhiyan Arumugam, Oluf Pedersen in Nature microbiology (2018). Structure and function of the global topsoil microbiome by Mohammad Bahram, Falk Hildebrand, Sofia K Forslund, Jennifer L Anderson, Nadejda A Soudzilovskaia, Peter M Bodegom, Johan Bengtsson-Palme, Sten Anslan, Luis Pedro Coelho, Helery Harend, Jaime Huerta-Cepas, Marnix H. Medema, Mia R. Maltz, Sunil Mundra, P?l Axel Olsson, Mari Pent, Sergei P?lme, Shinichi Sunagawa, Martin Ryberg, Leho Tedersoo, Peer Bork in Nature (2018). NG-meta-profiler: fast processing of metagenomes using NGLess, a domain-specific language by Luis Pedro Coelho, Renato Alves, Paulo Monteiro, Jaime Huerta-Cepas, Ana Teresa Freitas, Peer Bork in Microbiome (2019). Similarity of the dog and human gut microbiomes in gene content and response to diet by Luis Pedro Coelho, Jens Roat Kultima, Paul Igor Costea, Coralie Fournier, Yuanlong Pan, Gail Czarnecki-Maulden, Matthew Robert Hayward, Sofia K Forslund, Thomas Sebastian Benedikt Schmidt, Patrick Descombes, Janet R. Jackson, Qinghong Li, Peer Bork in Microbiome (2018). Selective maternal seeding and environment shape the human gut microbiome by Katri Korpela, Paul Igor Costea, Luis Pedro Coelho, Stefanie Kandels-Lewis, Gonneke Willemsen, Dorret I Boomsma, Nicola Segata, Peer Bork in Genome Research (2018). Subspecies in the global human gut microbiome by Paul I Costea, Luis Pedro Coelho, Shinichi Sunagawa, Robin Munch, Jaime Huerta‐Cepas, Kristoffer Forslund, Falk Hildebrand, Almagul Kushugulova, Georg Zeller, Peer Bork in Molecular Systems Biology (2017). Quantitative 3D-imaging for cell biology and ecology of environmental microbial eukaryotes by Sebastien Colin, Luis Pedro Coelho, Shinichi Sunagawa, Chris Bowler, Eric Karsenti, Peer Bork, Rainer Pepperkok, Colomban de Vargas in eLife (2017). Jug: Software for Parallel Reproducible Computation in Python by Luis Pedro Coelho in Journal of Open Research Software (2017). Towards standards for human fecal sample processing in metagenomic studies by Paul I Costea, Georg Zeller, Shinichi Sunagawa, Eric Pelletier, Adriana Alberti, Florence Levenez, Melanie Tramontano, Marja Driessen, Rajna Hercog, Ferris-Elias Jung, Jens Roat Kultima, Matthew R Hayward, Luis Pedro Coelho, Emma Allen-Vercoe, Laurie Bertrand, Michael Blaut, Jillian R M Brown, Thomas Carton, Stéphanie Cools-Portier, Michelle Daigneault, Muriel Derrien, Anne Druesne, Willem M de Vos, B Brett Finlay, Harry J Flint, Francisco Guarner, Masahira Hattori, Hans Heilig, Ruth Ann Luna, Johan van Hylckama Vlieg, Jana Junick, Ingeborg Klymiuk, Philippe Langella, Emmanuelle Le Chatelier, Volker Mai, Chaysavanh Manichanh, Jennifer C Martin, Clémentine Mery, Hidetoshi Morita, Paul W O'Toole, Céline Orvain, Kiran Raosaheb Patil, John Penders, S?ren Persson, Nicolas Pons, Milena Popova, Anne Salonen, Delphine Saulnier, Karen P Scott, Bhagirath Singh, Kathleen Slezak, Patrick Veiga, James Versalovic, Liping Zhao, Erwin G Zoetendal, S Dusko Ehrlich, Joel Dore, Peer Bork in Nature biotechnology (2017). metaSNV: A tool for metagenomic strain level analysis by Paul Igor Costea, Robin Munch, Luis Pedro Coelho, Lucas Paoli, Shinichi Sunagawa, Peer Bork in PloS one (2017). Fast genome-wide functional annotation through orthology assignment by eggNOG-mapper by Jaime Huerta-Cepas, Kristoffer Forslund, Luis Pedro Coelho, Damian Szklarczyk, Lars Juhl Jensen, Christian von Mering, Peer Bork in Mol Biol Evol (2017). Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-na?ve Parkinson’s disease patients by Janis R Bedarf, Falk Hildebrand, Luis P Coelho, Shinichi Sunagawa, Mohammad Bahram, Felix Goeser, Peer Bork, Ullrich Wüllner in Genome medicine (2017). MOCAT2: a metagenomic assembly, annotation and profiling framework by Jens Roat Kultima, Luis Pedro Coelho, Kristoffer Forslund, Jaime Huerta-Cepas, Simone S Li, Marja Driessen, Anita Yvonne Voigt, Georg Zeller, Shinichi Sunagawa, Peer Bork in Bioinformatics (2016). Plankton networks driving carbon export in the oligotrophic ocean by Lionel Guidi, Samuel Chaffron, Lucie Bittner, Damien Eveillard, Abdelhalim Larhlimi, Simon Roux, Youssef Darzi, Stephane Audic, Léo Berline, Jennifer Brum in Nature (2016). Gene expression changes in the salivary glands of Anopheles coluzzii elicited by Plasmodium berghei infection by Renato Pinheiro-Silva, Lara Borges, Luis Pedro Coelho, Alejandro Cabezas-Cruz, James J Valdés, Virgilio Do Rosario, José De La Fuente, Ana Domingos in Parasites & vectors (2015). Structure and function of the global ocean microbiome by Shinichi Sunagawa, Luis Pedro Coelho, Samuel Chaffron, Jens Roat Kultima, Karine Labadie, Guillem Salazar, Bardya Djahanschiri, Georg Zeller, Daniel R Mende, Adriana Alberti, Francisco M Cornejo-Castillo, Paul I Costea, Corinne Cruaud, Francesco d'Ovidio, Stefan Engelen, Isabel Ferrera, Josep M Gasol, Lionel Guidi, Falk Hildebrand, Florian Kokoszka, Cyrille Lepoivre, Gipsi Lima-Mendez, Julie Poulain, Bonnie T Poulos, Marta Royo-Llonch, Hugo Sarmento, Sara Vieira-Silva, Céline Dimier, Marc Picheral, Sarah Searson, Stefanie Kandels-Lewis, Tara Oceans coordinators; Chris Bowler, Colomban de Vargas, Gabriel Gorsky, Nigel Grimsley, Pascal Hingamp, Daniele Iudicone, Olivier Jaillon, Fabrice Not, Hiroyuki Ogata, Stephane Pesant, Sabrina Speich, Lars Stemmann, Matthew B Sullivan, Jean Weissenbach, Patrick Wincker, Eric Karsenti, Jeroen Raes, Silvia G Acinas, Peer Bork in Science (2015). Automatic determination of NET (neutrophil extracellular traps) coverage in fluorescent microscopy images by Luis Pedro Coelho, Catarina Pato, Ana Fri?es, Ariane Neumann, Maren von K?ckritz-Blickwede, Mário Ramirez, Joao Andre Carrico in Bioinformatics (2015). Trypanosoma brucei histone H1 inhibits RNA polymerase I transcription and is important for parasite fitness in vivo by Ana C Pena, Mafalda R Pimentel, Helena Manso, Rita Vaz‐Drago, Daniel Pinto‐Neves, Francisco Aresta‐Branco, Filipa Rijo‐Ferreira, Fabien Guegan, Luis Pedro Coelho, Maria Carmo‐Fonseca, Nuno L. Barbosa-Morais, Luisa M. Figueiredo in Molecular microbiology (2014). Metagenomic insights into the human gut resistome and the forces that shape it by Kristoffer Forslund, Shinichi Sunagawa, Luis P Coelho, Peer Bork in BioEssays (2014). Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection by Peter Liehl, Vanessa Zuzarte-Luís, Jennie Chan, Thomas Zillinger, Fernanda Baptista, Daniel Carapau, Madlen Konert, Kirsten K Hanson, Céline Carret, Caroline Lassnig, Mathias Müller, Ulrich Kalinke, Mohsan Saeed, Angelo Ferreira Chora, Douglas T Golenbock, Birgit Strobl, Miguel Prudêncio, Luis P Coelho, Stefan H Kappe, Giulio Superti-Furga, Andreas Pichlmair, Ana M Vigário, Charles M Rice, Katherine A Fitzgerald, Winfried Barchet, Maria M Mota in