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个人简介

罗强,博士,研究员,博士生导师,致力于发展多维度脑科学复杂数据整合分析新方法,及其在青少年脑发育和精神健康方面的应用研究,主持了国家自然科学基金3项、获国家发明专利1项、发表学术论文50余篇,包括精神疾病领域顶级期刊JAMA Psychiatry、Biological Psychiatry、American Journal of Psychiatry和脑影像数据分析与建模权威期刊 NeuroImage、PloS Computational Biology等,受邀为JAMA Psychiatry撰写特约评论;研究成果得到新华网、科学网、Science Daily、Daily Mail等国内外主流媒体报道。受邀担任英国伦敦国王学院高级访问讲师、上海市非线性科学研究会理事会副秘书长、Frontiers in Psychiatry期刊编辑,医学1区SCI期刊Psychological Medicine编委,并于2018年入选剑桥大学克莱尔学堂客座研究员。目前招收硕士、博士(统计学、心理学、生物医学、计算机科学)、并与复旦大学特聘教授、英国剑桥大学Trevor Robbins教授、Barbara Sahakian教授合作招收博士和博士后(认知神经科学、生物医学大数据挖掘、人工智能)。 工作经历 2022.9- 至今 复旦大学 研究员 2019.12-至今 复旦大学 长聘副研究员、博导 2018.12-2019.12 英国剑桥大学(Clare Hall) 客座研究员 2016.10-2019.9 英国伦敦国王学院 访问高级讲师 2015.9-2015.12 英国伦敦国王学院 访问学者 2015.1-2019.11 复旦大学 青年副研究员 2013.1-2014.12 上海数学中心 博士后、合作导师:冯建峰教授 2010.6 –2013.12 国防科大 讲师 教育背景 2008.9-2009.9 英国牛津大学统计系联合培养博士生 C.Deane教授,G.Reinert教授 2006.3-2010.6 国防科大理学院数学与系统科学系博士研究生 易东云教授 2004.9-2006.1 国防科大理学院数学系硕士研究生 刘普寅教授 2000.9-2004.6 国防科大理学院 应用数学系本科生

研究领域

计算神经科学、智能医学

近期论文

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Jonathan W. Kanen+, Qiang Luo+, et al., Hanneke E.M. den Ouden. Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans, Psychological Medicine 2022 (共一;医学1区;IF= 10.592) Ruihan Yang, et al., Colin Camerer, Read Montague, Qiang Luo. Dynamic neural reconfiguration for distinct strategies during competitive social interactions, NeuroImage 2022, 119585, https://doi.org/10.1016/j.neuroimage.2022.119585. (通讯作者;医学1区;IF= 7.2) Qingyang Li, Lingli Zhang, et al., Qiang Luo* and Fei Li*. The immuno-behavioural covariation associated with the treatment response to bumetanide in young children with autism spectrum disorder. Translational Psychiatry 12, 228 (2022). https://doi.org/10.1038/s41398-022-01987-x (共同通讯;医学2区;IF= 7.98) Han Lu, et al., Qiang Luo*, Yu Zhou*, Jianmin Liu. Prognostic Prediction Associated with Surgical Difficulty in Patients after Aneurysmal Subarachnoid Hemorrhage with Endovascular Treatment. Therapeutic Advances in Neurological Disorders 15, 2022. https://doi.org/10.1177/17562864221099473 (共同通讯;医学2区;IF= 6.43) Luo Q, Sahakian BJ. Brain sex differences: the androgynous brain is advantageous for mental health and well-being. Neuropsychopharmacology, 47, 407–408, 2022. doi: 10.1038/s41386-021-01141-z. (第一作者;医学1区;IF= 8.29) Yan Sun, et al., Qiang Luo, et al., Gunter Schumann, IMAGEN Consortia. Associations of DNA methylation with behavioral problems, grey matter volumes and negative life events across adolescence: Evidence from the longitudinal IMAGEN study. Biological Psychiatry. 2022. https://doi.org/10.1016/j.biopsych.2022.06.012 Yuan Dai, et al., Qiang Luo, et al., Fei Li. Shanghai Autism Early Development: An Integrative Chinese ASD Cohort. Neurosci. Bull. (2022). https://doi.org/10.1007/s12264-022-00904-y. 罗强+, 罗雅楠+, 冯娜娜, 李清扬, 郑晓瑛. 阿尔茨海默病早期诊断技术前沿概述. 