个人简介
赵兴明，复旦大学类脑智能科学与技术研究院教授，计算神经科学与类脑智能教育部重点实验室副主任、张江国际脑库执行主任、上海市青年科技启明星和上海市浦江人才计划入选者，IEEE Senior Member、IEEE SMC TC on Systems Biology Co-Chair、IEEE SMC Shanghai Chapter Chair、ACM SIGBio China Vice Chair、CCF 高级会员、中国人工智能学会人工生命与生物信息学专委会副主任、中国计算机学会生物信息学专委会常务委员、上海市计算机学会生物信息学专委会主任等。承担了863、国家重点研发计划、国家自然科学基金重大研究计划和重点项目在内的多项科研课题。在Nature、Cell Metabolism、IEEE TPAMI、Nature Communications、Genome Medicine、Nucleic Acids Research等国际著名期刊发表SCI论文100余篇， 以第一完成人荣获吴文俊人工智能自然科学一等奖（2020年）和教育部高等学校科学研究优秀成果（自然类）二等奖（2018年）。
近期论文
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TadA reprogramming to generate potent miniature base editors with high precision S Zhang L Song B Yuan C Zhang J Cao J Chen J Qiu Y Tai J Chen Z Qiu XM Zhao TL Cheng Nature Communications2023
Co-VAE: Drug-target binding affinity prediction by co-regularized variational autoencoders T Li XM Zhao L Li IEEE Pattern Analysis and Machine Intelligence2022
metaMIC: reference-free Misassembly Identification and Correction of de novo metagenomic assemblies S Lai S Pan C Sun L.P Coelho WH Chen XM Zhao Genome Biology2022
A deep siamese neural network improves metagenome-assembled genomes in microbiome datasets across different environments S Pan C Zhu XM Zhao Coelho LP Nature Communications2022
Disrupted long-range gene regulations elucidate shared tissue-specific mechanisms of neuropsychiatric disorders J Chen L Song A Yang G Dong XM Zhao Molecular psychiatry2022
Towards the biogeography of prokaryotic genes L.P Coelho R Alves Río, á. R Del P. N Myers C. P Cantalapiedra J Giner-Lamia T. S Schmidt D. R Mende A Orakov I Letunic F Hildebrand T Van Rossum S. K Forslund S Khedkar O.M Maistrenko S Pan L Jia P Ferretti S Sunagawa XM Zhao H.B Nielsen J Huerta-Cepas P Bork Nature2021
Identifying age-specific gene signatures of the human cerebral cortex with joint analysis of transcriptomes and functional connectomes X Zhao J Chen P Xiao J Feng Q Nie XM Zhao Briefings in Bioinformatics2021
A Global Overview of Genetically Interpretable Multimobidities among Common Diseases in the UK Biobank G Dong J Feng F Sun J Chen XM Zhao Genome Medicine2021
Treatment regimens may compromise gut-microbiome-derived signatures for liver cirrhosis S Wu P Jiang XM Zhao WH Chen Cell metabolism2021
A 12-genus bacterial signature identifies a group of severe autistic children with differential sensory behavior and brain structures K Shi L Zhang J Yu Z Chen S Lai X Zhao WG Li Q Luo W Lin J Feng J P Bork XM Zhao F Li Clinical and translational medicine2021
STAB: a spatio-temporal cell atlas of the human brain L Song S Pan Z Zhang L Jia WH Chen XM Zhao Nucleic Acids Research2021
HISP: a hybrid intelligent approach for identifying directed signaling pathways XM Zhao S Li Journal of Molecular Cell Biology2017
Integrative analysis of mutational and transcriptional profiles reveals driver mutations of metastatic breast cancers JH Lee XM Zhao I Yoon JY Lee NH Kwon YY Wang KM Lee MJ Lee J Kim HG Moon Y In JK Hao KM Park DY Noh W Han S Kim Cell Discovery2016
PPIM: A protein-protein interaction database for maize G Zhu A Wu XJ Xu PP Xiao L Lu J Liu Y Cao L Chen J Wu XM Zhao Plant Physiology2016
The drug cocktail network KJ Xu J Song XM Zhao BMC Systems Biology2012
Prediction of drug combinations by integrating molecular and pharmacological data XM Zhao M Iskar G Zeller M Kuhn V van Noort P Bork PLoS Computational Biology2011
A systems biology approach to identify effective cocktail drugs Z Wu XM Zhao L Chen BMC Systems Biology2010
A discriminative approach for identifying domain-domain interactions from protein-protein interactions XM Zhao L Chen K Aihara Proteins2010
Uncovering signal transduction networks from high-throughput data by integer linear programming XM Zhao RS Wang L Chen K Aihara Nucleic Acids Research2008
Gene function prediction using labeled and unlabeled data XM Zhao Y Wang LN Chen K Aihara BMC Bioinformatics2008
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