Nature medicine (2014). Metagenomic species profiling using universal phylogenetic marker genes by Shinichi Sunagawa, Daniel R Mende, Georg Zeller, Fernando Izquierdo-Carrasco, Simon A Berger, Jens Roat Kultima, Luis Pedro Coelho, Manimozhiyan Arumugam, Julien Tap, Henrik Bj?rn Nielsen, Simon Rasmussen, S?ren Brunak, Oluf Pedersen, Francisco Guarner, Willem M de Vos, Jun Wang, Junhua Li, Jo?l Doré, S Dusko Ehrlich, Alexandros Stamatakis, Peer Bork in Nature methods (2013). Determining the subcellular location of new proteins from microscope images using local features by Luis Pedro Coelho, Joshua D Kangas, Armaghan W Naik, Elvira Osuna-Highley, Estelle Glory-Afshar, Margaret Fuhrman, Ramanuja Simha, Peter B Berget, Jonathan W Jarvik, Robert F Murphy in Bioinformatics (2013). Mahotas: Open source software for scriptable computer vision by Luis Pedro Coelho in Journal of Open Research Software (2013). Dotted suffix trees: a structure for approximate text indexing by Luis Coelho, Arlindo Oliveira in String Processing and Information Retrieval (2006). Identifying Subcellular Locations from Images of Unknown Resolution by Luis Pedro Coelho, Robert F Murphy in International Conference on Bioinformatics Research and Development (2008). Structured literature image finder: extracting information from text and images in biomedical literature by Luis Pedro Coelho, Amr Ahmed, Andrew Arnold, Joshua Kangas, Abdul-Saboor Sheikh, Eric P Xing, William W Cohen, Robert F Murphy in Linking Literature, Information, and Knowledge for Biology (2010). Structured literature image finder: Parsing text and figures in biomedical literature by Amr Ahmed, Andrew Arnold, Luis Pedro Coelho, Joshua Kangas, Abdul-Saboor Sheikh, Eric Xing, William Cohen, Robert F Murphy in Web Semantics: Science, Services and Agents on the World Wide Web (2010). Cell cycle dependence of protein subcellular location inferred from static, asynchronous images by Taráz E Buck, Arvind Rao, Luis Pedro Coelho, Margaret H Fuhrman, Jonathan W Jarvik, Peter B Berget, Robert F Murphy in 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (2009). Automated image analysis for high-content screening and analysis by Aabid Shariff, Joshua Kangas, Luis Pedro Coelho, Shannon Quinn, Robert F Murphy in Journal of biomolecular screening (2010). Principles of bioimage informatics: focus on machine learning of cell patterns by Luis Pedro Coelho, Estelle Glory-Afshar, Joshua Kangas, Shannon Quinn, Aabid Shariff, Robert F Murphy in Linking Literature, Information, and Knowledge for Biology (2010). Quantifying the distribution of probes between subcellular locations using unsupervised pattern unmixing by Luis Pedro Coelho, Tao Peng, Robert F Murphy in Bioinformatics (2010). An adaptive multiresolution approach to fingerprint recognition by Amina Chebira, Luis P Coelho, Aliaksei Sandryhaila, Stephen Lin, William G Jenkinson, Jeremiah MacSleyne, Christopher Hoffman, Philipp Cuadra, Charles Jackson, Markus Püschel in Image Processing, 2007. ICIP 2007. IEEE International Conference on (2007). Nuclear segmentation in microscope cell images: a hand-segmented dataset and comparison of algorithms by Luis Pedro Coelho, Aabid Shariff, Robert F Murphy in Biomedical Imaging: From Nano to Macro, 2009. ISBI09. IEEE International Symposium on (2009).

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