中国公共卫生, 2022 (修回;协和医学院合作) Xu, J., Liu, X., Li, Q.,Goldblatt, R., Qin, W., Liu, F., Chu, C., Luo,Q., et al. Global urbanicity is associated with brain and behaviour in young people. Nat Hum Behav (2021). https://doi.org/10.1038/s41562-021-01204-7 Yi Zhang, Qiang Luo*, et al. The Human Brain is Best Described as Being on a Female/Male Continuum: Evidence from a Neuroimaging Connectivity Study. Cerebral Cortex, 2021, Volume 31, Issue 6, June 2021, Pages 3021–3033. doi:10.1093/cercor/bhaa408. (通讯作者;医学1区;Most Read Article in Cerebral Cortex in Feb 2021; 封面论文) Yuan Dai+, Lingli Zhang+, Juehua Yu+, et al. Qiang Luo*, Fei Li*. Improved symptoms following bumetanide treatment in children aged 3 to 6 years with autism spectrum disorder: a randomized, double-blind, placebo-controlled trial. Science Bulletin, 2021, https://doi.org/10.1016/j.scib.2021.01.008. (共同通讯;综合1区) 同期配发加拿大皇家学会和健康科学院两院院士 Anthony G.Phillips特约评论, Placing old wine into new bottles: Successful repurposing of bumetanide for treatment of autism spectrum disorder, Science Bulletin, 2021 (in press) (https://doi.org/10.1016/j.scib.2021.03.001) Shi, K., Zhang, L., Yu, J., Chen, Z., Lai, S., Zhao, X., Li, W.‐G., Luo, Q., Lin, W., Feng, J., Bork, P., Zhao, X.‐M. and Li, F. (2021), A 12‐genus bacterial signature identifies a group of severe autistic children with differential sensory behavior and brain structures. Clin. Transl. Med., 11: e314. https://doi.org/10.1002/ctm2.314 Kendrick KM, Daumann J, Wagner D, Koester P, Tittgemeyer M, Luo Q, Gouzoulis-Mayfrank E, Becker B. A prospective longitudinal study shows putamen volume is associated with moderate amphetamine use and resultant cognitive impairments. Psychoradiology. Volume 1, Issue 1, March 2021, Pages 3–12. https://doi.org/10.1093/psyrad/kkab001 Lena Palaniyappan, Priyadharshini Sabesan, Xuan Li, Qiang Luo, Schizophrenia increases variability of the central antioxidant system: A meta-analysis of variance from MRS studies of glutathione. Frontiers in Psychiatry 2021, 12. Guowei Wu, Lena Palaniyappan, Manqi Zhang, Jie Yang, Chang Xi, Zhening Liu, Zhimin Xue, Xuan Ouyang, Haojuan Tao, Jinqiang Zhang, Qiang Luo, Weidan Pu, Imbalance Between Prefronto-Thalamic and Sensorimotor-Thalamic Circuitries Associated with Working Memory Deficit in Schizophrenia, Schizophrenia Bulletin, 2021, sbab086, https://doi.org/10.1093/schbul/sbab086 Luo, Q., Zhang, L., Huang, C. et al. Association between childhood trauma and risk for obesity: a putative neurocognitive developmental pathway. BMC Med 18, 278 (2020). https://doi.org/10.1186/s12916-020-01743-2 Qiang Luo, Baobao Pan, Huaguang Gu, Molly Simmonite, Susan Francis, Peter F. Liddle, Lena Palaniyappan, Effective connectivity of the right anterior insula in schizophrenia: the salience network and task-negative to task-positive transition, NeuroImage: Clinical, 2020,102377, https://doi.org/10.1016/j.nicl.2020.102377. Chun Shen, Qiang Luo*, Samuel R. Chamberlain, et al., Barbara J Sahakian, What is the Link between Attention-Deficit/Hyperactivity Disorder and Sleep? A multimodal examination of longitudinal relationships and brain structure using large-scale cohorts. Biological Psychiatry, 31 March, 2020. https://doi.org/10.1016/j.biopsych.2020.03.010 (In this study, we have used block-based permutation to account for the family relatedness in the ABCD cohort. The code is available at the following link: https://github.com/qluo2018/FamilyPermutationABCD. ) Chun Shen, Qiang Luo*, et al., Barbara J Sahakian. Neural correlates of the dual pathway model for attention-deficit/hyperactivity disorder in adolescents. The American Journal of Psychiatry. (https://doi.org/10.1176/appi.ajp.2020.19020183) (The code of this study is available at the following link: https://github.com/qluo2018/DualPathwayADHD. ) Lingli Zhang, et al. Qiang Luo*, et al., Barbara J Sahakian, Ching-Po Lin*, Fei Li*. Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios. Translational Psychiatry 10, Article number: 9 (2020) https://www.nature.com/articles/s41398-020-0692-2. Press Releases: Eurekalert; News-medical; Times; Sun; Daily Mail; Metro; ScienceAlert; TechExplorist; UPI; BBC Radio Interview; The Conversation; Chu-Chung Huang+, Qiang Luo+, Lena Palaniyappan+, et al. Deanna M. Barch, Jianfeng Feng, Ching-Po Lin, Trevor W. Robbins. Transdiagnostic and Illness-specific Functional Dysconnectivity Across Schizophrenia, Bipolar Disorder and Major Depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. Volume 5, Issue 5, May 2020, Pages 542-553 (https://doi.org/10.1016/j.bpsc.2020.01.010) 被选为封面文章 [Cover Article] 代码:https://github.com/wayalan/TransdiagnosticFC Banca, P., McNamee, D., Piercy, T., Luo, Q., & Robbins, T. W. (2020). A Mobile Phone App for the Generation and Characterization of Motor Habits. Frontiers in psychology, 10, 2850. doi:10.3389/fpsyg.2019.02850. Tianye Jia, et al. Qiang Luo, et al., Gunter Schumann. Neurobehavioural characterisation and stratification of reinforcement-related behaviour. Nature Human Behaviour. 2020. (https://doi.org/10.1038/s41562-020-0846-5) Chao Xie, et al., Qiang Luo, et al., Reward Versus Nonreward Sensitivity of the Medial Versus Lateral Orbitofrontal Cortex Relates to the Severity of Depressive Symptoms,Biological Psychiatry: Cognitive Neuroscience and Neuroimaging (BP:CNNI), 2020, ISSN 2451-9022, https://doi.org/10.1016/j.bpsc.2020.08.017. Hsinsung Yuan, et al., Qiang Luo*. Connectivity between the Anterior Insula and Dorsolateral Prefrontal Cortex Links Early Symptom Improvement to Treatment Response. Journal of Affective Disorders, 1 January, 260, 490-497 (2020). (https://doi.org/10.1016/j.jad.2019.09.041) Hongtao Ruan, Qiang Luo*, et al., Topographic diversity of structural connectivity in schizophrenia. Schizophrenia Research. 2020 January, 215, 181-189. (https://doi.org/10.1016/j.schres.2019.10.034) Qiang Luo, Qiang Chen, Wenjia Wang, et al., Jianfeng Feng, for the IMAGEN consortium. Association of a Schizophrenia-Risk Nonsynonymous Variant With Putamen Volume in Adolescents: A Voxelwise and Genome-Wide Association Study. JAMA Psychiatry. 2019 Apr 1; 76(4):435-445. doi: 10.1001/jamapsychiatry.2018.4126. 媒体报道: China Daily; Medscape; Science Daily; Warwick University; Deutsches ?rzteblatt; 新华社; 光明日报;科学网;… 点评:西班牙圣地亚哥健康研究院精神疾病遗传学研究组负责人Javier Costas资深研究员在接收Medscape采访时,评价我们的一项研究成果为important finding和astonishing result. Gabriel Robert#, Qiang Luo#, et al., Gunter Schumann, for the IMAGEN consortium. Grey matter and personality development during adolescence and the increase of drunkenness frequency: a longitudinal population-based approach. JAMA Psychiatry JAMA Psychiatry. 2020;77(4):409-419. https://doi.org/10.1001/jamapsychiatry.2019.4063. 媒体报道: KCL News Centre; Daily Mail; Inverse; Medscape; MedicalXpress; Infosurhoy; … 点评:德国埃朗根-纽伦堡大学Christian P Müller教授认为,我们研究了一个非常有趣的“very interesting”、适时的“timely”、悬而未决的问题“had not been resolved so far”,该重要发现对于我们理解酒精成瘾风险的发育形成机制将产生深远的影响“an important finding that may have wide ranging implication on the view of how alcohol addiction risks build up during development”。 Qiang Luo*, et al., Trevor Robbins. Association between Childhood Trauma and Risk for Obesity: A putative neurocognitive development pathway. (under preparation) Evangelos Evangelou, He Gao, et al., Qiang Luo, et al., Gunter Schumann, Paul Elliott. New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders. Nature Human Behaviour. 29 July, 3, 950–961 (2019). https://doi.org/10.1038/s41562-019-0653-z Tay N, Macare C, Liu Y, Ruggeri B, Jia T, Chu C, Biondo F, Ing A, Luo Q, et al., Gunter Schumann, and for the IMAGEN Consortium. Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse. American Journal of Psychiatry, 2019 Feb 1;176(2):146-155. doi: 10.1176/appi.ajp.2018.17121360. Tao Yu, et al., Qiang Luo, et al., Lin He, Gunter Schumann, Gabriel Robert, and for the IMAGEN Consortium, Cannabis-Associated Psychotic-Like Experiences Are Mediated by Developmental Changes in the Parahippocampal Gyrus, Journal of the American Academy of Child & Adolescent Psychiatry, 2019, ISSN 0890-8567, https://doi.org/10.1016/j.jaac.2019.05.034 Ruan, H., Y. Zhou, Q. Luo*, et al. (2019). “Adolescent binge drinking disrupts normal trajectories of brain functional organization and personality maturation.” NeuroImage: Clinical 22: 101804. https://doi.org/10.1016/j.nicl.2019.101804. Wang K; et al., Luo Q*; Li F*, Altered social cognition and connectivity of default mode networks in the co-occurrence of autistic spectrum disorder and attention deficit hyperactivity disorder, Australian & New Zealand Journal of Psychiatry. 2019 Aug;53(8):760-771. [Epub ahead of print] https://doi.org/10.1177/0004867419836031 Hsinsung Yuan, Xiao Zhu, Qiang Luo, et al., Shenxun Shi. Early symptom non-improvement and aggravation are associated with the treatment response to SSRIs in MDD: a real-world study. Neuropsychiatric Disease and Treatment 2019;15:957—966. https://doi.org/10.2147/NDT.S196533 Yuan Xinsong, Zhu Xiao, Shen Chun, Luo Qiang, Shi Shenxun. Trajectory analysis of single-drug therapy for first-episode major depression disorder. 中华行为医学与脑科学杂志 (Chin J Behav Med & Brain Sci), June 2019,Vol. 28,No. 6. (in Chinese) Yanhao Ren, Qiang Luo, Weikang Gong, and Wenlian Lu. 2019. Transfer Learning Models on Brain Age Prediction. In Proceedings of the Third International Symposium on Image Computing and Digital Medicine (ISICDM 2019). Association for Computing Machinery, New York, NY, USA, 278–282. DOI:https://doi.org/10.1145/3364836.3364893 Erin Burke Quinlan, Edward D. Barker, Qiang Luo, et al., Gunter Schumann & IMAGEN Consortium. Peer victimization and its impact on adolescent brain development and psychopathology. Molecular Psychiatry, 2020, 25: 3066–3076. doi: 10.1038/s41380-018-0297-9. [2018 Dec 12; Epub ahead of print] Le-Heng Fang, Wei Lin*, and Qiang Luo. Brain-Inspired Constructive Learning Algorithms with Evolutionally Additive Nonlinear Neurons. Int. J. Bifurcation Chaos,2018,28, 1850068. Luo Qiang#, Ma Yina#, Bhatt Meghana A.#,, Montague P. Read*, Feng Jianfeng*, The Functional Architecture of the Brain Underlies Strategic Deception in Impression Management, Frontiers in Human Neuroscience, 2017, 11, 513. Yanbing Jia, Huaguang Gu*, Qiang Luo*, Sample entropy reveals an age-related reduction in the complexity of dynamic brain, Scientific Reports, 2017,7, 7990. Code Wei Cheng, Edmund T. Rolls, Jie Zhang, Wenbo Sheng, Liang Ma, Lin Wan, Qiang Luo, Jianfeng Feng, Functional connectivity decreases in autism in emotion, self, and face circuits identified by Knowledge-based Enrichment Analysis, NeuroImage, 2017, 148:169-178. Pu W, Luo Q, Jiang Y, Gao Y, Ming Q, Yao S(*). Alterations of Brain Functional Architecture Associated with Psychopathic Traits in Male Adolescents with Conduct Disorder. Scientific Reports. 2017;7:11349. doi:10.1038/s41598-017-11775-z. Pu, W#,Luo, Q#,Palaniyappan, L#,Xue, Z,Yao, S,Feng, J*,Liu, Z*,Failed cooperative, but not competitive, interaction between large-scale brain networks impairs working memory in schizophrenia., Psychological Medicine,2016,46(6):1211-24. Li T et al., Qiang Luo, et al., Brain-Wide Analysis of Functional Connectivity in First-Episode and Chronic Stages of Schizophrenia. Schizophrenia Bulletin. 2016 Jul 21. pii: sbw099. Cohen Kadosh K*,Qiang Luo,Calem de Burca,Moses O. Sokunbi,Jianfeng Feng,David E.J. Lindene,Jennifer Y.F. Lau,Using real-time fMRI to influence effective connectivity in the developing emotion regulation network,NeuroImage,2015,(125):616-626. Wei Cheng,et al.,Qiang Luo,et al.,Voxel-based, brain-wide association study of aberrant functional connectivity in schizophrenia implicates thalamocortical circuitry,npj Schizophrenia,2015,(1). Qiang Luo,Tian Ge,Fabian Grabenhorst,Edmund Rolls*,Jianfeng Feng*,Attention-dependent modulation of cortical taste circuits revealed by granger causality with signal-dependent noise,PLoS Computational Biology,2013,9(10). 点评:复杂系统信息流研究国际权威英国Sussex大学Lionel Barnett研究员(在PRL和PNAS上发表了多篇因果网络推断方法的论文)在期刊《Physical Review Letters》上的正面评价:认为传统方法通过不断升高经典时间序列模型的阶数来拟合复杂数据,造成了数据的统计结构很难解释和模型过拟合,而候选人发展的异方差模型是一种很好的解决方案。 Luo, Qiang#,Lu, Wenlian#,Cheng, Wei#,Valdes-Sosa, Pedro A.,Wen, Xiaotong,Ding, Mingzhou,Feng, Jianfeng*,Spatio-temporal Granger causality: A new framework,NeuroImage,2013,79:241-263. Luo, Qiang*,Hamer, Rebecca,Reinert, Gesine,Deane, Charlotte M.,Local Network Patterns in Protein-Protein Interfaces,PLos One,2013,8(3). Xu Liu,Jeffrey Yi-Lin Forrest,Qiang Luo,Dong-Yun Yi*,Detecting community structure using biased random merging,Physica A: Statistical Mechanics and Its Applications,2012,391(4):1797-1810.

学术兼职

中国电子信息学会智能人机交互专委会专家 上海非线性科学研究会副秘书长 《Psychological Medicine》杂志(医学1区;IF>10)编委 《Frontiers in Neuroimage》系列杂志Associate Editor 《Frontiers in Psychiatry》专辑《Digital Phenotyping/Digital Biomarkers to Monitor Psychiatric Disorders》的Topic Editor 为《Biological Psychiatry》、《Lancet Psychiatry》、《Psychological Medicine》等权威期刊审稿 曾任国际会议International Joint Conference on Artificial Intelligence (IJCAI-16)的程序委员会委员,第六届上海非线性科学国际研讨会(Shanghai NSA 2016)的组织委员会共同主席,国际会议Complex’2009担任技术程序委员会委员

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